|
The document includes an exploratory 28-day oral toxicity study on PFOS and other chemicals, submitted by 3M under a claim of confidentiality, detailing the effects of these substances in rats.
|
2000 |
AR226-0153
|
Raq84pYqY9vovD7v35930BpEV |
1 |
|
The document contains various studies and reports related to the pharmacokinetics and skin absorption of perfluorooctane sulfonate (PFOS) conducted by 3M, including multiple animal studies and analytical data submitted to the EPA.
|
2000 |
AR226-0154
|
20rJGqmaQR7J7n6qkje8B0D6 |
6 |
|
The document is a laboratory report from 3M Environmental Laboratory detailing a study on the aqueous photolytic degradation of Perfluorooctanoic Acid (PFOA), which does not comply with US EPA Good Laboratory Practices but has undergone internal quality assurance audits.
|
2000 |
AR226-1030
|
g285jQr1041B9yV5BDMnxMvY3 |
148 |
|
The document is a supplemental submission detailing ongoing studies, specifically a pharmacokinetic study of perfluorooctanesulfonyl fluoride (POSF) in rats, referenced by 3M.
|
2000 |
AR226-0979
|
b5oqy566rX53KY0xb2Mrk4M86 |
1 |
|
This document is a supplemental submission detailing various studies related to N-ethyl perfluorooctane sulfonamidoethanol (N-EtFOSE) and PFOS, including acute toxicity, pharmacokinetics, and teratology studies conducted by 3M and other laboratories, along with a correction to the indexing of a previous letter.
|
2000 |
AR226-0979
|
Gm7db38g1NrvVO1qKrqg19wMn |
1 |
|
This document is a final report on an analytical study conducted by 3M, which investigates the pharmacokinetics of the perfluorinated compound FC-99 (T-6053) in rabbits, finding that fluorine was detected in liver tissue after a single intravenous dose of 20 µg/kg but not at lower doses, indicating that the perfluorooctanesulfonate
|
2000 |
AR226-0157
|
rx8RRqQm7JVDjV78zevE00Z9E |
88 |
|
This document from 3M provides serum measurements of perfluorooctanesulfonate (PFOS) from two pharmacokinetic studies in rats, detailing the analytical results and offering assistance to the EPA in understanding the toxicological data.
|
2000 |
AR226-0160
|
zQXzQLzraLDVmbOo1mGV5Gp67 |
22 |
|
The document is a final report from 3M Environmental Laboratory detailing a single-dose dermal absorption/toxicity study of the perfluorinated compound FC-99 (T-6053) in rabbits, which found no significant differences in total organic fluorine levels between treated and control groups after 28 days.
|
2000 |
AR226-0158
|
XzxgyX81q28oNEg66a21qeXyw |
135 |
|
This document is a supplemental submission detailing acute toxicity studies and pharmacokinetic research related to N-EtFOSA (N-ethyl perfluorooctanesulfonamide) and PFOS, including corrections to previously submitted bibliographic entries and ongoing research at the University of Minnesota.
|
2000 |
AR226-0979
|
KR6J71N66rdddazK6gedVz3D6 |
1 |
|
This document is a supplemental submission regarding a pharmacokinetic study of Perfluorooctane Sulfonamide (PFOSA) in rats conducted by 3M, including references to interim reports and pending laboratory findings.
|
2000 |
AR226-0979
|
wgYQ4oZJay10Nyo83BqxpeQeJ |
1 |
|
The document is a supplemental submission regarding PFOSAA (Perfluorooctane sulfonylamido (ethyl)acetate) and includes references to various studies on acute toxicity and serum half-lives related to PFOS, as part of a medical surveillance and epidemiologic assessment.
|
2000 |
AR226-0979
|
XOjvX2bZdzv4Xmxmp1aY7m94R |
1 |
|
The document is a supplemental submission regarding PFOA (Perfluorooctanoic acid) and PFOS (Perfluorooctane sulfonate), detailing findings related to medical surveillance, epidemiology, and acute toxicity from research conducted in 2000.
|
2000 |
AR226-0979
|
vBpXR9mB5Dz5XpLwo4oyqNXbY |
2 |
|
The document outlines research proposals and studies conducted by Kendall B. Wallace at the University of Minnesota Duluth, focusing on the biochemical and molecular mechanisms of perfluoroalkyl sulfonamides, particularly perfluorooctane sulfonate (PFOS), with the aim of establishing methods to monitor health risks associated with exposure to perfluoroalkyl acids and their derivatives.
