|
The document reports on an activated sludge respiration inhibition test for a mixture containing 4% PFOS, conducted by 3M, which found no inhibition of activated sludge respiration at a concentration of 1000 mg/L.
|
1982 |
AR226-0687
|
OzLQBM4ZzwodKgy5MgRd8m1we |
4 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically a mixture containing 1.34% PFOS, and reports various toxicity levels including EC50 values for Photobacterium phosphoreum, Scenedesmus subspicatus, Daphnia magna, and Brachydanio rerio.
|
1982 |
AR226-0733
|
La1wpN5ZBx6QV87JZEOBkwY3 |
26 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically noting that the test sample FC-206 contains 0.67% PFOS and provides various toxicity results including EC50 values for Photobacterium phosphoreum, freshwater algae, and Daphnia magna.
|
1982 |
AR226-0792
|
Z8JadgGRMJrg8wDNxqenxm4Ep |
26 |
|
The document reports on an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% PFOS, indicating no mortality during the 96-hour exposure period.
|
1982 |
AR226-0838
|
ppdxjvEGZgbEagwZLRyvLb2XB |
12 |
|
The document summarizes biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) from 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient methodological details.
|
1982 |
AR226-0868
|
65b23RQkqD1jyB9V2Nqr2K8Z3 |
9 |
|
The document is an analytical report confirming that FM-3924, a perfluorinated compound, meets quality control specifications and is stable, based on various chemical analyses conducted for Riker's teratology study.
|
1982 |
AR226-0279
|
0gw393yZY0ZoxJR2bmR22g9bV |
2 |
|
The document is an internal analytical report evaluating the chemical FM-3924, which was analyzed for a Riker teratology study, confirming its structure and providing detailed gas chromatography and elemental analysis results.
|
1982 |
AR226-0286
|
4JvZJN8Q3j9V2DQmmrobwJ1bj |
2 |
|
The document reports on a biodegradation test of Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted by 3M Company, indicating that while some biodegradation occurred in aerobic conditions, the specific contribution of the test substance to the observed chemical and biochemical oxygen demand values remains unclear due to the mixture's composition and lack of detailed methodology.
|
1982 |
AR226-0392
|
JJL1bGXGL5MZ4JJNwv6JqEV1e |
7 |
|
The document is a letter from Dr. E. Marshall Jo to Dr. Franklin D. Griffith stating that FC143, a substance tested for developmental toxicity in pregnant rats and rabbits, poses no hazard to the conceptus, and therefore no further testing is necessary.
|
1982 |
AR226-0467
|
mb94OQ9L15qjRm982XZJgv7dk |
1 |
|
The document is an internal correspondence summarizing health evaluations conducted in 1981 for 264 employees at Chemolite, with a focus on comparing testing data with blood fluorine levels as part of the fluorochemical program.
|
1982 |
AR226-0480
|
rB397Rq1Badxg2o6jZr4oJZZr |
1 |
|
The document details a chronic toxicity study of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) on freshwater invertebrates (Daphnia magna), conducted by 3M, indicating that the test substance was a mixture with a purity of 96.5 - 100% and outlining the methodology and conditions of the study.
|
1982 |
AR226-0508
|
dQ78GXjN7j34041EjbBJQxMrq |
25 |
|
The document is a letter from Dr. Franklin D. Griffith expressing gratitude for the cooperation received during a visit to 3M, where he reviewed raw data and specimens related to a study on fetal rat eyes, ultimately concluding that many previously reported abnormalities were actually normal findings, indicating issues with the original study's methodology.
|
1982 |
AR226-0530
|
wrxMyZjn5ZO9m2gKXg6ZGj64Q |
2 |
|
The document reports on a biodegradation test of a mixture containing Perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) conducted by 3M Company, indicating that some portion of the test sample biodegraded in aerobic environments, although the specific contributions of the test substance to the observed biodegradation values remain unclear.
