|
The document discusses the evaluation of eight-hour and annual mean C-8 (perfluorooctanoic acid, PFOA) concentrations resulting from emissions at the TFE and FEP buildings of E. I. Du Pont de Nemours & Company, based on five years of hourly meteorological data.
|
1981 |
AR226-1986
|
6bnjwokKMnV9YKY4M84yRw4V1 |
2 |
|
This is a cover page from E. I. du Pont de Nemours & Company regarding an administrative report (AR226-2137) related to various locations at the Washington Works facility.
|
1981 |
AR226-2137
|
Exo3naZQ9D1ROKyxykpJ4veYx |
2 |
|
The document discusses the determination of eight-hour time-weighted average C-8 (perfluorooctanoic acid) concentrations downwind of various emission sources at the DuPont Washington Works facility, specifically focusing on emissions from the FEP and TFE buildings.
|
1981 |
AR226-2136
|
NGk8myD09oDYwQMeK86xq3g1R |
3 |
|
The document discusses concerns from E. I. du Pont de Nemours & Company regarding low exhaust stack heights for C-8 (perfluorooctanoic acid, PFOA) emissions, indicating potential recycling of exhaust back into the building and presenting recent sampling results with safety factors applied for dispersion calculations.
|
1981 |
AR226-2138
|
DvNdQ4O6y0Rxq5oQ6R5QwnLNn |
3 |
|
This document discusses the evaluation of C-8 (PFOA) emissions from the TFE and FEP buildings at E.I. Du Pont de Nemours & Company, detailing calculations of eight-hour and annual average concentrations based on five years of meteorological data, with findings indicating that emissions from the FEP area are negligible compared to other sources.
|
1981 |
AR226-2140
|
x5Lg8RdpYOzKa93xaDNzJEd01 |
2 |
|
The document outlines dispersion calculations for PFOA emissions from a facility, specifying the need for annual average and highest 8-hour average concentration assessments at various receptor locations, based on weather data and operational scenarios.
|
1981 |
AR226-2139
|
37mY5YvLp36BqGGGJZJRp4bp6 |
2 |
|
The document reports on ground-level concentrations of C-8 (perfluorooctanoic acid, PFOA) at the Washington Works facility, indicating that annual mean concentrations are well below the provisional acceptable exposure limit (AEL) of 10 µg/m³, with the highest concentration being only about 5% of the AEL.
|
1981 |
AR226-2141
|
om4yNR8earMoLopwG53vLy5MR |
2 |
|
The document discusses the analysis of effluent streams from the FEP plant related to Project 8533, highlighting discrepancies in fluoride ion content in coagulator effluents, which were found to be ten times higher than expected, suggesting that these results should be discarded.
|
1981 |
AR226-2380
|
Xv6jrX7Dkg4ojD7k6Z3Gb8DJ |
3 |
|
The document reports on a liver study of Washington Works employees exposed to perfluorooctanoate (C-8), indicating that while initial biochemical data suggested potential liver damage, further analyses did not provide conclusive evidence of occupationally related health problems among the workers.
|
1981 |
AR226-2761
|
ymgmQBw7Q9k6kZgeq5YroyMXn |
26 |
|
This document is a final report on a study conducted for E.I. DuPont to evaluate the embryofetal toxicity and teratogenicity of perfluorobutylethene (PFBE) in pregnant rats, which found no adverse maternal effects at low doses, but significant reductions in body weight gain and food consumption at high doses.
|
1981 |
AR226-2773
|
qk17mQ15zzwg87oOGEap5ZbBq |
48 |
|
This document is a quality assurance report for a study conducted by DuPont on the embryo-fetal toxicity and teratogenicity of ammonium perfluorooctanoate (C-8) in rats, detailing the audit findings from October 1981.
|
1981 |
AR226-2775
|
zzaqGjq2RK8J0K6n2EOyKnvvz |
60 |
|
The document outlines a study conducted by E.I. DuPont de Nemours & Co. to monitor levels of the surfactant FC-143 (ammonium perfluorooctanoate) in the workplace and environment due to potential health concerns, with objectives including measuring personnel exposure and developing accurate detection methods.
