|
The document is a laboratory report from 3M Environmental Laboratory detailing the analysis of PFOA, PFOS, PFHSI, and PFBS in groundwater and surface water samples collected near the 3M Decatur facility, conducted under modified method ETS-8-154.1.
|
1999 |
AR226-3686
|
wm2KpXoEO05GkNxV7VbNdL9o |
21 |
|
The document is a final report from 3M Environmental Laboratory detailing the analysis of perfluorinated compounds, including PFOA and PFOS, in aqueous samples from municipal wells in Oakdale, Minnesota, with revisions made to improve data accuracy for these substances using a validated method.
|
1999 |
AR226-3691
|
Gz4J7xGZe93radK7E9wBnm97 |
21 |
|
The document is a final report from the 3M Environmental Laboratory detailing the analysis of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in aqueous samples collected from 3M Cordova wells and drinking water distribution, conducted under laboratory project number E06-0302.
|
1999 |
AR226-3716
|
mBY2nmmdyXLaMxmb731zmMwXd |
14 |
|
The document is a laboratory report from 3M Environmental Laboratory detailing the analysis of PFOA, PFOS, PFHS, and PFBS in groundwater and surface water samples collected near the 3M Decatur facility, conducted under project number E06-0199 using a modified testing method.
|
1999 |
AR226-3726
|
N2qzDo9LoQrKdkqQZRxw9gByV |
21 |
|
The document is a confidential report from DuPont Specialty Chemicals regarding an acute oral toxicity study of a perfluorinated compound conducted at Huntingdon Life Sciences, with a request for review and comments on the final draft.
|
1999 |
AR226-3109
|
MJ0En5bpZZwZMdMpdk3JarYex |
17 |
|
This document is a final drift report for a mouse micronucleus test conducted by Huntingdon Life Sciences for DuPont Specialty Chemicals, focusing on compliance with Good Laboratory Practice standards and awaiting quality assurance audit before issuing the final report.
|
1999 |
AR226-3110
|
kDqpzqr7j1Xk34QdGmXYZ4M0b |
25 |
|
The document reports on a skin irritation test conducted by DuPont on substances identified as H-23773 and H-23775, which were stable under study conditions, with the study completed on February 19, 1999.
|
1999 |
AR226-3114
|
k9rxEz4rVqE6dre6VQRbVBR5D |
12 |
|
This document is a study report from DuPont detailing the Local Lymph Node Assay (LLNA) for evaluating the potential skin sensitization of a trade secret substance, with the study completed on April 7, 1999.
|
1999 |
AR226-3119
|
pgBYok5ezD171KxZyXpLkLdD |
11 |
|
The document outlines the Canadian Environmental Protection Act (CEPA) 1999's framework for assessing and managing perfluorinated compounds (PFCs), emphasizing the need for risk assessments by Environment Canada and Health Canada to determine the toxicity of new substances, including PFOA and PFOS, before their introduction into Canada.
|
1999 |
AR226-3600
|
e7mdLz3nk0o45983Z7Vpk9xVE |
11 |
|
The document is a study report by DuPont on a skin irritation test conducted on rabbits using a trade secret substance, with the study completed on July 30, 1999.
|
1999 |
AR226-3128
|
3Jp10dd8pkQdYdKG7bRxY9gBJ |
12 |
|
The document reports on an eye irritation test conducted by DuPont on a test substance, evaluating its acute eye irritation potential in rabbits, with no evidence of instability observed during the study.
|
1999 |
AR226-3130
|
aDVQYJo12ZbKL966ZJzLX55Mb |
12 |
|
This document is a certification report for a Local Lymph Node Assay (LLNA) study conducted by DuPont, evaluating the immunotoxicological effects of a substance, with the study completed on August 10, 1999, by Dr. Gregory S. Ladies.
|
1999 |
AR226-3129
|
6wjZgjLjxxJVppo88Lwqg9QY1 |
13 |
|
The document is a confidential report from DuPont Specialty Chemicals detailing a skin sensitization study on a test substance using the Magnusson & Kligman method, conducted by Huntingdon Life Sciences, with results and compliance with good laboratory practice standards included.