|
1982 |
AR226-0392
|
LzX8neYpNL8GXZE4Nz5DQEJb |
7 |
|
The document reports on blood C-8 (PFOA) levels among employees at E. I. du Pont de Nemours & Company, indicating higher accumulation rates in Fine Powder Zone 4 Operators compared to FEP Zone 4 Operators, with a general downward trend observed in long-term employees, although further data is needed for statistical significance.
|
1982 |
AR226-1612
|
n9oL6kex21VJ4jXx54Ewjjrpm |
5 |
|
The document discusses recommendations for periodic blood tests for employees potentially exposed to FC-143, indicating that "Teflon" operators have low blood levels and exposure, and suggests these tests be included in their routine physical examinations.
|
1982 |
AR226-1613
|
pBn9NwgXJqLY8wLo0GOpnxaXa |
1 |
|
This document reports on the detection of organic fluoride levels in the blood of Experimental Station employees, linked to by-products from HFPO synthesis, and outlines a program to investigate health impacts and improve monitoring related to this exposure.
|
1982 |
AR226-1615
|
xG3VrjEpN7Mm8m6j71LNxq7b |
1 |
|
The document outlines a plan by DuPont and 3M to reduce blood sampling for C-8 (perfluorooctanoic acid, PFOA) among employees, focusing on those with direct exposure, while continuing to monitor certain individuals to assess the elimination rate of C-8 from the blood.
|
1982 |
AR226-1616
|
BRRD3jRy0ZRVBvQbKmEOVE31E |
1 |
|
The document outlines a procedure for analyzing blood serum for FC-143, a perfluorinated compound, detailing the extraction and conversion methods used to prepare samples for gas chromatography analysis.
|
1982 |
AR226-1614
|
nkNNRkN1a8gZjr7GG0z66mBwR |
3 |
|
The document reports on trends in blood C-8 (PFOA) levels among TEFLON employees, indicating a significant average decrease of 23% for FEP Operators and 18% for Fine Powder and Granular Operators from October 1981 to June 1982, while new employees are accumulating C-8 at a lower rate than in previous years.
|
1982 |
AR226-1617
|
by75VenR65YdnBbL1Odda3kL0 |
9 |
|
The document discusses the retention of ammonium perfluorooctanoate (C-8) in the blood of TEFLON employees, estimating that approximately 40% of inhaled C-8 vapor is retained, with variations based on individual absorption rates and airborne particle sizes.
|
1982 |
AR226-1619
|
evaRnge6eL5xk5oeJMG0Bp7Zy |
3 |
|
The document discusses the decision not to pursue a program for monitoring C-8 (PFOA) blood levels in TEFLON employees due to recent findings on its embryotoxicity and declining blood levels, while supporting additional blood sampling for certain employees and emphasizing the need for a detailed epidemiological study to determine safe blood levels.
|
1982 |
AR226-1620
|
9o98xBaLgLgpyvJ6yYzYgqeq |
1 |
|
The document discusses a request to increase the frequency of blood sampling for C-8 (PFOA) data among retired male employees and those transferred from the Fluoropolymers Division to improve the understanding of C-8 elimination rates from the body.
|
1982 |
AR226-1621
|
QJ8L8ZYKZoK0qknpxm3zpg5o5 |
1 |
|
The document discusses the retention of ammonium perfluorooctanoate (C-8) in human blood among Teflon workers, suggesting modifications to the interpretation of blood concentration data to better understand human exposure and its correlation with animal models.
|
1982 |
AR226-1622
|
aJR46RLp9Lbw8vxbprw5nGbVN |
3 |
|
This document discusses the inadequacy of current data on C-8 (PFOA) blood levels and elimination rates among employees at the Teflon Polymer Division, emphasizing the need for accurate monitoring of personnel no longer exposed to C-8 to assess long-term health implications.
|
1982 |
AR226-1624
|
eg6GOzMD1mqYEw6EjbgVbDmy |
1 |
|
This document discusses the retention of ammonium perfluorooctanoate (C-8) in the blood of Teflon employees, with estimates indicating that less than 100% of inhaled C-8 vapor is retained in the body, and it takes approximately 420 days for the body to eliminate half of the accumulated C-8.
