|
This document is an analytical report from Centre Analytical Laboratories detailing the fluorochemical characterization of water and sediment samples, specifically analyzing perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) from 3M's Project E00-2003 in Port St. Lucie, Florida
|
2003 |
AR226-0979
|
KJnM5OzBR9BME8BGj4m6G25RX |
9 |
|
This is a letterhead cover page from 3M Specialty Materials, dated December 22, 2000, with no analytical content retained in the OCR.
|
2000 |
AR226-0979
|
LJZ34NojkJwLNOx3D47gaYjO3 |
7 |
|
The document is a cover letter from Bill Weppner of 3M to Charles Auer at the EPA, submitting various reports related to PFOS, including interim findings on serum half-lives, acute toxicity studies, and genotoxicity assessments.
|
2000 |
AR226-0979
|
DG0DeajeMOVqGYr09NB8eLbdB |
6 |
|
The interim report from 3M Company details a study on the serum half-lives of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) in retired fluorochemical production employees, indicating that PFOS has a half-life significantly lower than previous estimates and that PFOA's half-life is approximately one year.
|
2000 |
AR226-0979
|
Rp39kjj7EVa6bRxxRdD79n1DB |
9 |
|
3M is providing the EPA with additional information on perfluorooctane sulfonates and related compounds, including studies on health effects and environmental science, as part of ongoing discussions regarding fluorochemistry.
|
2000 |
AR226-0979
|
15L6vkZ7oJ9vnw0XDVMJxxXgj |
13 |
|
This memo details the results of pooled human serum samples for PFOS collected from European blood banks in 1999, indicating consistent findings with previous data, with average concentrations of PFOS in Belgium, the Netherlands, and Germany being 17 ppb, 53 ppb, and 37 ppb, respectively.
|
2000 |
AR226-0979
|
qnyLjVkB5yXjVdwJxLgR8BvM |
1 |
|
The document is a draft electron microscopy report detailing the evaluation of liver tissues from cynomolgus monkeys in a 26-week toxicity study of perfluorooctane sulfonic acid (PFOS), indicating that lesions observed during treatment have resolved in recovery animals.
|
2000 |
AR226-0979
|
nkQVenbwyeLyRdO5av37EqGvz |
34 |
|
The document is a supplemental submission detailing ongoing studies, specifically a pharmacokinetic study of perfluorooctanesulfonyl fluoride (POSF) in rats, referenced by 3M.
|
2000 |
AR226-0979
|
b5oqy566rX53KY0xb2Mrk4M86 |
1 |
|
This document is a supplemental submission detailing various studies related to N-ethyl perfluorooctane sulfonamidoethanol (N-EtFOSE) and PFOS, including acute toxicity, pharmacokinetics, and teratology studies conducted by 3M and other laboratories, along with a correction to the indexing of a previous letter.
|
2000 |
AR226-0979
|
Gm7db38g1NrvVO1qKrqg19wMn |
1 |
|
This document is a supplemental submission detailing acute toxicity studies and pharmacokinetic research related to N-EtFOSA (N-ethyl perfluorooctanesulfonamide) and PFOS, including corrections to previously submitted bibliographic entries and ongoing research at the University of Minnesota.
|
2000 |
AR226-0979
|
KR6J71N66rdddazK6gedVz3D6 |
1 |
|
This document is a supplemental submission regarding a pharmacokinetic study of Perfluorooctane Sulfonamide (PFOSA) in rats conducted by 3M, including references to interim reports and pending laboratory findings.
|
2000 |
AR226-0979
|
wgYQ4oZJay10Nyo83BqxpeQeJ |
1 |
|
The document is a supplemental submission regarding PFOSAA (Perfluorooctane sulfonylamido (ethyl)acetate) and includes references to various studies on acute toxicity and serum half-lives related to PFOS, as part of a medical surveillance and epidemiologic assessment.
|
2000 |
AR226-0979
|
XOjvX2bZdzv4Xmxmp1aY7m94R |
1 |
|
The document is a supplemental submission regarding PFOA (Perfluorooctanoic acid) and PFOS (Perfluorooctane sulfonate), detailing findings related to medical surveillance, epidemiology, and acute toxicity from research conducted in 2000.