|
1999 |
AR226-3127
|
RjmdYg8yeK4VKqwZ5vee1pNwv |
25 |
|
The document reports on a study (H-24119) conducted by E. I. du Pont de Nemours and Company to determine the oral approximate lethal dose (ALD) of a test substance in male rats, indicating that the substance was stable under study conditions.
|
1999 |
AR226-3131
|
4v0zkE1j84722OdDwBJvxq2qN |
8 |
|
This is a study report (H-24256) from E. I. du Pont de Nemours and Company detailing a Local Lymph Node Assay (LLNA) conducted by Gregory S. Ladies, Ph.D., completed on November 15, 1999.
|
1999 |
AR226-3135
|
byL5XLNQY387MVNBYadQbyxV1 |
13 |
|
The document reports on a skin irritation test conducted by DuPont on rabbits using a trade secret substance, evaluating its potential irritative effects.
|
1999 |
AR226-3136
|
NX5KQM7qe9RQ782Rwvmb0xZb |
12 |
|
This document is a confidential skin sensitization study report conducted by Elf Atochem S.A. on a test substance, detailing the methodology and results of the study performed on guinea pigs to assess allergenicity.
|
1999 |
AR226-3134
|
OJ3k8dM8VOv7G5paM13KYNQyX |
33 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company on a test substance (identified as DuPont-3615) in rabbits, which was completed on December 9, 1999.
|
1999 |
AR226-3138
|
QkBkvMdK5Z9Bygk4MkOkw5q7k |
12 |
|
The document is a confidential report from Elf Atochem S.A. detailing an acute eye irritation study conducted on rabbits using a test substance, with results and evaluations of ocular reactions summarized by the study director, Xavier Manciaux.
|
1999 |
AR226-3137
|
Rp6y11dxz6vqxgw0Z3RBDD47n |
21 |
|
The document is a confidential report from Elf Atochem S.A. detailing an acute oral toxicity study of a test substance in rats, conducted by the Centre International de Toxicologie, with a completion date of December 13, 1999.
|
1999 |
AR226-3139
|
ymLdjjyjv2wbg4V8avnjy0XDn |
24 |
|
The document is a confidential report from Elf Atochem SA detailing an acute dermal irritation study conducted on rabbits to evaluate the effects of a test substance, with the study completed on December 13, 1999, at the Centre International de Toxicologie in France.
|
1999 |
AR226-3140
|
3Q29yJ7z319B9LgOZgDkQjgOa |
24 |
|
The document is a confidential report from Elf Atochem S.A. detailing an acute oral toxicity study of a test substance, likely related to perfluorinated compounds, conducted by the Centre International de Toxicologie, with findings on clinical signs, mortality, and body weight changes in treated rats.
|
1999 |
AR226-3141
|
xzd7JOO7kqo10OMybjyRe8kNE |
24 |
|
The document reports on a study conducted by DuPont evaluating the oral approximate lethal dose (ALD) of a test substance (H-24256) in male rats, finding that the ALD is greater than 11,000 mg/kg with no observed mortality or clinical signs of toxicity.
|
1999 |
AR226-3143
|
2JzyLR85Da8NeKdQmoZLxXaZN |
7 |
|
The document is a confidential study report conducted by Elf Atochem S.A. on the acute dermal irritation of a test substance in rabbits, completed on December 13, 1999, at the Centre International de Toxicologie, detailing the methodology and results of cutaneous examinations.
|
1999 |
AR226-3142
|
d07G3mwZ898RbxODjNLYz9gR |
22 |
|
This document is a toxicity study report by DuPont Specialty Chemicals on the oral administration of a test substance to CD rats for four weeks, conducted by Huntingdon Life Sciences Ltd. and compliant with Good Laboratory Practice standards.
|
1999 |
AR226-3132
|
xOVKyydD856pE10q8jgzj9B1 |
295 |
|
This interim report from 3M Environmental Laboratory details the analysis of perfluorobutanesulfonate (PFBS), perfluorohexanesulfonate (PFHS), and perfluorooctanesulfonate (PFOS) in various environmental samples from Northern Alabama's potable water systems as part of the 3M Decatur Monitoring Program.