|
1982 |
AR226-1623
|
zoNpGpZ3r2M1Jjgv5k7b18Yya |
8 |
|
This document reports the analysis of 14 blood samples for perfluorooctanoate (PFOA) by gas chromatography, indicating that most samples had very low concentrations, with some indistinguishable from the blank and others below the quantitation limit.
|
1982 |
AR226-1625
|
N2gvnRvo55G2kKKKjoa9MjK5R |
2 |
|
The document is a letter from Dr. E. Marshall Jo to Dr. Franklin D. Griffith stating that FC143, a perfluorinated compound, has been adequately tested for developmental toxicity in pregnant rats and rabbits, concluding that it poses no hazard to the conceptus and recommending no further testing.
|
1982 |
AR226-0467
|
ykNazy317B2j5znBzddv20xrd |
1 |
|
The document discusses health evaluations conducted in 1981 for 264 employees at Chemolite, focusing on the assessment of health impacts related to fluorochemical exposure, with plans to compare testing data with blood fluorine levels and review health testing schedules.
|
1982 |
AR226-0480
|
kZL1EmyXRwXxLZg6YyMbpV5V |
1 |
|
The document details a chronic toxicity study of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted by 3M on Daphnia magna, indicating that the test substance was a mixture with a purity of 96.5 - 100% and outlining the methodology and conditions of the study.
|
1982 |
AR226-0508
|
LGdo9XyKKnkkdYBMwbrpqLpb |
25 |
|
The document discusses a review of anatomical specimens related to a study on the effects of a test substance, indicating that previously reported abnormalities in fetal rat eyes were misidentified and that the evaluation process lacked proper coding and documentation.
|
1982 |
AR226-0530
|
XO4KkKXDaJmqqyRdL3DBre3EJ |
2 |
|
The document outlines an updated program to reduce employee exposure to C-8 (perfluorooctanoic acid, PFOA) at a facility, highlighting that air sampling during a cleanup showed 31 out of 32 samples were below the minimum detectable level, indicating that residual dust is not a significant airborne source, although it remains a concern for skin contact.
|
1982 |
AR226-1982
|
Kmb6BJD5oDXk4QBRZvx9zb30 |
3 |
|
The document reports on a study conducted by E.I. Du Pont de Nemours and Company, titled "H-24215: Static, Acute, 96-Hour LC50 to Rainbow Trout, Oncorhynchus mykiss," which assesses the acute toxicity of a perfluorinated compound to rainbow trout in compliance with EPA and OECD guidelines.
|
1982 |
AR226-2801
|
pmqd0NmNGyDYbKjaJB6k3aKn6 |
31 |
|
The document reports the results of an acute oral toxicity study (LD50) conducted by E.I. du Pont de Nemours Company on male Sprague-Dawley rats, determining an LD50 value of 2,150 mg/kg for the tested substance.
|
1982 |
AR226-2907
|
jqJ8QV2yQZNpwNXbXda0N5qN |
4 |
|
The document reports on an industrial hygiene survey conducted by DuPont to evaluate air concentrations of perfluorinated compounds during the operation of a spinning machine in Camden, South Carolina, finding personnel exposure levels below the acceptable limits and recommending resampling to confirm safety.
|
1982 |
AR226-2908
|
QMgy9nB1xajG95Jg305Eo7dLv |
5 |
|
The document is a summary of a trial hygiene survey conducted by DuPont's Textile Fibers Department in Seaford, which measured air exposure levels of perfluorinated compounds among spinning machine operators, indicating that exposure levels were below the 5 mg/m³ threshold.
|
1982 |
AR226-2909
|
Rj9bMEzbV3MXGX6J4XY4NG2mV |
9 |
|
This document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M in 1982, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking reliable data quality and method characterization.
|
1982 |
AR226-0685
|
ypnp98kerYyDddkV2davLzNyE |
3 |
|
The document details an acute toxicity test conducted on juvenile Pimephales promelas (fathead minnows) using a mixture containing 4% perfluorooctanesulfonate (PFOS) from a 3M production lot, with the study completed in 1982 under static conditions for a 96-hour exposure period.