|
2000 |
AR226-0165
|
gLDeLYXJzEM8JmbDLV2DmaxQ |
12 |
|
This report details the effects of a single acute dose of PFOS on catalase and acylCoA oxidase gene expression and enzyme activity in liver tissue from rats and guinea pigs, indicating the methodology and analysis used to assess these impacts.
|
2000 |
AR226-0171
|
XLg3bB1ORp2EgNB6pQr03oLG |
6 |
|
The document discusses various studies and analyses related to perfluoroctane sulfonate (PFOS) in human sera, including blood testing results from Decatur workers and children, highlighting the relationship between organic fluorine concentrations in blood and exposure levels.
|
2000 |
AR226-0174
|
rxaKdJRQM1611BdzqVw98QvO7 |
7 |
|
The document is a final report of a pilot teratology study in rats (Project No. 154-158) conducted by Hazleton Laboratories for 3M, focusing on the effects of perfluoroctane sulfonate (PFOS).
|
2000 |
AR226-0173
|
QgQw2OVa6V40dNvmXdEnR1yQ5 |
48 |
|
The document is a supplemental submission detailing the fluorochemical characterization of surface water samples from multiple locations, including Columbus, GA, Cleveland, TN, Decatur, AL, Mobile, AL, Pensacola, FL, and Port St. Lucie, FL, conducted by Centre Analytical Laboratories, Inc. and Battelle Memorial Institute, focusing on perfluorinated compounds.
|
2000 |
AR226-0979
|
85y0EKwL53KN9y4wQGYxGvQ2Z |
1 |
|
3M conducted photolysis studies on PFOS and PFOA to assess their photolytic stability under environmentally relevant conditions, finding no evidence of direct photolysis and no degradation products in indirect photolysis, while estimating a minimum indirect photolytic half-life in an iron-rich matrix.
|
2000 |
AR226-1030
|
kD7bQ212z1Xbz3D1Kw3LbRBD0 |
2 |
|
3M conducted photolysis studies on PFOA and PFOS to assess their photolytic stability under environmentally relevant conditions, finding no evidence of direct photolysis and no degradation products in indirect photolysis, although an estimated minimum indirect photolytic half-life was calculated in an iron-rich matrix.
|
2000 |
AR226-1030
|
qd9yrZkY9j79DgBrB260n9xN5 |
2 |
|
The document outlines the design and methodology of a Multi-City study submitted to 3M Environmental Laboratory, aimed at assessing the dispersion of fluorochemical compounds, including those produced by 3M, in the environment and their potential impact on human exposure through food and drinking water.
|
2000 |
AR226-1030
|
Qk1kKowEZ7RR84Zw9Kewwggg5 |
7 |
|
Pace Analytical Services, Inc. conducted resampling for PFOS, PFOSA, POAA, PFHS, and TFA in Port St. Lucie, Florida, under contract with 3M to confirm baseline data from a previous study conducted in July 1999.
|
2000 |
AR226-0979
|
061emG15Z68DVomj2bJXe0vXJ |
13 |
|
The document summarizes a report by Battelle Memorial Institute estimating the waste streams of PFOS and related sulfonated perfluorochemicals from 3M manufacturing and supply chain facilities, highlighting that the estimates are based on conservative assumptions and questioning the degradation of PFOS, which has not been detected as a degradation product in studies.
|
2000 |
AR226-0979
|
Ve5BwB7e30NywbDXjRm4xjng |
11 |
|
3M submitted new and previously unsubmitted health effects research data on perfluorooctane sulfonates (PFOS) and N-ethyl FOSE, including updated analytical reports from monkey and rat studies, to the EPA as part of their ongoing dialogue regarding fluorochemistry.
|
2000 |
AR226-0979
|
GkryrjGrQ2o7xewX7BM9qVLr |
7 |
|
3M is reporting to the EPA the draft results of a retrospective cohort mortality study of workers at its Decatur, Alabama facility, focusing on perfluorooctane sulfonyl fluoride (POSF)-based production processes, which found no statistically significant elevations in mortality ratios among employees, consistent with previous studies.