|
1999 |
AR226-3798
|
x06O9vX7zX3MkoyG1n7XEExg |
123 |
|
This interim report from 3M Environmental Laboratory details the analysis of perfluorobutanesulfonate (PFBS), perfluorohexanesulfonate (PFHS), and perfluorooctanesulfonate (PFOS) in various environmental samples from Northern Alabama's potable water systems as part of the 3M Decatur Monitoring Program.
|
1999 |
AR226-3828
|
zbvZYrdXrR6bpQ91rRYzLMDD0 |
123 |
|
This is a final field report from Battelle summarizing the multi-city study activities conducted in Mobile, Alabama, and Pensacola, Florida, under Project Number N100672-01, focusing on the collection of samples for trace-level analysis of FC residuals.
|
1999 |
AR226-0677
|
vBG3Y6qVMyvZwxnwDrm11eOe6 |
17 |
|
This is a field report from Battelle (Project Number N100672-01) detailing the multi-city study conducted in Cleveland, Tennessee, and Decatur, Alabama, focusing on the collection of samples for trace-level analysis of specific FC residuals to assess environmental dispersion and human exposure.
|
1999 |
AR226-0678
|
2NavQz3LaZbgmb0qLpvx6YM3N |
16 |
|
This is a final field report from Battelle (Project Number N100672-01) detailing the multi-city study conducted in Columbus, Georgia, and Port St. Lucie, Florida, focusing on the sampling of FOSE-based fluorochemical residuals for environmental and human exposure assessment.
|
1999 |
AR226-0679
|
ypQ95jy3pv2ZvZ6mjDDeE8eod |
16 |
|
The document summarizes a developmental toxicity study of PFOS (Perfluorooctanesulfonate) conducted on pregnant rabbits, which found significant dose-related effects on body weight and food consumption at higher doses, but no teratogenic malformations were observed.
|
1999 |
AR226-0949
|
8RQaD7281Mjp0R58x1YmrqXrB |
295 |
|
The document reports on a developmental toxicity study of N-EtFOSE conducted on pregnant rabbits, finding that while the compound caused dose-related maternal toxicity and increased abortions at higher doses, it was not teratogenic as no malformations were observed in the fetuses.
|
1999 |
AR226-0612
|
575MpRO8Z36BO11LpZzdExE4 |
1 |
|
The document discusses concerns regarding the finalization of a dietary toxicity study report on N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE) conducted by Covance Laboratories, specifically questioning the conclusion of the no observable adverse effect level (NOAEL) being less than 3 ppm due to insufficient evidence of biological significance at that concentration.
|
1999 |
AR226-0612
|
XOOvZQwZbnnanJxjxDZy8J8K4 |
1 |
|
The document is a final pilot report detailing an oral dosage-range developmental toxicity study of N-EtFOSE in rats, conducted by Argus Research Laboratories, Inc. under the direction of Dr. Raymond G. York.
|
1998 |
AR226-0272
|
B236vMERVaD99jVKyDZz6D9w |
112 |
|
This document reports on a study conducted by Wildlife International Ltd. for 3M Corporation to determine the melting point/melting range of PFOS, completed in compliance with Good Laboratory Practice standards.
|
1998 |
AR226-0045
|
B8VV3en1b7o07OeEo9j6Mv6ew |
14 |
|
The document outlines a protocol for determining the melting point/melting range of PFOS (perfluorooctane sulfonic acid, potassium salt) to be conducted by Wildlife International Ltd. for 3M Corporation, following OECD testing guidelines.
|
1998 |
AR226-0046
|
MoBML80JBMY25dnVvDjzQqJv7 |
9 |
|
The document outlines a protocol for determining the vapor pressure of PFOS (perfluorooctane sulfonic acid, potassium salt) using the spinning rotor gauge method, to be conducted by Wildlife International Ltd. for 3M Corporation following OECD testing guidelines.