|
1982 |
AR226-0686
|
xjkNjaRZ7mDnMw4D5GYE3gka6 |
12 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 4% PFOS, conducted using a sample from 3M, which showed no inhibition of activated sludge respiration at a concentration of 1000 mg/L.
|
1982 |
AR226-0687
|
65KL5mj9O1YQ5okjQbqk8n7q4 |
4 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically highlighting the composition and toxicity results of a mixture containing 1.34% PFOS, with key findings including EC50 values for various aquatic organisms.
|
1982 |
AR226-0733
|
byw62LQvVJ8pEVpd7L1g258yD |
26 |
|
The document summarizes a study conducted by the German Army on the environmental properties of foam extinguishing agents, specifically focusing on a mixture containing 0.67% PFOS (perfluorooctanesulfonate) from 3M's FC-206, with various toxicity results reported for aquatic organisms.
|
1982 |
AR226-0792
|
x6Yaqpd2XwB2bJYbg8egBZRg |
26 |
|
The document reports on an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% PFOS from a 3M product (FC-600), indicating no mortality during the 96-hour exposure period.
|
1982 |
AR226-0838
|
MoaEG732R1ObMxrb3NQOnxj69 |
12 |
|
The document presents biodegradation study results for a mixture containing perfluorooctanesulfonate (PFOS) from 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient methodological details.
|
1982 |
AR226-0868
|
zoKG6DaQGO3LD9mwdx2byEDR7 |
9 |
|
This document outlines the findings of organic fluoride levels in the blood of Experimental Station employees, linked to by-products of HFPO synthesis, and details a program to investigate health impacts and implement further testing and communication with affected employees.
|
1982 |
AR226-1615
|
Yj2dyqQye0aQR09Bg50XNm8Zy |
1 |
|
The document discusses the recommendation for periodic blood tests for employees potentially exposed to FC-143 (a perfluorinated compound) to monitor their blood concentration levels, noting that "Teflon" operators have shown relatively low exposure levels.
|
1982 |
AR226-1613
|
b5E1zpEQp4xkwwv6E6VQbkdv6 |
1 |
|
The document discusses the decision not to pursue a program for achieving a C-8 material balance for TEFLON employees due to recent findings on C-8 embryotoxicity and declining blood levels, while supporting additional blood sampling for certain employees and emphasizing the need for a detailed epidemiological study to determine safe blood levels of C-8.
|
1982 |
AR226-1620
|
1Q0q3EGrVKwKnB3n6pmY0LGYX |
1 |
|
The document outlines a plan to reduce the blood sampling program for C-8 (perfluorooctanoic acid, PFOA) at DuPont and 3M, stating that no adverse health effects have been detected at current levels, while continuing to monitor specific personnel with potential exposure.
|
1982 |
AR226-1616
|
6M8dK4bQ0vRXm8ragDBy3Mmg |
1 |
|
The document discusses a request for increased blood sampling frequency for retired male employees and those transferred from the Fluoropolymers Division to gather more data on C-8 (PFOA) elimination rates, due to previously low participation in the program.
|
1982 |
AR226-1621
|
mkmbe8NXDxJ0ad4doNvOovQk |
1 |
|
The document discusses the inadequacy of current data on C-8 (PFOA) blood levels and elimination rates among employees at the Teflon Polymer Division, emphasizing the need for accurate monitoring of individuals no longer exposed to C-8 to assess long-term health implications.
|
1982 |
AR226-1624
|
yqJnj7wLwDYM67Bypzpnqja2 |
1 |
|
The document is a letter from Dr. E. Marshall John to Dr. Franklin D. Griffith stating that FC143, a substance tested in developmental toxicology studies on pregnant rats and rabbits, poses no hazard to the conceptus and does not require further testing.
|
1982 |
AR226-0979
|
jygwKE8njNaEMaaLe04axKXGR |
1 |
|
The document outlines health evaluations conducted in 1981 for 264 employees at Chemolite, including comparisons of testing data with blood fluorine levels as part of the fluorochemical program, with results to be reported later.