|
2000 |
AR226-0979
|
0695Dwpjx7KkxmgKKXOxjnGxd |
2 |
|
3M submitted a TSCA 8(e) notice to the EPA regarding a 2-year rat feeding study on N-Ethyl perfluorooctylsulfonamido ethanol (N-EtFOSE), indicating a statistically significant increase in benign liver tumors in high dose female rats, corroborating earlier findings.
|
2000 |
AR226-0979
|
QJQEpYGLv3RrbN5494vQ0Vaz7 |
2 |
|
The document is a report amendment regarding Protocol 418-009 for a combined oral fertility, developmental, and perinatal/postnatal reproduction toxicity study of N-EtFOSE in rats, indicating a correction to the dosage administration notation without affecting the study results.
|
2000 |
AR226-0979
|
9L4bjrY7BDx6qyv3nB7XgxJw7 |
3 |
|
3M submitted a TSCA 8(e) substantial risk notice to the EPA reporting that a 13-week dietary study on N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE) in rats indicated liver effects and reduced body weights at higher doses, with a no-observable adverse-effect level (NOAEL) identified at 3ppm.
|
2000 |
AR226-0979
|
5Rq92BXk65q5mDD2DOn7yjz5 |
2 |
|
The document outlines ongoing studies related to Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) being conducted by Covance Laboratories and 3M, including a 104-week dietary chronic study in rats and a 26-week capsule toxicity study in cynomolgus monkeys, with interim data provided for both.
|
2000 |
AR226-0179
|
n9MBbQDvq1DOozBoZzQeEJZqX |
12 |
|
This document outlines a research project by 3M, led by Deanna J. Luebker, aimed at investigating the mechanism by which perfluorooctane sulfonic acid (PFOS) induces adverse effects on peri-/postnatal development in rats, specifically through the inhibition of HMG-CoA reductase and potential mitigation of toxicity via mevalonate co-administration.
|
2000 |
AR226-0183
|
om5JbrNwQe5G1L7QXjYzdaYy3 |
16 |
|
The document outlines ongoing environmental studies on perfluorooctanesulfonates (PFOS) being conducted by various laboratories, including 3M Environmental Laboratory and Wildlife International, with expected completion dates for various toxicity tests and degradation studies in 2000.
|
2000 |
AR226-0184
|
z2zBg6wapDkpDdEZ84GZnpjz |
12 |
|
The document is a final report from Covance Laboratories detailing a L5178Y TK +/' Mouse Lymphoma Forward Mutation Assay conducted for 3M, which confirms compliance with Good Laboratory Practice regulations and indicates no deviations that would affect the study's integrity.
|
2000 |
AR226-0979
|
jm1Nxo0EQODgy3bj69Nd5nMgk |
29 |
|
The document outlines a planned one-generation reproduction study of perfluorooctane sulfonate (PFOS) in rats, focusing on pharmacokinetic analysis and involving various dose groups to assess the effects on pregnant rats and their pups.
|
2000 |
AR226-0192
|
5D95o5K9RVdVq0mGXeV1bZ4m4 |
5 |
|
This document outlines a draft study protocol for a one-generation reproduction study of PFOS in female Harlan CD rats, aiming to investigate whether co-administration of mevalonic acid or cholesterol can mitigate adverse maternal and fetal effects observed in a previous study, while also refining the no observed effect level (NOEL).
|
2000 |
AR226-0193
|
jXLRaDrO3Nk4aa2RMJ5NmwRk |
5 |
|
The document provides data from 1974 environmental studies conducted by 3M on the acute toxicity of perfluorooctanesulfonate (PFOS) ammonium salt (FC-93) to fathead minnows, including details on the test substance composition and experimental conditions.
|
2000 |
AR226-0194
|
9JwgoZq3GYzwpbRz0bvqG7Z83 |
11 |
|
The document lists various acute toxicity studies conducted by Biosearch Inc. and Riker Laboratories on perfluorooctane sulfonate (PFOS) and related compounds, detailing the test subjects, methods, and dates of the studies.
|
2000 |
AR226-0197
|
rxKqzo06GgbMBXLQEJL2JDD2E |
2 |
|
This document is an attachment to a letter discussing published studies on perfluorooctanesulfonates (PFOS) and perfluorooctanoic acid (PFOA), highlighting various environmental and toxicological research findings related to these perfluorinated compounds.