|
1998 |
AR226-0049
|
LKjXjQvm2xnDody93p0XrzO3w |
9 |
|
The document outlines a protocol for determining the water solubility of PFOS (perfluorooctane sulfonic acid, potassium salt) using the shake flask method, as requested by 3M Corporation and conducted by Wildlife International Ltd.
|
1998 |
AR226-0053
|
G6085webXBKrjbBB2rrKyer9n |
10 |
|
This final report details a 96-hour static acute toxicity test of PFOS conducted on the fathead minnow (Pimephales promelas) by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards despite some exceptions in substance characterization and stability determination.
|
1998 |
AR226-0083
|
LoXy3VMnZYa8dLjqbQnjoxJk3 |
58 |
|
This document is an amended final report on a 96-hour toxicity test of PFOS conducted with the freshwater alga Selenastrum capricomutum, sponsored by 3M Corporation and compliant with Good Laboratory Practice standards.
|
1998 |
AR226-0085
|
5kY60e17ORK94jK69k9r4zZ0R |
75 |
|
The document is an amended final report on a 48-hour static acute toxicity test of PFOS conducted with the cladoceran Daphnia magna, sponsored by 3M Corporation and compliant with Good Laboratory Practice standards.
|
1998 |
AR226-0087
|
oe39jk8NjraxpJJqOX5J1bn8 |
55 |
|
The document is a final report on an activated sludge respiration inhibition test for PFOS conducted by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practices while noting exceptions in substance characterization and stability assessments.
|
1998 |
AR226-0093
|
gDE8J5rVddZgna73y4GD2MRYQ |
63 |
|
The document is an amended final report of a 96-hour static acute toxicity test conducted by Wildlife International Ltd. on PFOS (perfluorooctane sulfonate) using the saltwater mysid (Mysidopsis bahia), sponsored by 3M Corporation, and completed on June 24, 1999, with compliance to Good Laboratory Practice standards.
|
1998 |
AR226-0095
|
n9eyK2wXQM2jgmeL2Mw10BMwa |
58 |
|
The document reports on the estimated boiling point of N-Ethylperfluorooctanesulfonamide (EtFOSA), a substance produced by 3M Company, based on extrapolated data from a vapor pressure study, indicating a boiling point of approximately 423°C at 760 mm Hg pressure.
|
1998 |
AR226-0334
|
Xz4VzEV2Mr26YEyG4O0ajRvJw |
4 |
|
The document reports on a vapor pressure study of N-Ethylperfluorooctanesulfonamide (EtFOSA) conducted by AScI Corporation for 3M Company, indicating a vapor pressure of 0.142 Pa at 20°C, with a noted concern regarding the accuracy of the sample's 99% purity.
|
1998 |
AR226-0335
|
gDdBje6EVKO1zpXz3ozrxBLeJ |
28 |
|
The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the fish species Pimphales promelas, detailing the test conditions and methods used, but does not provide specific results or findings.
|
1998 |
AR226-0337
|
XODe0RzY7dVG88OD174gE3kn4 |
10 |
|
The document reports on an acute toxicity study of N-Ethylperfluorooctanesulfonamide (EtFOSA) on Daphnia magna, detailing the test conditions and methods used to determine lethal loading values and NOEL, with nominal concentrations ranging from 5.8 to 45 mg/L.
|
1998 |
AR226-0338
|
B8LaqLBoE054XV99Y5KmB0oXX |
9 |
|
The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the aquatic invertebrate Ceriodaphnia dubia, detailing the test conditions and nominal loading concentrations used to assess mortality.
|
1998 |
AR226-0340
|
LK4veEgJnqvymEe85bkYv2Vbb |
9 |
|
The document details an activated sludge respiration inhibition test conducted on N-Ethylperfluorooctanesulfonamide (EtFOSA), assessing its impact on dissolved oxygen concentrations using activated sludge from Duluth, MN, with no recorded sample purity or lot number.
|
1998 |
AR226-0342
|
V3D6Zq64G1rkNxKbRyOkV7vDo |
9 |
|
The document reports on the boiling point determination of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) as part of a vapor pressure study conducted by 3M Company in 1998, indicating that the boiling points were extrapolated rather than empirically obtained.