|
2000 |
AR226-0979
|
vBpXR9mB5Dz5XpLwo4oyqNXbY |
2 |
|
The document is a supplemental submission detailing the fluorochemical characterization of surface water samples from multiple locations, including Columbus, GA, Cleveland, TN, Decatur, AL, Mobile, AL, Pensacola, FL, and Port St. Lucie, FL, conducted by Centre Analytical Laboratories, Inc. and Battelle Memorial Institute, focusing on perfluorinated compounds.
|
2000 |
AR226-0979
|
85y0EKwL53KN9y4wQGYxGvQ2Z |
1 |
|
Pace Analytical Services, Inc. conducted resampling for PFOS, PFOSA, POAA, PFHS, and TFA in Port St. Lucie, Florida, under contract with 3M to confirm baseline data from a previous study conducted in July 1999.
|
2000 |
AR226-0979
|
061emG15Z68DVomj2bJXe0vXJ |
13 |
|
The document summarizes a report by Battelle Memorial Institute estimating the waste streams of PFOS and related sulfonated perfluorochemicals from 3M manufacturing and supply chain facilities, highlighting that the estimates are based on conservative assumptions and questioning the degradation of PFOS, which has not been detected as a degradation product in studies.
|
2000 |
AR226-0979
|
Ve5BwB7e30NywbDXjRm4xjng |
11 |
|
3M submitted new and previously unsubmitted health effects research data on perfluorooctane sulfonates (PFOS) and N-ethyl FOSE, including updated analytical reports from monkey and rat studies, to the EPA as part of their ongoing dialogue regarding fluorochemistry.
|
2000 |
AR226-0979
|
GkryrjGrQ2o7xewX7BM9qVLr |
7 |
|
3M is reporting to the EPA the draft results of a retrospective cohort mortality study of workers at its Decatur, Alabama facility, focusing on perfluorooctane sulfonyl fluoride (POSF)-based production processes, which found no statistically significant elevations in mortality ratios among employees, consistent with previous studies.
|
2000 |
AR226-0979
|
0695Dwpjx7KkxmgKKXOxjnGxd |
2 |
|
3M submitted a TSCA 8(e) notice to the EPA regarding a 2-year rat feeding study on N-Ethyl perfluorooctylsulfonamido ethanol (N-EtFOSE), indicating a statistically significant increase in benign liver tumors in high dose female rats, corroborating earlier findings.
|
2000 |
AR226-0979
|
QJQEpYGLv3RrbN5494vQ0Vaz7 |
2 |
|
The document is a report amendment regarding Protocol 418-009 for a combined oral fertility, developmental, and perinatal/postnatal reproduction toxicity study of N-EtFOSE in rats, indicating a correction to the dosage administration notation without affecting the study results.
|
2000 |
AR226-0979
|
9L4bjrY7BDx6qyv3nB7XgxJw7 |
3 |
|
3M submitted a TSCA 8(e) substantial risk notice to the EPA reporting that a 13-week dietary study on N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE) in rats indicated liver effects and reduced body weights at higher doses, with a no-observable adverse-effect level (NOAEL) identified at 3ppm.
|
2000 |
AR226-0979
|
5Rq92BXk65q5mDD2DOn7yjz5 |
2 |
|
The document is a final report from Covance Laboratories detailing a L5178Y TK +/' Mouse Lymphoma Forward Mutation Assay conducted for 3M, which confirms compliance with Good Laboratory Practice regulations and indicates no deviations that would affect the study's integrity.
|
2000 |
AR226-0979
|
jm1Nxo0EQODgy3bj69Nd5nMgk |
29 |
|
This document is a final report on a 4-week range-finding dietary toxicity study of N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE, T-6314) conducted on rats, sponsored by 3M and performed by Covance Laboratories.
|
2000 |
AR226-0979
|
zQ10XOBZawXbmVmgo7b7QMr6m |
373 |
|
This document is a final report on a 13-week dietary toxicity study of N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE, T-6314) conducted in rats, sponsored by 3M and performed by Covance Laboratories.