|
1981 |
AR226-3334
|
GKM50XDGzmBEzqzrj70N2Lbx4 |
29 |
|
The document provides a summary of the toxicity and human exposure studies related to Ammonium Perfluorooctanoate (C-8), also known as PFOA, highlighting its moderate acute toxicity, irritation effects, and long half-life in humans, with blood levels observed in occupationally exposed workers.
|
1981 |
AR226-3374
|
NNaqae4xXQr0jxpa7nz2bdZER |
6 |
|
The document details a biodegradation test (OECD 301E) conducted on a mixture containing 1.34% PFOS, prepared by 3M, indicating that the data may not accurately reflect the degradation potential of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1981 |
AR226-0711
|
44YMjYaMVmYVvKjy6z6XMZwk1 |
20 |
|
The document details a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) using a modified OECD 301E method, indicating that the test sample was a mixture with 1.34% PFOS and various other components, although the results may not accurately reflect the degradation potential of PFOS due to incomplete characterization of impurities.
|
1981 |
AR226-0737
|
6bp8owy21rgra9nK8L2R8vjqE |
57 |
|
The document summarizes multiple biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) in the product FC-203C, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but concludes that no reliable conclusions can be drawn due to variability in results and methods used.
|
1981 |
AR226-0741
|
MMeKJJgvXOnnOLeYzYY5vbLx |
18 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing perfluorooctanesulfonate (PFOS) from the FC-203C production lot, indicating that the test sample's impurities may affect the accuracy of toxicity data.
|
1981 |
AR226-0742
|
ExGa6ng2MDexkqj23NVJo9ad4 |
14 |
|
The document details a toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M on the aquatic plant species Selenastrum capricomutum, using a 96-hour acute static method to assess algal cell counts and dry weights.
|
1981 |
AR226-0744
|
ZBz61BMxM9BojD5oxL041rYzO |
10 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic invertebrate Daphnia magna, indicating that the test sample was a complex mixture with unspecified concentrations and impurities, which may affect the interpretation of toxicity results.
|
1981 |
AR226-0745
|
6bXqva8p9Ye7x4MekvyX2LVg1 |
3 |
|
The document details an activated sludge respiration inhibition test conducted by 3M on a mixture containing perfluorooctanesulfonate (PFOS) to assess its toxicity, noting the composition of the test sample and the methodology used.
|
1981 |
AR226-0746
|
MJ0V1YKNN57gq5b4JzBon5Vna |
5 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 0.73% PFOS, conducted by 3M, which found no acute inhibitory effect on activated sludge respiration rate at a concentration of 1,000 mg/L.
|
1981 |
AR226-0802
|
2RmzDQ0BvNK4KkxaEVLz91jEr |
6 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.73% PFOS, assessing its effects over a 96-hour exposure period, although the test's GLP compliance and specific fish age were not noted.
|
1981 |
AR226-0803
|
e7kOLQZ46Y8ndLN243rdqLZxp |
14 |
|
The document reports on biodegradation studies of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that while the majority of the product components appear to be readily biodegradable, no reliable conclusions can be drawn from the data due to the presence of impurities.
|
1981 |
AR226-0801
|
6BaEGVXBgKkwVyrEdVpgd2Lb6 |
18 |
|
This document details a toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the algal species Selenastrum capricomutum, using a 96-hour exposure period to assess algal cell counts and dry weights.
|
1981 |
AR226-0805
|
YjBbBvVQBMwyB2oDerxjqnEXy |
10 |
|
The document reports on a biodegradation test conducted by 3M Company on a mixture containing perfluorooctanesulfonate (PFOS), revealing high biochemical oxygen demand (BOD) values but lacking reliable data quality due to incomplete characterization of the test substance and its impurities.
|
1981 |
AR226-0898
|
dn3wBo9VEx83EQRE36mBqgLg6 |
9 |
|
This document reports on an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 6% perfluorooctanesulfonate (PFOS) and various other components, indicating the test was completed in 1981 without GLP compliance.
|
1981 |
AR226-0901
|
ypqgLmvdDMq43NNzOGRYEy5oD |
4 |
|
The document details an acute toxicity test of a PFOS-containing mixture (6% PFOS) on the aquatic invertebrate Daphnia magna, conducted by Rand McNeilly in 1981, using a static exposure method over 48 hours.
|
1981 |
AR226-0902
|
wqdxYJXxVNDxzK3pg5VKmXn4o |
5 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 6% PFOS, conducted by 3M, which found no inhibition of activated sludge respiration at a concentration of 1000 mg/L.