|
1982 |
AR226-0979
|
qqdx7wEQeO7LnvVBvoxRGqkx |
1 |
|
This document is a two-year oral toxicity and carcinogenicity study of the fluorochemical FM-3924 conducted by RIKER Laboratories, Inc. for 3M Company, detailing the methodology, results, and conclusions regarding its effects on rats.
|
1981 |
AR226-0257
|
Qj1YqX0LYQEN478rDXVRDB4R |
361 |
|
This document details an oral rangefinder study conducted by Riker Laboratories, Inc. on the substance T-2999CoC, sponsored by 3M Commercial Chemical Division, to determine the upper dose level for a subsequent teratology study in pregnant rabbits.
|
1981 |
AR226-0275
|
xdL8xX7ngN6pa4xv0KZEKNjgb |
10 |
|
The document reports on a two-year oral toxicity and carcinogenicity study of fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, detailing macroscopic and microscopic observations of lesions and tissue changes in rats exposed to the substance.
|
1981 |
AR226-0258
|
RpyEYpKV4aoX2qM7x5p768oMk |
330 |
|
The document reports on an oral teratology study of T-2999CoC, sponsored by 3M, which found that while the compound was not teratogenic in pregnant rabbits, it exhibited embryotoxic effects at a high dose of 15 mg/kg/day, leading to increased abortions and poor neonatal survival.
|
1981 |
AR226-0276
|
6Ra1pyD9aqneNX0vaRryojndg |
37 |
|
The document reports on the analytical results of four corn oil samples containing varying concentrations of FM-3924, indicating that while the samples showed good reproducibility, the solubility of FM-3924 was low and crystallization could pose issues for a rat feeding study.
|
1981 |
AR226-0278
|
zXk1D3Gme2vybMjMj93r2dz7 |
1 |
|
The document details a two-year oral toxicity and carcinogenicity study of fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, focusing on the effects of this compound on female rats.
|
1981 |
AR226-0261
|
v19DVe9EewM7mNkDxgVkkGdGm |
275 |
|
The document reports on a teratology study evaluating the effects of T-2999CoC on rat lenses during organogenesis, concluding that lens abnormalities observed were artifacts rather than compound-related effects, with no significant differences in histological appearance across dose groups.
|
1981 |
AR226-0282
|
0qYwRnKnk2vybOg15RxyjJMoJ |
21 |
|
This is a report on a Special Lens Oral Teratology Study of T-2999CoC conducted by Riker Laboratories, detailing the effects of the compound on fetal rat lenses across two strains of rats during gestation.
|
1981 |
AR226-0283
|
3NGDEoyvb05ZgX5baVE56B81O |
48 |
|
The document reports on the analytical results of four corn oil samples containing varying concentrations of FM-3924, indicating that while the samples showed good reproducibility, the solubility of FM-3924 was low and crystallization could pose issues for a rat feeding study.
|
1981 |
AR226-0285
|
6RvnYGLwezL1D2pDYZdz88Gwd |
1 |
|
The memo from K. G. Lamprecht discusses the misinterpretation of a fetal rat lens artifact as a teratogenic effect in Riker Experiments Nos. 0680TR0008 and 0680TR0010, detailing the nature of the lens abnormalities and the factors leading to the incorrect conclusion.
|
1981 |
AR226-0287
|
3Qa6xgkXLB6O9kDJ0eegzgz03 |
3 |
|
This document details a two-year oral toxicity and carcinogenicity study of the fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, focusing on its effects in rats.
|
1981 |
AR226-0259
|
OzN0vLZ1rY12gZ8DwaVBObGXp |
339 |
|
The document details a two-year oral toxicity and carcinogenicity study of fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M, focusing on its effects in male rats from April 1981 to May 1983.
|
1981 |
AR226-0260
|
KzK5ZEm5oG0dRmqvgDGxJmZY2 |
325 |
|
The document reports on a Fluorochemical Control Study analyzing medical surveillance data from 1981 of Decatur chemical and film plant workers, finding no statistically significant correlations between various health markers and total organic fluorine levels, with a reference to perfluorooctanesulfonate as a component of total organic fluorine in the sera of some employees.