|
2000 |
AR226-0979
|
b5rrYK27L1QmKxgQKjB2eOd4y |
560 |
|
Empty document.
|
1999 |
AR226-0979
|
N29adZ719OZ8eM1MrV8Mj8Egb |
5 |
|
This document reports on a six-month study of PFOS effects on cynomolgus monkeys, detailing various health metrics such as TSH, cholesterol, HDL, LDL, and VLDL levels across different test groups.
|
1999 |
AR226-0979
|
Ex58nBVqmYqga0J6oO4xyQOqx |
11 |
|
This document outlines a pharmacokinetic study of perfluorooctane sulfonyl fluoride (POSF) in male Sprague Dawley rats, aiming to assess its oral absorption, clearance, and metabolism to PFOS, conducted by 3M Chemicals Division under GLP conditions.
|
1999 |
AR226-0979
|
Gmbw0VQwkdG9DRpJz8X0bbwZ4 |
7 |
|
The document is a field report detailing the multi-city study conducted by Battelle in Cleveland, Tennessee, and Decatur, Alabama, focusing on the sampling and analysis of perfluorinated compounds, including PFOA and PFOS, with results and observations from the study period in May 1999.
|
1999 |
AR226-0979
|
gbwNEmEYVdvkg5RJDYqwyzOkq |
16 |
|
This is a final field report prepared by Battelle for Project Number N100672-01, detailing the multi-city study activities conducted in Mobile, Alabama, and Pensacola, Florida, aimed at assessing environmental exposure to FC residuals.
|
1999 |
AR226-0979
|
wDQazkj2E5oVknGoKrKyVZYRD |
17 |
|
The document is a final field report detailing the sampling activities conducted by Battelle in Columbus, Georgia, and Port St. Lucie, Florida, aimed at collecting representative samples for trace-level analysis of perfluorinated compounds, including PFOA and PFOS.
|
1999 |
AR226-0979
|
bv9MkZRN1mVGqr9yn5eQ5yYO |
16 |
|
Empty document.
|
1998 |
AR226-0979
|
ykjwGZJavzZr44eK2ZaDYK3D |
1 |
|
Empty document.
|
1998 |
AR226-0979
|
10GRR3yx0Ge4j6vJXpz9na9mE |
1 |
|
The document is a final report on a single-dose intravenous pharmacokinetic study of T-6684 in rabbits, sponsored by 3M, conducted by Corning Hazleton, with a completion date of December 31, 1997.
|
1997 |
AR226-0979
|
J3N7JRea9MVrGJr82y60zQYev |
36 |
|
The document is a final report from Covance Laboratories detailing a 5-daily dose dermal absorption/toxicity study of the substance T-6684, sponsored by 3M, conducted on rabbits, with a completion date of December 31, 1997.
|
1997 |
AR226-0979
|
3QZD5bQ4LyVLozmDmNO1xYLK0 |
53 |
|
The document is a final report on a mutagenicity test conducted by Coming Hazleton Inc. for 3M, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells, with compliance to Good Laboratory Practice regulations and no significant deviations reported.
|
1996 |
AR226-0979
|
MobK1Q4QXdmR7yzn89E4e0JEx |
41 |
|
The document is a final report on a mutagenicity test of a substance identified as T-6358 conducted by Corning Hazleton Inc. using an in vivo mouse micronucleus assay, submitted to 3M, and completed on May 14, 1996, confirming compliance with Good Laboratory Practice regulations.
|
1996 |
AR226-0979
|
71BpL02Ob0EEZ7R00k5kjmgoj |
36 |
|
The document is a final report on a single-dose intravenous pharmacokinetic study of T-5904, a compound sponsored by 3M, conducted by Hazleton Wisconsin, Inc. on rabbits.
|
1994 |
AR226-0979
|
ExEKE5zN2qYBryaVEgQVbM7MR |
24 |
|
The document is a final report of a rat teratology study (Project No. 154-161) conducted by Hazleton Laboratories America Inc. for 3M Company, focusing on the effects of a perfluorinated compound on fetal development, with quality assurance inspections and findings documented throughout the study.