|
1998 |
AR226-0345
|
JvxYJ80E6e5znbop96DBrr82a |
4 |
|
The document reports on a vapor pressure study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating that it is a stable white waxy solid with a purity of 99%, and concludes that the substance would primarily exist in the gas phase in the atmosphere, despite some concerns regarding data reliability and testing deviations.
|
1998 |
AR226-0346
|
MGGBYaa0YVdj1jorZ5ZXVGzEx |
62 |
|
Empty document.
|
1998 |
AR226-0979
|
10GRR3yx0Ge4j6vJXpz9na9mE |
1 |
|
The document outlines the rationale for dose setting in a six-month chronic oral study of PFOS in Cynomolgus monkeys, highlighting a highly linear relationship between cumulative dose and serum concentration, with recommended dose groups of 0.0, 0.02, 0.15, and 0.75 mg/kg/day.
|
1998 |
AR226-0147
|
3x6qvOX1YwKv84gR81OjJ5Ga |
13 |
|
The document is an unaudited draft final report of a 4-week capsule toxicity study on Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) conducted in Cynomolgus monkeys by Covance Laboratories for 3M, adhering to EPA Good Laboratory Practice Standards.
|
1998 |
AR226-0144
|
99bYjEpNe3vb9V73OGQkmmJL6 |
230 |
|
The document is an analytical report prepared for 3M Medical Department detailing the characterization of metabolites T-6292, T-6293, and T-6294 from rat and human hepatocytes, along with a semi-quantitative analysis of T-6295 using LC/MS and LC/MS/MS techniques.
|
1998 |
AR226-0163
|
VGKjryv46QEG14Nrw3De70ZrN |
69 |
|
This is a cover page for a supplement of the journal "Toxicological Sciences," detailing various studies, including one on the cytotoxicity of particulate matter in Puerto Rico and another on the antitumor activities of coumarin and its metabolites.
|
1998 |
AR226-0172
|
mm2p6rrbYb8KZyVLV27LZ785O |
3 |
|
This document outlines a preliminary ADME study of FC-129, sponsored by 3M Specialty Chemicals Division, aimed at assessing the absorption, distribution, metabolism, and excretion of the compound in rats to identify persistent metabolites.
|
1998 |
AR226-0227
|
B87EY6pgVq5ke0MDOvkNE9azm |
1 |
|
The document summarizes a study conducted by the 3M Environmental Lab analyzing endogenous levels of PFOS in the livers of Nave rats from different suppliers, finding measurable PFOS levels in rats from Charles River and Taconic Farms, particularly in older male rats, while no PFOS was detected in Harlan rats.
|
1998 |
AR226-1030
|
xzwXGarVgmM2qZNLB4XNkrO3b |
3 |
|
This document is a final report from 3M Environmental Technology and Safety Services detailing an analytical study on contamination testing conducted by Covance Laboratories, initiated on June 29, 1998, related to perfluorinated compounds.
|
1998 |
AR226-1030
|
91Xb9KYJVXYd7D6p4m2K1BEk6 |
141 |
|
This document is a pathology review assessing tumorigenesis data from a two-year study on the fluorochemical FM-3924, sponsored by 3M, to evaluate its chronic toxicity and carcinogenic potential in rats.
|
1998 |
AR226-0264
|
6Rx36MzXG80gZoXEvXmNrV4V3 |
7 |
|
This document is a final report from 3M Environmental Technology and Services detailing an analytical study on contamination testing conducted by Covance Laboratories, with a focus on assessing the presence of perfluorinated compounds.
|
1998 |
AR226-1030
|
gbNzQ29gzep151B643XrvxXM3 |
141 |
|
The document summarizes a study conducted by the 3M Environmental Lab analyzing endogenous levels of PFOS in the livers of Nave rats from different suppliers, finding measurable PFOS levels in rats from Charles River and Taconic Farms, particularly in older male rats, while no detectable PFOS was found in Harlan rats.
|
1998 |
AR226-1030
|
7RkgwJzL1EJ6KLgmRKO8n72ye |
3 |
|
The document outlines a corporate toxicology study conducted by 3M on FC-129, focusing on its absorption, distribution, metabolism, and excretion (ADME) in rats, with the objective of identifying persistent metabolites.