|
1981 |
AR226-0903
|
GmD64npbeaK10a39vOqnrzVQr |
4 |
|
Du Pont reassigned about 50 women workers at its Parkersburg, West Virginia plant after learning that the chemical FC-143, produced by 3M and linked to birth defects in rats, may pose risks to pregnant employees.
|
1981 |
AR226-1328
|
mVydqxNZMbm16vXyxRQzKOEJ |
1 |
|
A preliminary study indicated that the chemical FC-1-43, used at the Du Pont Company plant, may cause birth defects, leading to the transfer of about 50 women workers to new jobs to avoid potential risks.
|
1981 |
AR226-1329
|
wrL2D49xgp4ZEzgyqJbmxMREo |
1 |
|
This letter from E.I. du Pont de Nemours & Company informs the West Virginia Division of Water Resources about toxicity information regarding ammonium perfluorooctanoate (FC-143), a surfactant used in fluoropolymer resin manufacturing, which has shown potential adverse effects on unborn rats in preliminary studies conducted by 3M, prompting Du Pont to reassign female employees of childbearing
|
1981 |
AR226-1330
|
o9g2MqK16wwoj9zkyY94LJmeD |
1 |
|
This memo from DuPont discusses a change in the analytical test method for measuring C-8 (PFOA) in blood samples of personnel, indicating that the new gas chromatography method provides results approximately 282% higher than the previous method.
|
1981 |
AR226-1565
|
LK6obJzvEzV5R1ENyZ8o1ZrLb |
1 |
|
The document outlines a blood sampling program for employees exposed to C-8 (PFOA) to analyze organic fluorine levels and determine the elimination rate of C-8 from the body, specifically targeting female employees who have worked with TEFLON.
|
1981 |
AR226-1563
|
4J22VXEenbq6kjK904p71zRnx |
1 |
|
The document discusses ongoing blood level testing for C-8 (perfluorooctanoic acid, PFOA) among exposed employees and controls, noting that controls have shown non-detectable levels, while an animal study has been initiated to determine a "no-effect" level in rats.
|
1981 |
AR226-1568
|
mBL6Lje3rm7QL1jEqXyjxxrXb |
1 |
|
The document reports the analysis of a blood sample for perfluorooctanoate (PFOA) conducted by DuPont, revealing a concentration of 0.17 ppm F, with details on the analytical method and precision.
|
1981 |
AR226-1592
|
gDagROd5yZypx1eEk3jQ26dXL |
1 |
|
The document presents analytical results for FC-143 (Ammonium Perfluorooctanoate) in blood samples from polymer product workers at Chambers Works, indicating a range of concentrations from 0 to 0.250 with an overall mean of 0.049.
|
1981 |
AR226-1597
|
6wEZ618kJY3XxbKDj0r0Zz0vd |
1 |
|
The document details analytical results for FM-3924, a perfluorinated compound, in corn oil samples submitted for a rat feeding study, indicating low solubility and potential crystallization issues that could affect the study's outcomes.
|
1981 |
AR226-0612
|
ZJ9nbomvwLjmnndRoz84QJe70 |
1 |
|
The document reports on the analytical results of four corn oil samples containing varying concentrations of FM-3924, indicating that while the samples showed good reproducibility and were within 10% of target concentrations, the low solubility of FM-3924 could lead to crystallization issues that may affect a rat feeding study.
|
1981 |
AR226-0612
|
dYObqmgYEjBZeqrZo2jBwZLdb |
1 |
|
The document discusses the comparison of two N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0277
|
3emNzbvOnEM10pReogR7vDOBE |
1 |
|
The document reports on an oral teratology study of FM-3422, a compound found to be teratogenic in pregnant Sprague-Dawley rats, causing developmental abnormalities such as eye defects, cleft palates, and skeletal malformations at various doses, while not affecting embryonic viability or the reproductive health of the dams.
|
1980 |
AR226-0280
|
gbMdLJRJLyy0xDxa4VMBLKyw9 |
26 |
|
The document compares two formulations of N-EtFOSE Alcohol (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0281
|
8522NRD9Rx8modkE22joBzkko |
1 |
|
The document compares two formulations of N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0284
|
daQR524LnKj0Je9qp39Jdg87G |
1 |
|
The document reports on an oral teratology study of FC-95, sponsored by 3M, which found that administration of FC-95 to pregnant rats resulted in teratogenic changes in the lens of the eye, particularly at a dose of 10 mg/kg/day, while showing no embryotoxic effects or significant maternal toxicity at lower doses.