|
1984 |
AR226-0979
|
8RbM0Q7qzBnJz6J5bVgMRoo8B |
76 |
|
The document reports on a study conducted by Riker Laboratories, Inc. from October 1980 to June 1981, focusing on the metabolism of carbon-14 labeled N-Ethyl FOSE, a perfluorinated compound, in animal subjects, detailing methods of dosing, sample collection, and radiometric analyses.
|
1983 |
AR226-0979
|
GKz8daLLbMwG6n9b0RprKnkN4 |
21 |
|
The document is a final report of a pilot rat teratology study (Project No. 154-159) conducted by Hazleton Laboratories America, Inc. for 3M Company, focusing on the effects of a test compound on maternal and fetal outcomes.
|
1983 |
AR226-0979
|
DGxkdbpaL3Jeo8ggpYM76YD9n |
50 |
|
The document is a letter from Dr. E. Marshall John to Dr. Franklin D. Griffith stating that FC143, a substance tested in developmental toxicology studies on pregnant rats and rabbits, poses no hazard to the conceptus and does not require further testing.
|
1982 |
AR226-0979
|
jygwKE8njNaEMaaLe04axKXGR |
1 |
|
The document outlines health evaluations conducted in 1981 for 264 employees at Chemolite, including comparisons of testing data with blood fluorine levels as part of the fluorochemical program, with results to be reported later.
|
1982 |
AR226-0979
|
qqdx7wEQeO7LnvVBvoxRGqkx |
1 |
|
The document reports on an acute ocular irritation test of the substance T-2997CoC conducted on female albino rabbits at Riker Laboratories, revealing that it caused severe irritation and various ocular effects after brief contact.
|
1981 |
AR226-0979
|
7MzZDQzKDMGBd5JJKQkEgoqZe |
17 |
|
The document is a final report from SRI International assessing the mutagenic activity of 3M Company's Compound T-2997CoC using the Ames Salmonella/microsome assay and Saccharomyces cerevisiae D3, concluding that the compound was not mutagenic or recombinogenic in any of the assays performed.
|
1981 |
AR226-0979
|
MMnY8Ly638a0KVNxpxN6pGvj9 |
17 |
|
The document reports on an acute oral toxicity study of the substance T-30670OC conducted on albino rats, indicating that the approximate oral LD50 is greater than 5,000 mg/kg, with no observed mortalities or adverse effects during the observation period.
|
1981 |
AR226-0979
|
DvdyRdz7OOjoMbzY04D6wnzmo |
8 |
|
The document reports that SRI International conducted in vitro microbiological mutagenicity assays on 3M Company's Compound T-2816CoC, finding it to be non-mutagenic and non-recombinogenic in various strains of Salmonella typhimurium and Saccharomyces cerevisiae.
|
1980 |
AR226-0979
|
dYEJ94exLR3ynX8G62oxLmoLB |
14 |
|
The document reports on a 28-day percutaneous absorption study of FC-98, a perfluorinated compound, conducted on albino rabbits at Riker Laboratories, which found no adverse effects but indicated dermal absorption potential that could not be conclusively determined due to limited sample analysis.
|
1979 |
AR226-0979
|
b5OGK6Lok9Ym2Q172wXz1ObYD |
16 |
|
This analytical report from Centre Analytical Laboratories details the fluorochemical characterization of surface water samples from Decatur, Alabama, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
1979 |
AR226-0979
|
2qm8eRLLQkY2RNkGLkrdd1eo5 |
7 |
|
The document discusses the results of a rat toxicity study on FC-143, indicating that male rats accumulate approximately 100 times more FC-143 in their livers compared to female rats, with specific liver concentration measurements provided.
|
1978 |
AR226-0979
|
DmgK8j4KDBvV4r0yZ1Zb82Na |
1 |
|
The document summarizes the findings of a medical surveillance program conducted by 3M for employees at the Cottage Grove manufacturing facility from 1978 to 1991, which monitored health indicators and organic fluorine levels in relation to PFOA exposure, with no abnormalities linked to fluorochemical exposure reported by company physicians.