|
1998 |
AR226-0227
|
peEE4jgaoOE6g9GgLgVnqnxxD |
1 |
|
The document provides an overview of 3M's production of perfluorooctanesulfonyl fluoride (POSF) using the Simons Electro-Chemical Fluorination process, detailing the synthesis method and the chemical's identification.
|
1998 |
AR226-0576
|
wJLGbzEGnyzB5ywkRBX98KBV |
25 |
|
The document provides information about N-Methyl perfluorooctanesulfonamide (MeFOSA), produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its chemical identification, production methods, and distribution estimates.
|
1998 |
AR226-0581
|
QxOREoDdm0XzakX7jMkB6aL6 |
20 |
|
The document provides information about N-Ethylperfluorooctylsulfonamido ethanol (EtFOSE), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and distribution estimates.
|
1998 |
AR226-0582
|
XzJJyyVm1kRrmne2nkOaxL0dw |
24 |
|
The document provides information about N-ethyl perfluorooctanesulfonamido ethyl methacrylate (EtFOSEMA), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and characteristics.
|
1998 |
AR226-0585
|
rx5Gy6aR63a2KMK33Dk88BERq |
20 |
|
The document provides information about N-Methyl perfluorooctanesulfonamidoethyl acrylate (MeFOSEA), a chemical produced by 3M Company using the Simons Electro-Chemical Fluorination process, detailing its synthesis and distribution estimates.
|
1998 |
AR226-0586
|
EdXydwzzvQ3M8zKQNLa0dwx8L |
25 |
|
The document is a meeting request from 3M to the EPA, discussing the company's position on the safety of PFOS levels in human and environmental contexts, asserting that current data do not indicate significant health risks associated with PFOS.
|
1998 |
AR226-0621
|
jmE68mq5O5V4Qq6DN1Nej77Z9 |
2 |
|
This letter from 3M outlines action items agreed upon with the EPA regarding the development of a product stewardship agreement and the provision of health effects information and exposure assessments related to perfluorooctane sulfonic acid (PFOS).
|
1998 |
AR226-0624
|
ZBVVV0n8x1O4ODp0nMmK4xgk7 |
1 |
|
This document is a pathology review assessing tumorigenesis data from a two-year study on the fluorochemical FM-3924, sponsored by 3M, to evaluate its chronic toxicity and carcinogenic potential in rats.
|
1998 |
AR226-0264
|
b5VY6E88Gqv71xzR05eBqB101 |
7 |
|
The document outlines a protocol for determining the melting point/melting range of PFOS (perfluorooctane sulfonic acid, potassium salt) to be conducted by Wildlife International Ltd. for 3M Corporation, following OECD testing guidelines.
|
1998 |
AR226-0046
|
rpdGpJL0OZ3OzKa2D8JOwv6MJ |
9 |
|
The document reports on a study conducted by Wildlife International Ltd. to determine the melting point/melting range of PFOS, sponsored by 3M Corporation, in compliance with Good Laboratory Practice standards.
|
1998 |
AR226-0045
|
rBOaEJaRx4n9m7kbmO1j4KOMV |
14 |
|
The document outlines a protocol for determining the vapor pressure of PFOS (perfluorooctane sulfonic acid, potassium salt) using the spinning rotor gauge method, to be conducted by Wildlife International Ltd. for 3M Corporation in accordance with OECD testing guidelines.
|
1998 |
AR226-0049
|
2Rzq6D9VqBeGDpJe6DvYpEdZN |
9 |
|
The document outlines a protocol for determining the water solubility of PFOS (perfluorooctane sulfonic acid, potassium salt) using the shake flask method, as requested by 3M Corporation and conducted by Wildlife International Ltd.
|
1998 |
AR226-0053
|
MJO3exyg2Eekw59b5qxZDwMpk |
10 |
|
The document is a final pilot report on an oral dosage-range developmental toxicity study of N-EtFOSE conducted in rats by Argus Research Laboratories, detailing the study's purpose, methods, results, and conclusions.