|
1981 |
AR226-0035
|
NEXaRQyNjRawgvRXVvBdvL9dQ |
9 |
|
The document reports on the solubility characteristics of CS-2070, a compound related to CS-2151, indicating that CS-2070 is soluble in water and various organic solvents, with specific solubility levels determined at different pH levels.
|
1981 |
AR226-1030
|
zzwv2401q1NzL9Xb3wmqz8GD7 |
1 |
|
The document is an analytical report detailing the partition coefficient determination of the perfluorinated compound CS-2151 and its solid form CS-2070, which were characterized for their distribution between n-octanol and water.
|
1981 |
AR226-1030
|
X45ReB3y1KNQooyzYXjoRykG |
2 |
|
The document is an analytical report detailing the thermal analysis and melting point determination of a substance labeled CS-2070, derived from CS-2151, which was characterized for PMN purposes and showed a melting point range of 75°C to 145°C.
|
1981 |
AR226-1030
|
ejZ05jYYbjeMRvwepVpdZOKg |
2 |
|
This document reports on a toxicity study conducted by 3M Company in 1984, assessing the effects of perfluorooctanesulfonate (PFOS) on aquatic invertebrates, specifically Daphnia magna, with key findings indicating various EC50 values for immobilization and reproduction, although the study's reliability is noted to be limited due to unmeasured actual concentrations and un
|
1981 |
AR226-0110
|
zQ1VQEOMvDwoJyGmBNk16nVqm |
14 |
|
The memo discusses the misinterpretation of a fetal rat lens artifact as a teratogenic effect in Riker Experiments Nos. 0680TR0008 and 0680TR0010, detailing the morphological changes observed and clarifying that these changes were not indicative of teratogenicity.
|
1981 |
AR226-0329
|
jgKxdJz9YgZeD8Op2w34oeK99 |
3 |
|
The document reports on an acute ocular irritation test of the substance T-2997CoC conducted on female albino rabbits at Riker Laboratories, revealing that it caused severe irritation and various ocular effects after brief contact.
|
1981 |
AR226-0979
|
7MzZDQzKDMGBd5JJKQkEgoqZe |
17 |
|
The document is a final report from SRI International assessing the mutagenic activity of 3M Company's Compound T-2997CoC using the Ames Salmonella/microsome assay and Saccharomyces cerevisiae D3, concluding that the compound was not mutagenic or recombinogenic in any of the assays performed.
|
1981 |
AR226-0979
|
MMnY8Ly638a0KVNxpxN6pGvj9 |
17 |
|
The document reports on an acute oral toxicity study of the substance T-30670OC conducted on albino rats, indicating that the approximate oral LD50 is greater than 5,000 mg/kg, with no observed mortalities or adverse effects during the observation period.
|
1981 |
AR226-0979
|
DvdyRdz7OOjoMbzY04D6wnzmo |
8 |
|
The document presents fluorine measurement data for employees exposed to PFOS at a facility in Decatur, analyzing historical data from 1981 to 1997 and detailing the mean fluorine levels for groups of employees based on the number of measurements taken.
|
1981 |
AR226-0176
|
per89g0O3Ek5g6wpdw3aM8z47 |
12 |
|
The document reports on an acute oral toxicity study of T-3066CoC conducted on albino rats at Riker Laboratories, Inc., revealing an approximate LD50 of less than 5,000 mg/kg and greater than 500 mg/kg, with significant behavioral reactions observed at the higher dosage.
|
1981 |
AR226-0238
|
KJLNQo1rrLaOreq2gwKwznbVr |
10 |
|
The document reports on an acute toxicity test conducted on Daphnia magna using a mixture of decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2151) produced by 3M, detailing the test conditions and methodology but not providing specific toxicity results.