|
1980 |
AR226-0016
|
ppnMjNY2DjO9vVdGM1njy06Rk |
33 |
|
The document reports on a pilot photolysis study conducted by 3M to investigate the degradation of the compound FM-3925 in aqueous solutions when exposed to natural sunlight over nearly seven months, indicating potential isomerization as detected by GC/MS analysis.
|
1980 |
AR226-1030
|
3NJYwonGzv8dmEMwnYaoG3BvD |
9 |
|
The document is a technical report summarizing the investigation into the photolysis of FM3925, a fluorochemical, to determine its degradation in aqueous solutions and identify the major products formed during the process.
|
1980 |
AR226-1030
|
1QLrQkkG3aw82bMkm6XRG8rYq |
22 |
|
The document reports that SRI International conducted in vitro microbiological mutagenicity assays on 3M Company's Compound T-2816CoC, finding it to be non-mutagenic and non-recombinogenic in various strains of Salmonella typhimurium and Saccharomyces cerevisiae.
|
1980 |
AR226-0979
|
dYEJ94exLR3ynX8G62oxLmoLB |
14 |
|
The document describes a compound-specific method developed by 3M Environmental Laboratory for the quantitative characterization of organic fluorochemicals, including PFOA and PFOS, in biological matrices using negative ion electrospray tandem mass spectrometry, aimed at improving detection and analysis of these compounds in humans and the environment.
|
1980 |
AR226-0191
|
373dRRqELxvwBNRLjNqJOMRo0 |
22 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture of decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2151) produced by 3M, with the study following ASTM E729-80 standards and measuring various water quality parameters over a 96-hour exposure period.
|
1980 |
AR226-1030
|
dQeMB3q56oQ1Z1Gp1Zrdvp3dR |
3 |
|
The document reports that the distribution coefficient for decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2070) is 0.65, based on a study conducted by 3M Company using a method to analyze the substance's solubility in n-octanol and water.
|
1980 |
AR226-1030
|
zQ05MkdznydbxOpjnpD88EZQm |
2 |
|
The document reports on a photodegradation study of N-methylperfluorooctane sulfonamidoethanol (FM-3925), conducted using modified Crosby and Tang photoreactors, which found no degradation of the substance after 30 days in deionized water, with potential photolysis products identified but minimal volatilization observed.
|
1980 |
AR226-1030
|
VJLoRqRoQVj18DrZYKvjw8zej |
2 |
|
The document is a technical report summarizing the investigation into the photolysis of FM3925, a fluorochemical, to determine its degradation and identify major products using various analytical methods.
|
1980 |
AR226-1030
|
vB0zJX76GR2VzkO45E0Vr418 |
22 |
|
The document reports on a pilot photolysis study conducted by 3M to investigate the degradation of the compound FM-3925 in aqueous solutions under natural sunlight conditions, indicating that isomerization is possible based on GC/MS analysis.
|
1980 |
AR226-1030
|
6w0B9QMEjk50mvLyGymdGLky1 |
9 |
|
The document details the synthesis and characterization of carbon-14 labeled N-Ethyl FOSE (2-N-ethylperfluorooctanesulfamido ethanol) conducted by 3M and Riker Laboratories, reporting a specific activity of 0.483 ± 0.020 µCi/mg and a purity of at least 98%, indicating its suitability for metabolism studies.
|
1980 |
AR226-0268
|
ZnmNLkxJX28xx3xvDNV3exBa8 |
20 |
|
This document reports on a toxicity test of perfluorooctanesulfonate (PFOS) conducted on freshwater rainbow trout, revealing a 96-hour EC50 value of 7.8 to 9.9 mg/L, indicating the concentration at which 50% of the fish would be expected to die.
|
1980 |
AR226-1030
|
B8GG8p8O24EM5OBrrnyN53OrL |
2 |
|
The document details a toxicity study on perfluorooctanesulfonate (PFOS) conducted on saltwater rainbow trout, assessing acute lethality over a 96-hour exposure period, but no mortality results were reported.