|
1978 |
AR226-0979
|
Z4QOJad2wrxvrjpGqRdvkY608 |
1 |
|
The document reports on an acute oral toxicity study of the test material FM-3422, produced by 3M Company, which found LD50 values of 1615 mg/kg for male rats and 1333 mg/kg for female rats.
|
1978 |
AR226-0979
|
kYqLwoNRVVOZaYwbxzbYbnkn |
13 |
|
The document outlines a protocol for a Rat Teratology Study (Segment II) to assess the embryo/fetal toxicity and teratogenic potential of the test material T-3352, administered to pregnant rats during fetal organogenesis, in compliance with FDA guidelines.
|
1978 |
AR226-0979
|
Znv32VY06Epwyjq22rV1jZMyL |
13 |
|
The document reports on reverse mutation studies conducted on a sample identified as T-1485 from 3M Company, evaluating its mutagenic activity using Salmonella and Saccharomyces strains with and without mammalian metabolic activation.
|
1976 |
AR226-0979
|
70pKZ831Vd5Rw8K296nRe7bqj |
9 |
|
The document discusses the results of skin and eye irritation assessments conducted on FC-95 (T-1117) by the WARF Institute, indicating that the substance was non-irritating to the skin but minimally to mildly irritating to the eyes of albino rabbits, with recommendations for precautionary labeling.
|
1974 |
AR226-0979
|
mVXd782bDbenQnx6kjzXG23Z |
7 |
|
This analytical report from Centre Analytical Laboratories, Inc. details the fluorochemical characterization of surface water samples collected in Cleveland, Tennessee, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide, and perfluorooctanoate, as requested by 3M Environmental Laboratory.
|
1973 |
AR226-0979
|
2NjZQDkqQ66k1v0qLmaxgv36N |
8 |
|
The document summarizes the results of acute toxicity studies conducted by Hazleton Laboratories on T-l*101, a fluorochemical surfactant produced by 3M, indicating that it is slightly toxic when administered orally to rats and practically non-toxic via dermal exposure in rabbits.
|
1908 |
AR226-0979
|
N2ymR2VdZ9qGDdqkoXGg8Nvjb |
3 |
|
Empty document.
|
— |
AR226-0979
|
QgKjLwB96VgRo3eO84x80kgJ7 |
1 |
|
Unreadable document.
|
— |
AR226-0979
|
r0MozaRr4o73YRynwp3MOMxG |
1 |
|
Empty document.
|
— |
AR226-0979
|
717gnJkwR4ZbO5x1qBQNKpGZE |
1 |
|
Empty document.
|
— |
AR226-0979
|
GKkQK4ejK81QEz02YJMJZQ1mV |
1 |
|
Empty document.
|
— |
AR226-0979
|
3e4EKM7K7G7wKKYG5Me8padL6 |
1 |
|
Empty document.
|
— |
AR226-0979
|
91qkpGnV4O469Kzb06Oz5MGpL |
1 |
|
Empty document.
|
— |
AR226-0979
|
yx3ZbEVaxYwpLyamez09r8Qn |
1 |
|
Empty document.
|
— |
AR226-0979
|
b5pqjO9wmz7aDyLMRKx4q08QO |
1 |
|
This is a notice from 3M regarding the submission of documents to the EPA related to fluorochemistry, emphasizing that the documents are for read-only purposes and that discrepancies between digital and paper copies will be resolved in favor of the paper copies.
|
— |
AR226-0979
|
aD9vvdBwZbQGOj6bX6692nv4R |
1 |
|
Empty document.
|
— |
AR226-0979
|
v9d0eV6R7o4ponLwVMRqrgYE |
1 |
|
Unreadable document.
|
— |
AR226-0979
|
Mo76zJ6r28g1J3B7gga83LBBL |
1 |
|
Empty document.
|
— |
AR226-0979
|
mb9LpwZba55OqxQw1kr9agkBZ |
1 |
|
Empty document.