|
1981 |
AR226-1030
|
Mod3myakpZMv0DdbdDBe73Bgy |
2 |
|
The document reports on biodegradation testing of CS-2151 (a mixture of decafluoro(pentafluoroethyl)cyclohexanesulfonate DEA salt) conducted by 3M, indicating that the 20-Day Biochemical Oxygen Demand (BOD) was equivalent to 90% of the theoretical oxygen demand for the diethanolamine portion of the molecule, although
|
1981 |
AR226-1030
|
4vvZzZQzdmzjzVKya4o1j8yOp |
2 |
|
The document reports on a biosorption study of decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2070) conducted by 3M, indicating that while heat-killed activated sludge adsorbs the substance, viable sludge does not, suggesting CS-2070 remains in aqueous solution during wastewater treatment.
|
1981 |
AR226-1030
|
k6MaGYmaBKL9yZz2vyjBDpXpE |
2 |
|
The document is an analytical report detailing the thermal analysis and melting point determination of a light yellow solid labeled CS-2070, derived from a liquid labeled CS-2151, with findings indicating a melting point range of 75°C to 145°C and stability to 200°C.
|
1981 |
AR226-1030
|
a4D3yxnDGV5NdBoDpprYzR8bY |
2 |
|
The document reports the melting point of Decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2070) as observed at 75°C for the initial melt and 145°C for complete melting, based on a study conducted by 3M Company in 1981.
|
1981 |
AR226-1030
|
wrDpqpwK40dMQ881MRZYVKga3 |
2 |
|
The document is an analytical report detailing the partition coefficient determination of the perfluorinated compound CS-2070, derived from CS-2151, using a method involving n-octanol and water to assess its solubility and distribution.
|
1981 |
AR226-1030
|
LpYra3jZeEJkmdGj56Z3rwEZw |
2 |
|
The document reports that a microbial respiration inhibition test conducted on the perfluoro(ethylcyclohexyl) sulfonate (CS-2151) showed no acute inhibitory effect on the respiration rate of microorganisms at a concentration of 1000 mg/L.
|
1981 |
AR226-1030
|
OzLOkpX2DpgXrVJpGy9bGRdVQ |
2 |
|
The document reports on a solubility study of Decafluoro(pentafluoroethyl)cyclohexanesulfonate (CS-2070) conducted by 3M in 1981, indicating that its solubility in neutral, buffered water is greater than 25%.
|
1981 |
AR226-1030
|
K6v4JXwdaDDdJQvz6p6rm2Nx0 |
2 |
|
The document reports on the solubility characteristics of CS-2070, a compound derived from CS-2151, indicating that it is soluble in various solvents and buffers, with specific solubility levels noted at different pH values.
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1981 |
AR226-1030
|
9x0a1m0BDJR6kanyxvd5nej6 |
1 |
|
The document reports on an acute oral toxicity study of T-3065CoC conducted on albino rats, revealing an LD50 greater than 5,000 mg/kg and noting adverse effects such as diarrhea and lethargy, along with gastrointestinal hemorrhage in deceased animals.
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1981 |
AR226-0246
|
evEnygYGeLVQn6D8g9YB4KLaG |
9 |
|
This document reports on a toxicity study of perfluorooctanesulfonate (PFOS) conducted on Artemia sp., finding an acute 48-hour EC50 value of approximately 9.4 mg/L, indicating the concentration at which 50% of the organisms experienced mortality.
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1981 |
AR226-1030
|
zQjz4NLamMv2xdq6GE7E6qG70 |
2 |
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The document reports on an acute oral toxicity study of T-3066CoC conducted on albino rats, indicating an approximate LD50 of less than 5,000 mg/kg and greater than 500 mg/kg, with behavioral reactions observed at the higher dosage.
|
1981 |
AR226-0238
|
2Je0B1jZ4O2ExjNBGq9d7dvM5 |
10 |
|
The document reports on an acute oral toxicity study of T-3065CoC conducted on albino rats, finding an LD50 greater than 5,000 mg/kg with observed symptoms including diarrhea and lethargy, and noting gastrointestinal hemorrhage in deceased animals.