|
1980 |
AR226-1030
|
jMGG9O60Z6Da3dE1XOEk73rO |
2 |
|
The document reports on an activated sludge respiration inhibition test conducted on potassium decafluoro(pentafluoroethyl)cyclohexanesulfonate (FC-98) by 3M, indicating that there were no significant differences in oxygen uptake rates between the test substance at 100 mg/L and the blank control.
|
1980 |
AR226-1030
|
4v8Vq1834VYDMbyJxRKD2g50Q |
2 |
|
The document presents a compound-specific method for the quantitative characterization of organic fluorochemicals, including PFOA and PFOS, in biological matrices using negative ion electrospray tandem mass spectrometry, highlighting its application in analyzing human sera samples.
|
1980 |
AR226-0191
|
QX87Oo2xe4qkLGMaZjZnqaG36 |
22 |
|
The document reports on an oral teratology study of FC-95, a perfluorinated compound produced by 3M, which found that administration to pregnant rats resulted in teratogenic changes in the lens of the eye, particularly at a dose of 10 mg/kg/day, while lower doses did not show maternal toxicity or embryotoxic effects.
|
1980 |
AR226-0016
|
BRodwR71n6JyonO9d4jmjBQzk |
33 |
|
The document details the synthesis and characterization of carbon-14 labeled N-Ethyl FOSE (2-N-ethylperfluorooctanesulfamido ethanol) conducted by 3M and Riker Laboratories, confirming its specific activity and high purity for use in metabolism studies.
|
1980 |
AR226-0268
|
QknnBXORdw2G7OzmGpDRD6jRo |
20 |
|
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on eastern oyster larvae (Crassostrea virginica), noting that the test sample is FC-203 with 1.34% PFOS and various other components, and describes the methodology used for the toxicity assessment.
|
1980 |
AR226-0726
|
1gk2VBV6mrNEa550w0n8Y7Gma |
12 |
|
The document details an experiment assessing the foaming effects of a mixture containing perfluorooctanesulfonate (PFOS) as part of the FC-203A formulation, conducted using a modified OECD screening test, although the results may not accurately reflect the fluorochemical component due to impurities.
|
1980 |
AR226-0738
|
aDa0vQYxZZqx52MLDoXzD1KJY |
6 |
|
The document details an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the fish species Fundulus heteroditus, following a specific protocol, with results indicating the need for caution due to the presence of impurities in the test sample.
|
1980 |
AR226-0743
|
V3Jp0dDemDyO3xMDR7vBVRZ0w |
16 |
|
The document reports on a study evaluating the foaming effect of a mixture containing 0.67% PFOS and other components, indicating that the data does not accurately reflect the degradation potential of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1980 |
AR226-0779
|
eYroOO2wL3kevBD6qDyQ5m9m |
3 |
|
The document details a biodegradation test (OECD 301E) conducted on a mixture containing 0.67% PFOS, produced by 3M, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities.
|
1980 |
AR226-0778
|
Gm4NR6BQp9VRL2VvZR78Oq6Vx |
34 |
|
The document describes an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using juvenile mummichogs (Fundulus heteroclitus), noting that the test sample was primarily composed of water and various chemicals, but the LC50 values could not be calculated due to incomplete characterization of the mixture's impurities.
|
1980 |
AR226-0804
|
v2pX5BNdKBap1YjvRG6KVv7R |
14 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating potential toxicity levels based on the test conditions and methodology outlined.
|
1980 |
AR226-0837
|
4JR9a5e1z4NdD2xEw3pmvm6mN |
17 |
|
The document reports on a biodegradation test (OECD 301D) for a mixture containing 0.58% PFOS, conducted by 3M, indicating that the data does not accurately reflect the degradation potential of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1980 |
AR226-0871
|
V359YKRKayyg2ZpnLbk1JoB3q |
11 |
|
The document discusses a comparison of two N-EtFOSE alcohols, FM-3422 and FM-3924, used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0277
|
MJqBL6M1yk23E3o6vgx8RJXmj |
1 |
|
The document reports on an oral teratology study of FM-3422, revealing that it caused teratogenic effects such as developmental eye abnormalities, cleft palates, and skeletal malformations in rat fetuses when administered to pregnant Sprague-Dawley rats during organogenesis, while also noting maternal toxicity at higher doses.