|
— |
AR226-0979
|
KKm3Vz8Xab4wwVGBLbXb9pmK |
1 |
|
Empty document.
|
— |
AR226-0979
|
xzEjX1a19OqKE4dyLMKY6vJbG |
1 |
|
Empty document.
|
— |
AR226-0979
|
3en6b3dnXXVR7rGmkE0KxkzM3 |
1 |
|
Empty document.
|
— |
AR226-0979
|
Yj4bj1X0Xp01QrZnk2LZKkGyE |
1 |
|
Empty document.
|
— |
AR226-0979
|
M31K12awgvm1qy9x04DamyxV |
1 |
|
This is a notice from 3M regarding the submission of documents to the EPA related to fluorochemistry, emphasizing the importance of maintaining the integrity of the original documents.
|
— |
AR226-0979
|
QRN6KzENBKeEExdG60JYYKVv |
1 |
|
Empty document.
|
— |
AR226-0979
|
V35qdMkoL8z8m8JEj1bQBmmQq |
84 |
|
This master's thesis by Deanna J. Nabbefeld investigates the binding effects of perfluorooctane sulfonic acid (PFOS) and other fluorocarbons on liver fatty acid-binding protein (L-FABP), finding that PFOS significantly decreases the binding capacity of L-FABP in treated rats.
|
— |
AR226-0979
|
kppe37w8L8yYM7N33o7LxNYE |
55 |
|
The document is a final report from Hazleton Laboratories America Inc. detailing an eye irritation study conducted on rabbits using the test material T-4016, which is a thick brown liquid, to assess its potential irritative effects according to EPA guidelines.
|
— |
AR226-0979
|
pBQLGx0o5yRajvqLqV2jQL80d |
13 |
|
The document is a final report from Hazleton Laboratories America, Inc. detailing an acute oral toxicity study conducted on rats using a test material identified as T-4016, in accordance with EPA guidelines for testing pesticides and toxic substances.
|
— |
AR226-0979
|
29D3emJjMgXBBpxnwpymX0dp |
9 |
|
The document is a report from Hazleton Laboratories detailing a primary dermal irritation study conducted on rabbits using the test material T-4016, which is associated with the evaluation of skin irritation levels under occluded conditions as per federal regulations.
|
— |
AR226-0979
|
EvbqBNxVaGOpgyqa96LN5dqag |
7 |
|
The document outlines a pharmacokinetic study protocol by 3M to assess the oral absorption, clearance, and biological persistence of Perfluorooctane Sulfonamide (PFOSA) in male Sprague Dawley rats, with a focus on determining the potential conversion of PFOSA to its metabolite PFOS.
|
— |
AR226-0979
|
o9g5OXkm01r5xV8J8Rm3y3kR7 |
10 |
|
The document is a phone conversation report regarding toxicity testing of a sample (T-4101) related to 3M, specifically detailing various OECD toxicity tests including acute oral and dermal toxicity, and primary dermal and eye irritation assessments.
|
— |
AR226-0979
|
DjZVbaV314rwwa9MmNB4nKe5 |
2 |
|
The document is a final report detailing an acute oral toxicity study conducted on rats using the test material T-4101, which is associated with Minnesota Mining & Manufacturing, following OECD guidelines.
|
— |
AR226-0979
|
J3N7qEOk4rMY1MM5kg6M4K5KZ |
17 |
|
The document outlines an acute dermal toxicity study conducted on the chemical T-4101, which is associated with Minnesota Mining and Manufacturing, following OECD guidelines to assess its potential toxicity and skin irritation effects.
|
— |
AR226-0979
|
wR3gyoeqymavx9DvyG357XV6 |
15 |
|
The document is a final report detailing a primary dermal irritation/corrosion study of the test substance T-4101, conducted on rabbits according to OECD guidelines, with the objective of assessing skin irritation potential.