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1981 |
AR226-0246
|
aDD3MGeK1Oa7dKxJp2jBVzE9Y |
9 |
|
The document details a two-year oral toxicity and carcinogenicity study of the fluorochemical FM-3924 conducted by RIKER Laboratories, Inc. for 3M Company, focusing on its effects in rats.
|
1981 |
AR226-0257
|
pqgpeDV3Dmkv1XJJ8pDZB33d |
361 |
|
This report analyzes medical surveillance data from 1981 of Decatur chemical and film plant workers, finding no significant correlations between various health markers and total organic fluorine levels, while noting that perfluorooctanesulfonate was previously identified as a component of total organic fluorine in the sera of some employees.
|
1981 |
AR226-0035
|
8xV9eG9EMye0MQvKvZrJQY5d |
9 |
|
This document details a two-year oral toxicity and carcinogenicity study of fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, reporting various macroscopic and microscopic observations in rats, including lesions and chronic conditions in multiple organs.
|
1981 |
AR226-0258
|
JrbD7x5ZvakopoXe7BZBQ653r |
330 |
|
The document details a two-year oral toxicity and carcinogenicity study of fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, focusing on the effects of this compound in female rats.
|
1981 |
AR226-0261
|
GaMQ79bDGYJRzEqM372GR05Y |
275 |
|
The document details a two-year oral toxicity and carcinogenicity study of the fluorochemical FM-3924 conducted by Riker Laboratories, Inc. for 3M Company, focusing on its effects in rats.
|
1981 |
AR226-0259
|
vB9YLjed4EyjmOJ5LrB72ZRmb |
339 |
|
This document reports on a toxicity study conducted by 3M Company in 1984, evaluating the effects of perfluorooctanesulfonate (PFOS) on aquatic invertebrates (Daphnia magna), with key findings indicating various EC50 values for immobilization and reproduction, although the study's reliability is limited due to unmeasured actual concentrations and uncharacterized sample purity
|
1981 |
AR226-0110
|
19DYeM95NjrpX3dMvbrzmR4d |
14 |
|
This document details a biodegradation test (OECD 301E) conducted on a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the test sample was prepared with a specific concentration of PFOS and analyzed for its ready biodegradability using a mix of soil extract and wastewater effluent.
|
1981 |
AR226-0711
|
Ev1qwVewMQ7ZD0kd9jJdomv4N |
20 |
|
The document summarizes multiple biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) from 3M's production lot number 501, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but concludes that no reliable conclusions can be drawn due to variability in results and methods used.
|
1981 |
AR226-0741
|
bBK4xjwe1rdbde68e4wNpBeXk |
18 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing perfluorooctanesulfonate (PFOS) as part of the test substance, FC-203C, which is composed of various chemicals including 1.47% PFOS, and outlines the testing methods and conditions.
|
1981 |
AR226-0742
|
MGKJaaoE44em20VKn1b5q6NXa |
14 |
|
The document details a toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M on the aquatic plant species Selenastrum capricomutum, using a 96-hour exposure period to assess algal cell counts and dry weights, although the test sample's concentration of impurities may affect the accuracy of the toxicity data.
|
1981 |
AR226-0744
|
NG0kbzJML7EZm9d9YjZVDG1pQ |
10 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic invertebrate Daphnia magna, indicating that the results pertain to the mixture rather than the fluorochemical component alone.
|
1981 |
AR226-0745
|
5Lr1qDDYKJX9RkwkyOrmV6KMR |
3 |
|
The document details an activated sludge respiration inhibition test conducted on a mixture containing perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating the test sample's composition and preparation methods, but notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1981 |
AR226-0746
|
g39XJ2zz6QyoQ5gNznQmnXOa |
5 |
|
The document presents fluorine measurement data for employees with PFOS exposure at a facility from 1981 to 1997, highlighting the mean fluorine levels and the number of measurements taken per employee over the years.
|
1981 |
AR226-0176
|
BRzaz0vz5gQ7x4jnpK6BJ1NJJ |
12 |
|
The document reports on an activated sludge respiration inhibition test conducted on a mixture containing 0.73% PFOS, produced by 3M, which found no acute inhibitory effect on activated sludge respiration rate at a concentration of 1,000 mg/L.
|
1981 |
AR226-0802
|
2NbmJoM36NbbzEXdMYXrRE695 |
6 |