|
1980 |
AR226-0280
|
0gn2YxMMxgk8XpV8p87R98NnM |
26 |
|
The document compares two formulations of N-EtFOSE Alcohol (FM-3422 and FM-3924) used in teratology studies, detailing their composition and production methods.
|
1980 |
AR226-0281
|
zokG9mBdy5eb88ozEEQqyamqm |
1 |
|
The document compares two formulations of N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies, detailing their chemical compositions and production methods.
|
1980 |
AR226-0284
|
4nbbbaJrr49Qg2BZyw1Zmj |
1 |
|
This document reports on a biodegradation test conducted by 3M Company on a mixture containing perfluorooctanesulfonate (PFOS) and other components, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking reliable conclusions due to insufficient characterization of the test substance and methodology.
|
1980 |
AR226-0924
|
YDDVYR8Yj4pQgQgw7ZQgeojvK |
12 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating that the test sample was a 1.356% solution of L-4647 with 6.6% PFOS and various other components, although the method and specific toxicity results are not provided
|
1980 |
AR226-0925
|
Z6vb9yjDOqNNy9qxR7QQRwjY |
6 |
|
The document reports on an acute toxicity test of Perfluorodecanesulfonate (PFDS) on the aquatic invertebrate Daphnia magna, conducted by 3M in 1988, using a mixture containing approximately 22-26% PFDS, with results indicating the test conditions and monitoring parameters.
|
1980 |
AR226-0389
|
09K16r8QBvO2MyQY660g6X0b |
18 |
|
The document reports on a study conducted by Riker Laboratories, a subsidiary of 3M, which found that after a single oral dose of the perfluorinated compound FC-143 (mean dose of 11.0 mg/kg) to male rats, at least 93% of the total carbon-14 was absorbed within 24 hours, with a plasma elimination half-life of 4.
|
1980 |
AR226-0455
|
31pZanDV235KOo0r6VX1owpO |
15 |
|
The document is an update on a retrospective cohort mortality study conducted by University of Minnesota epidemiologists on employees at the 3M Chemolite Plant, which found no statistically significant differences in mortality rates, including prostate cancer deaths, among workers exposed to perfluorinated compounds.
|
1980 |
AR226-0471
|
0eRQOYagR2z95Beop9GonR2J |
28 |
|
The document details a biodegradation study of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt) conducted by 3M Company, indicating unreliable results due to insufficient characterization of the test substance and method, with no reliable conclusions drawn from the study.
|
1980 |
AR226-0492
|
Lb68mepYZxdpjGw6Rn99ryrz |
9 |
|
The document reports on a study conducted by 3M Company evaluating the acute toxicity of ammonium perfluorooctanoate (PFOA ammonium salt) on activated sludge respiration, finding no acute inhibitory effect at a concentration of 1000 mg/L after 7 minutes of contact time.
|
1980 |
AR226-0505
|
5LBZ9RRXxwQ4QLdZxLNbN5nb8 |
4 |
|
The document reports on an acute toxicity test of Perfluorodecanesulfonate (PFDS) on the aquatic invertebrate Daphnia magna, conducted by 3M, indicating the test was completed in 1988 under GLP conditions, with specific details on test conditions and methodology.
|
1980 |
AR226-0389
|
KGGwaL7KqQ8Ba65xg1en23qXN |
18 |
|
This document reports on a study conducted by Riker Laboratories, Inc., a subsidiary of 3M, which found that after a single oral dose of the perfluorinated compound FC-143 (mean dose of 11.0 mg/kg) in male rats, at least 93% of the total carbon-14 was absorbed within 24 hours, with a plasma elimination half-life of
|
1980 |
AR226-0455
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B5ZE00kdYprq2bNq10yvnwm8E |
15 |
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The document is an update on a retrospective cohort mortality study conducted by University of Minnesota epidemiologists on employees at the 3M Chemolite Plant, which found no statistically significant differences in mortality rates, including prostate cancer deaths, compared to expected rates in the general population.
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1980 |
AR226-0471
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jZZZ37jvbwgdYzn1qd4Y0REO |
28 |
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The document details a biodegradation study of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt) conducted by 3M Company, indicating unreliable results due to insufficient characterization of the test substance and inconsistent data.