|
1998 |
AR226-0272
|
kDma3byrBzyvjd1jgXbg0ELpE |
112 |
|
The document is a final report on a 96-hour static acute toxicity test of PFOS conducted on fathead minnows (Pimephales promelas) by Wildlife International Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards despite some exceptions in substance characterization and stability determination.
|
1998 |
AR226-0083
|
v69x85ZDk9NVv7JRbqLN98dB8 |
58 |
|
The document is an amended final report of a 48-hour static acute toxicity test conducted by Wildlife International Ltd. on PFOS using the cladoceran Daphnia magna, sponsored by 3M Corporation, and completed on June 4, 1999, with compliance to Good Laboratory Practice standards.
|
1998 |
AR226-0087
|
Bvvwx91vZ2N6MdmzwLMgavVo4 |
55 |
|
This document is an amended final report of a 96-hour toxicity test conducted by Wildlife International Ltd. on PFOS using the freshwater alga Selenastrum capricomutum, sponsored by 3M Corporation, and it outlines compliance with Good Laboratory Practice standards.
|
1998 |
AR226-0085
|
aJbpMM1dDaDJK4GR5nX96872b |
75 |
|
This final report details an activated sludge respiration inhibition test conducted by Wildlife International Ltd. for 3M Corporation, assessing the effects of PFOS, with noted deviations from Good Laboratory Practice compliance regarding substance characterization and stability.
|
1998 |
AR226-0093
|
Lgr7q3k4mGeyRoyYqDam3xyKz |
63 |
|
The document details a toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) using the marine algal species Skeletonema costatum, indicating that the test sample, FC-201AF, consists of 3% PFOS among other components, and outlines the methodology and conditions for assessing algal growth inhibition.
|
1998 |
AR226-0695
|
9Qe3R24wBVvzLqrzoZ0Lqrkq |
34 |
|
The document discusses the rationale for dose setting in a six-month chronic oral study of PFOS in Cynomolgus monkeys, highlighting a linear relationship between cumulative dose and serum concentration, with recommended dose groups of 0.0, 0.02, 0.15, and 0.75 mg/kg/day.
|
1998 |
AR226-0147
|
wrenRLD1Z2LOOjqy1VdoLL1aE |
13 |
|
The document is an unaudited draft final report of a 4-week capsule toxicity study on Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) conducted by Covance Laboratories for 3M, adhering to EPA Good Laboratory Practice Standards.
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1998 |
AR226-0144
|
jgv6kGJKm0ZgERoDp1MrjqV4O |
230 |
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The document details a toxicity test of a mixture containing 1.34% PFOS, conducted using the marine algal species Skeletonema costatum, to assess its impact on algal growth over a 72-hour exposure period.
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1998 |
AR226-0732
|
ypkm7RV9LOGDaOokrmBq3w8OX |
34 |
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The document is an analytical report prepared for 3M Medical Department detailing the characterization of metabolites T-6292, T-6293, and T-6294 from rat and human hepatocytes, along with a semi-quantitative analysis of T-6295 using LC/MS and LC/MS/MS techniques.
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1998 |
AR226-0163
|
82LRXawrwzr60j7jO8az6Nz6K |
69 |
|
This is a cover page for a supplement of the journal "Toxicological Sciences," published by Academic Press in March 1998, containing various studies including those on particulate matter and coumarin's antitumor activities.
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1998 |
AR226-0172
|
LJ3Z3xy6nkB2OQKQy651B97og |
3 |
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The document details a toxicity test of a mixture containing 1% PFOS, conducted using the marine algal species Skeletonema costatum to assess its impact on aquatic plants, following the NS-EN ISO 10253 method.
|
1998 |
AR226-0846
|
GmrqMrnBr4DaeKQNJvzrzk687 |
35 |
|
The document details a toxicity test on a mixture containing perfluorooctanesulfonate (PFOS) using the marine algal species Skeletonema costatum, following the NS-EN ISO 10253 method, to assess its impact on algal growth.