|
2000 |
AR226-0198
|
ZB9D6EY1vv9KOb4QbKk4kLYR0 |
2 |
|
3M is providing the EPA with additional information on perfluorooctylsulfonate (PFOS) salts, including their chemical designations and applications, as part of ongoing discussions regarding fluorochemistry.
|
2000 |
AR226-0200
|
per6mrMgkDzMRGK4JxVogOkZ6 |
3 |
|
This is a letter from Latham & Watkins to Dr. Charles Auer at the EPA, enclosing an analytical report from 3M's environmental monitoring program regarding perfluorinated materials, specifically detailing biosphere sampling and analysis results dated May 10, 2000.
|
2000 |
AR226-0201
|
QkVxR759XNK3GvxxprZxRvKaR |
2 |
|
3M is providing supplemental information to the EPA regarding perfluorooctane sulfonates (PFOS), including executive summaries and a summary of a 26-week toxicity study in cynomolgus monkeys, to complete their previous submission.
|
2000 |
AR226-0203
|
93kqxkYX1G5ZZqL0rx2NZGa4L |
8 |
|
3M is providing the EPA with additional information on perfluorooctane sulfonates and related compounds, including various CAS numbers, as part of ongoing discussions regarding fluorochemistry, while noting that some information is confidential business information.
|
2000 |
AR226-0204
|
xzwGQ6qyve3yw3zqjNZ51R5yE |
51 |
|
The document contains a summary of acute toxicity studies related to perfluorooctane sulfonylamido (ethyl)acetate (PFOSAA) conducted by Biosearch, Inc. and Riker Laboratories for 3M, detailing various toxicity tests on rats and rabbits from 1978 to 1982.
|
2000 |
AR226-0216
|
aK3bX7308X2J7Qrowzzd1dna |
5 |
|
The document contains various studies and reports from Hazelton Laboratories America, Inc. regarding the acute toxicity, genotoxicity, and pharmacokinetics of perfluorodecanesulfonate (PFDS) and other perfluorooctane sulfonate-related compounds, primarily conducted for 3M.
|
2000 |
AR226-0228
|
zdD75BOKoDzK77dpm6QzYQMQ7 |
17 |
|
This document is a final report of a pharmacokinetic study conducted by 3M on the test substance FC-129 (T-6054), which found that perfluorooctanesulfonate was a significant component of total organic fluorine detected in rabbit liver samples 48 hours after intravenous dosing.
|
2000 |
AR226-0226
|
0gNjxmw0xm92awVxbLgxNKGLn |
96 |
|
Pace Analytical Services, Inc. conducted resampling for the Port St. Lucie Multi-City Study under contract with 3M to confirm baseline information on fluorochemicals, specifically PFOS, PFOSA, POAA, PFHS, and TFA, originally collected in July 1999.
|
2000 |
AR226-1030
|
zQGXR8MeY5kv0drBgJ0jvDpqz |
13 |
|
This document is a final report on a 4-week range-finding dietary toxicity study of N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE, T-6314) conducted on rats, sponsored by 3M and performed by Covance Laboratories.
|
2000 |
AR226-0979
|
zQ10XOBZawXbmVmgo7b7QMr6m |
373 |
|
This document is a final report on a 13-week dietary toxicity study of N-Methyl Perfluorooctanesulfonamido Ethanol (N-MeFOSE, T-6314) conducted in rats, sponsored by 3M and performed by Covance Laboratories.
|
2000 |
AR226-0979
|
b5rrYK27L1QmKxgQKjB2eOd4y |
560 |
|
Pace Analytical Services, Inc. conducted a multi-city food study for 3M to estimate the dietary intake of fluorochemicals, including PFOA and PFOS, by collecting food samples from three study cities (Pensacola, FL; Decatur, AL; Mobile, AL) and three control cities (Port St. Lucie, FL; Cleveland, TN; Columbus, GA).