|
— |
AR226-0979
|
qpRYx7KGk7rqm9Qpawwer6EG |
9 |
|
The document is a final report from Minnesota Mining & Manufacturing Company detailing a primary eye irritation/corrosion study conducted on rabbits using the test material T-4101, which is described as a clear yellow liquid, to determine its ocular irritative potential according to OECD guidelines.
|
— |
AR226-0979
|
pBkg74mYNoErM95p0RQBR3KRj |
14 |
|
The document is a final report from Hazleton Laboratories detailing a primary dermal irritation/corrosion study on a test material identified as T-4416, conducted on rabbits according to OECD guidelines, with the objective of assessing skin irritation levels.
|
— |
AR226-0979
|
KGNV8Jgo3vaxpN21Zvo9vbM8Q |
9 |
|
The document is a final report detailing an acute oral toxicity study in rats for a test material identified as T-4416, conducted by Hazleton Laboratories for 3M, which follows OECD guidelines.
|
— |
AR226-0979
|
R6DqQv6DMqGrv4KKZD855Lm7 |
22 |
|
The document is a final report detailing an acute toxicology study on a test substance (T-4416) assessing ocular irritation/corrosion in rabbits, conducted by Hazleton Laboratories for 3M Toxicology Services.
|
— |
AR226-0979
|
0qbaKz4gnbLX78BY6X54ryOok |
17 |
|
The analytical report from Centre Analytical Laboratories details the detection of PFOS and PFOSA in surface water samples collected from Columbus, GA, with PFOS concentrations ranging from 55.4 to 83.3 ng/L and PFOSA reported as estimated values below the reporting limit.
|
— |
AR226-0979
|
nekk2GqxEV58Jwnd8BzxLe2X |
10 |
|
The document is an analytical report from Centre Analytical Laboratories, Inc. detailing the fluorochemical characterization of surface water samples collected from Mobile, Alabama, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC
|
— |
AR226-0979
|
xzVBNN2jZk61k1m5Eq3kQ5bxb |
8 |
|
This analytical report from Centre Analytical Laboratories details the fluorochemical characterization of surface water samples collected from Pensacola, FL, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
— |
AR226-0979
|
kmwDJQ64EzaMKN0R3YRyQmv3b |
8 |
|
This analytical report from Centre Analytical Laboratories details the characterization of surface water samples from Port St. Lucie, FL, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
— |
AR226-0979
|
ByaJm6vm0Ox1YLwvBwkRv401w |
6 |
|
This technical report summarizes the analysis of FC-95 levels in the serum and livers of monkeys from the IRDC subacute toxicity study 137-092, which was initiated after a previous study resulted in the death of all subjects due to incorrect feeding levels.
|
— |
AR226-0979
|
V3aRoj85kkkeR7vyOoVx5oX4g |
3 |
|
The document summarizes a technical report on the analysis of FM-3422 (a perfluorinated compound) in the serum and livers of monkeys from a subacute toxicity study, detailing the determination of its levels and metabolism.
|
— |
AR226-0979
|
QQ0J8QDJbbRY9db7M0MOXpk |
4 |
|
This laboratory report details a pharmacokinetic study of PFOSA conducted by 3M, revealing that PFOS and PFOSA were detected in the livers of all dosed rats, with PFOS levels peaking on day 4 and PFOSA levels decreasing significantly by day 29.
|
— |
AR226-0979
|
bB8jaDrYOX0bMzV9DoV40J6JZ |
328 |
|
The document is an analytical report from the 3M Environmental Laboratory detailing the presence and concentration of PFOS, M556, PFOSAA, and PFOSA in the liver and sera of rats exposed to N-Ethylperfluorooctane sulfonamido-ethanol, conducted under Good Laboratory Practice regulations.
|
— |
AR226-0979
|
JJXagqzy6gvqnDyGrGrqXvYK2 |
130 |
|
This document is an analytical laboratory report from 3M detailing the determination of perfluorooctanesulfonate (PFOS) concentrations in liver and serum samples from a 26-week toxicity study conducted on cynomolgus monkeys, adhering to EPA Good Laboratory Practice standards.
|
— |
AR226-0979
|
LpYbdDBxMajQ8ONrd5rZDdgYq |
232 |