|
1998 |
AR226-0859
|
6X6RXLked1kVGdp0dMrgYLv4 |
34 |
|
The document outlines a study by 3M Medical Department's Toxicology Services to investigate potential sources of low-level perfluorooctanesulfonate (PFOS) contamination in control rats, including contamination from the housing area, feed, and background serum levels, with various study directors appointed for each objective.
|
1998 |
AR226-0960
|
XOL53M8VEoezqzeKQGjKkmYDG |
24 |
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The document reports on the estimated boiling point of N-Ethylperfluorooctanesulfonamide (EtFOSA), a substance produced by 3M Company, based on extrapolated data from a vapor pressure study, indicating a boiling point of approximately 423°C at 760 mm Hg.
|
1998 |
AR226-0334
|
by0g6ko53ppEyKG5qzvXNbQpo |
4 |
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The document reports on a vapor pressure study of N-Ethylperfluorooctanesulfonamide (EtFOSA), conducted by AScI Corporation for 3M Company, indicating a vapor pressure of 0.142 Pa at 20°C, with a noted concern regarding the accuracy of the sample's 99% purity.
|
1998 |
AR226-0335
|
jYxwDvYKbj2wperYdV9QoooQ |
28 |
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The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the fish species Pimphales promelas, detailing the test conditions and methods used, but does not provide specific results or findings.
|
1998 |
AR226-0337
|
vBKpxn30ZppqdDegJaD5pznrw |
10 |
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The document reports on an acute toxicity study of N-Ethylperfluorooctanesulfonamide (EtFOSA) on Daphnia magna, detailing the test conditions, methods, and nominal loading concentrations used to assess lethal loading values.
|
1998 |
AR226-0338
|
baKn03Logp65eMaypNzK589Z1 |
9 |
|
The document reports on an acute toxicity test of N-Ethylperfluorooctanesulfonamide (EtFOSA) on the aquatic invertebrate Ceriodaphnia dubia, detailing the test conditions and methodology used to determine lethal loading values.
|
1998 |
AR226-0340
|
1gVm9B0MVgGzG1nzLOdbE1baK |
9 |
|
The document details an activated sludge respiration inhibition test conducted on N-Ethylperfluorooctanesulfonamide (EtFOSA) to assess its impact on dissolved oxygen concentrations, using activated sludge from Duluth, MN, with results indicating the substance's effects on respiration rates.
|
1998 |
AR226-0342
|
xz58zgVGyo6OrRjG27jeON5YQ |
9 |
|
The document reports the boiling point determination of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) as part of a vapor pressure study conducted by 3M Company in 1998, noting that the boiling point values were extrapolated rather than empirically obtained.
|
1998 |
AR226-0345
|
LgB2DXnr7dGwnaQ55VDNo4bJz |
4 |
|
The document reports on a vapor pressure study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating that it is a stable white waxy solid with a vapor pressure suggesting it would primarily exist in the gas phase in the atmosphere, despite some concerns regarding the purity and data variability.
|
1998 |
AR226-0346
|
Ex13VNk1pv9XY8VME5GRYy0GL |
62 |
|
This document is a final report of a two-generation reproduction study on ammonium perfluorooctanoate (APFO) conducted in rats by Argus Research, sponsored by a company, and completed on March 26, 2002, adhering to EPA Good Laboratory Practice standards with noted exceptions.
|
1998 |
AR226-1092
|
VG9v2MXwmwmV6zqaRznoLR6nq |
1245 |
|
This is a final report on a developmental toxicity study of N-EtFOSE in rats (Sponsor's Study Number: T-6316.7) conducted under Protocol 418-011, dated December 17, 1998.
|
1998 |
AR226-0966
|
yk5nkyG3D8qv4aEqpErwonGQV |
163 |
|
This document outlines a protocol for a 26-week toxicity study of Ammonium Perfluorooctanoate (APFO) in cynomolgus monkeys, sponsored by the APME Ad-Hoc APFO Toxicology Working Group, to evaluate its effects on enzyme levels, hormones, and biochemical parameters.
|
1998 |
AR226-0452
|
pmvreXv2dLYzkJ2q7mBaVE6jD |
18 |