|
2000 |
AR226-1030
|
wOYxXrB6NndGQJVGz4BO1aOE |
60 |
|
This report details the accumulation of perfluorooctanesulfonate (PFOS) and related fluorochemicals, including perfluorooctanoic acid (PFOA), in the livers of mink and river otters, finding PFOS present in all mink samples with a maximum concentration of 4800 ng/g, while PFOA was detected in less than 10
|
2000 |
AR226-1030
|
Moood1YNNdgdDLdVL3qnkr9Ky |
14 |
|
This report details a monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanoic acid (PFOA), and related fluorochemicals in fish tissues, revealing the highest PFOS concentration of 923 ng/g in fish from Belgium and 297 ng/g in carp from Michigan, while FOSA, PFOA, and PFHS were rarely
|
2000 |
AR226-1030
|
85zNn67nBKGR8rk13DNN2GEEB |
38 |
|
This document reports on a study measuring concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in oysters from the Gulf of Mexico and Chesapeake Bay, finding PFOS in 51 of
|
2000 |
AR226-1030
|
93Bnn6JdvqELoMYgY8LvmJEeR |
19 |
|
This report presents the findings of a global monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHS) in fish-eating water birds, revealing significant concentrations of PFOS in various species, particularly
|
2000 |
AR226-1030
|
oM92x077J844Eo2rR913eeLXE |
60 |
|
This report details a global monitoring survey of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and related fluorochemicals in marine mammals, revealing that PFOS was commonly detected in liver and blood samples from various locations, with the highest concentrations found in bottlenose dolphins and ringed seals, while PFOA was rarely
|
2000 |
AR226-1030
|
8nYrxvEVBkb6LDOrEkGND4jk |
56 |
|
The document summarizes multiple studies conducted by the University of Minnesota on the serum levels of fluorochemicals, including PFOA and PFOS, among workers at 3M facilities and in children's sera, highlighting findings from medical surveillance and epidemiological analyses.
|
2000 |
AR226-1030
|
MyQp4mdb7RgqbRDD776MqwBL |
2 |
|
The document details an experiment using thermospray mass spectrometry to assess the volatility of FC-95 and FC-143, specifically investigating their vapor pressure at room temperature and their removal from various solutions when air is bubbled through them.
|
2000 |
AR226-1030
|
qo5OJy8OBrRGLDwwYnZp4q1M |
20 |
|
The document outlines the design and methodology of a Multi-City study submitted to 3M Environmental Laboratory, aimed at assessing the dispersion of fluorochemical compounds, including those produced by 3M, in the environment and their potential impact on human exposure through water and food sources.
|
2000 |
AR226-1030
|
2qd3nRX3VeZMb0EZOz4KQ4D66 |
7 |
|
The document is an environmental laboratory report detailing the testing results for surfactants, specifically FC-95 and Sultone Foamer, with the initial results for FC-95 being questioned for accuracy and subsequently retested, showing significantly higher concentrations.
|
2000 |
AR226-1030
|
R6wqgGxx6vVNeY45XK3YBREn |
9 |
|
The document details a study on the microbial metabolism and biodegradation of Perfluorooctane Sulfonate (PFOS), conducted by Springborn Laboratories and submitted to 3M Environmental Laboratory, completed on October 31, 2000.
|
2000 |
AR226-1030
|
dQ3Q01vDo7abNXOpxZxEp2e1Q |
21 |
|
Pace Analytical Services, Inc. conducted resampling for the Port St. Lucie Multi-City Study under contract with 3M to confirm baseline information on fluorochemicals, specifically targeting PFOS, PFOSA, POAA, PFHS, and TFA, originally sampled in July 1999.
|
2000 |
AR226-1030
|
2rk5v0qOQrM40583KwYvZ53r |
13 |
|
This final report from 3M Environmental Laboratory details a dermal absorption and toxicity study of the perfluorinated compounds FC-129 (T-6051 and T-6054) in rabbits, finding that approximately 0.2% of the highest administered dose of FC-129 (12.8 mg/kg) was absorbed into the liver after 28 days.
|
2000 |
AR226-0225
|
GEQp32jj5LXb5RemELd26wyq |
151 |
|
The document contains attachments to a letter discussing various acute toxicity and genotoxicity studies related to N-ethyl perfluorooctanesulfonamide (N-EtFOSA) and other perfluorooctane sulfonate-related compounds conducted by Riker Laboratories and Coming Hazelton, primarily focusing on tests performed on albino rats.
|
2000 |
AR226-0236
|
VGJv4j0pByo37ob8YXKer9n7g |
15 |
|
The document is a final report from 3M Environmental Laboratory detailing a pharmacokinetic study of the perfluorinated compound FC-120 (T-6052) in rabbits, which found detectable organic fluorine levels in liver samples only at higher doses.