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1980 |
AR226-0492
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5oYgmY6oZXJme3E4KKvX8QR8 |
9 |
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The document reports on a study conducted by 3M Company evaluating the acute toxicity of ammonium perfluorooctanoate (PFOA ammonium salt) on activated sludge respiration, concluding that it does not inhibit respiration at a concentration of 1000 mg/L with a limited contact time of 7 minutes.
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1980 |
AR226-0505
|
9JxvqEmqGqVVQ5xbRrobv76mL |
4 |
|
Unreadable document.
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1980 |
AR226-1980
|
jgpj9VrN1MYGL900M7G8ynn1Z |
13 |
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The document is an analytical report from E.I. du Pont de Nemours and Company detailing the Fluorine-19 NMR analysis of perfluoro-n-octanoic acid and other related fluorocarbon materials, indicating high purity levels of the samples tested.
|
1980 |
AR226-2378
|
5kyBbxg4mBzeGe0yQjy2xNebz |
2 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Company evaluating the airborne concentration of ammonium perfluorooctanoate (PFOS) using a dust generator, which found no detectable vapor downstream after 40 hours of exposure.
|
1980 |
AR226-2754
|
gDY1mV65MQ3QLwN5aEgy2bDLJ |
2 |
|
This document from Haskell Laboratory provides information on Ammonium Perfluorooctanoate (C-8), detailing its physical properties, toxicity levels, and findings from clinical studies on occupationally exposed workers, indicating that PFOA has a long half-life in humans with blood levels showing only a 45% reduction over 18 months after removal from exposure.
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1980 |
AR226-3376
|
gbe06gmypjL2xGdr2Dp49Zg3J |
6 |
|
The document details an experiment assessing the foaming effects of a mixture containing perfluorooctanesulfonate (PFOS) in the context of a Modified OECD Screening Test, indicating that the data may not accurately reflect the effects of the fluorochemical component due to incomplete characterization of impurities.
|
1980 |
AR226-0738
|
6bqdzOEpkXyqy1p2qJEmy9nBg |
6 |
|
The document describes an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the fish species Fundulus heteroditus, following a specific protocol, with results indicating the test sample's toxicity may not accurately reflect that of the pure fluorochemical component due to impurities.
|
1980 |
AR226-0743
|
qkzeJe2bLJQnpb3vgEJnm1aX5 |
16 |
|
The document details an acute toxicity test conducted on a mixture containing 0.73% perfluorooctanesulfonate (PFOS) using juvenile Fundulus heteroclitus fish, following the EG & G Bionom ics protocol, but notes that LC50 values could not be calculated due to incomplete characterization of the sample's impurities.
|
1980 |
AR226-0804
|
YjEZeQYmrv1r2Xbb0mgQvp9MV |
14 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% perfluorooctanesulfonate (PFOS) produced by 3M, indicating the test's methodology and conditions, although it notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1980 |
AR226-0837
|
44qVqVad8vyqp2XxXqmpdjboV |
17 |
|
The document details a biodegradation study (OECD 301D) of a mixture containing 0.58% PFOS, conducted by 3M, indicating that the data does not accurately reflect the degradation potential of the fluorochemical component due to incomplete characterization of impurities.
|
1980 |
AR226-0871
|
305KoYXOJpK6BdzQ0M01yY5J |
11 |
|
The document reports on a biodegradation test conducted by 3M Company on a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks reliable conclusions due to insufficient characterization of the test substance and methodology.
|
1980 |
AR226-0924
|
g2r6vwgp7J2kExLJwedRx5ZbJ |
12 |
|
The document details an acute toxicity test on fish (fathead minnow) using a mixture containing 6.6% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating that the test was conducted to determine the LC50 values over a 96-hour exposure period.
|
1980 |
AR226-0925
|
G5Kpx1Z1MmNoEdeKRv3dNXrDV |
6 |
|
The document compares two formulations of N-EtFOSE alcohol (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, detailing their chemical compositions and production methods.
|
1980 |
AR226-0612
|
qmdRdQ4qbeJmzkJg8qaRxmpbK |
1 |
|
The document compares two formulations of N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0612
|
XyyxL638GB7VrvbJMk5z0ajy |
1 |
|
The document discusses a comparison of two N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies at Riker Laboratories, highlighting their production methods and chemical compositions.
|
1980 |
AR226-0612
|
XOgoRZBwdbwD6gJJ3wjZ0E0N4 |
1 |