|
2000 |
AR226-0235
|
ZJRBb79xa28z2opQK1LNKrEKd |
143 |
|
The document details a study conducted by Pace Analytical Services, Inc. under contract with 3M to collect food samples from three study cities and three control cities to estimate the dietary intake of fluorochemicals, including PFOA and PFOS, by local residents.
|
2000 |
AR226-1030
|
B5azb4Z2od2odv6qJey6QKvVE |
60 |
|
This document is a study report from 3M Environmental Laboratory detailing a Soil Adsorption/Desorption Study of Potassium Perfluorooctanesulfonate (PFOS), conducted in compliance with TSCA Good Laboratory Practice standards.
|
2000 |
AR226-1030
|
JNoZZme5Jwm7BaMz3qyER7J0a |
758 |
|
This report details the accumulation of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in the livers of mink and river otters, finding PFOS present in all mink samples with a maximum
|
2000 |
AR226-1030
|
K61bw0XGnMnXK9o9JnERbj3XX |
14 |
|
This report details a monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanoic acid (PFOA), and related fluorochemicals in fish tissues, finding the highest PFOS concentration at 923 ng/g in fish from Belgium, while PFOA and other fluorochemicals were rarely detected.
|
2000 |
AR226-1030
|
mp2Zq3GadLG4gdBYkjkwv2oOB |
38 |
|
This document reports on a study measuring concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in oysters from the Gulf of Mexico and Chesapeake Bay, finding PFOS in 51 of
|
2000 |
AR226-1030
|
emk4Or2gQQvwdNqxNE8V2VrYy |
19 |
|
This report details a global monitoring survey of perfluorooctane sulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in marine mammals, revealing that PFOS was commonly detected in liver and blood samples from various locations,
|
2000 |
AR226-1030
|
QKkXxYL262Kq9YRyQgDnZ61k |
56 |
|
This report details a global monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHS) in fish-eating water birds, revealing significant concentrations of PFOS in various bird tissues, particularly noting high
|
2000 |
AR226-1030
|
kmaXkX88GazVQZpm9a1LkG13n |
60 |
|
This document is a study report on the aerobic soil biodegradation of Perfluorooctane Sulfonate (PFOS), conducted by Springborn Laboratories and submitted to 3M Environmental Laboratory, completed on October 31, 2000.
|
2000 |
AR226-1030
|
GKvJOm5KGZY1wxRMJj6ex2kVn |
17 |
|
The document is a study report on the microbial metabolism (biodegradation) of Perfluorooctane Sulfonate (PFOS), completed by Springborn Laboratories and submitted to 3M Environmental Laboratory.
|
2000 |
AR226-1030
|
5MMV9JKqY2z5Bke7Qe2XEwyN |
36 |
|
This document reports on a study conducted by Springborn Laboratories, Inc. on the anaerobic biodegradation of perfluorooctane sulfonate (PFOS), completed on October 31, 2000, for 3M Environmental Laboratory.
|
2000 |
AR226-1030
|
qdpvJaaMqaeORXxY2Ba1RjxEG |
16 |
|
The document describes an experiment using thermospray mass spectrometry to investigate the volatility of FC-95 and FC-143, specifically testing their vapor pressure and removal from solutions when air is bubbled through them.
|
2000 |
AR226-1030
|
mBv7yM9DGGO66r1R3ggKOY0g |
20 |
|
The final report from 3M's Environmental Laboratory indicates that a single-dose dermal absorption study of the perfluorinated compound FC-120 (T-6052) in rabbits showed no significant organic fluorine absorption at the highest dose of 1000 mg/kg, rendering the pharmacokinetic assessment unsuccessful.
|
2000 |
AR226-0234
|
Vdrj8Vqbxby17jw06b54rxng |
183 |
|
The document contains various toxicity and genotoxicity study reports on N-methyl perfluorooctanesulfonamide (N-MeFOSA) conducted by Hazleton Laboratories for 3M, detailing acute oral toxicity, dermal irritation, eye irritation, and mutagenicity assays.
|
2000 |
AR226-0242
|
8RXa0E4QG0wqaRRqJGmr5OEe |
51 |
|
The document contains attachments related to studies and information on perfluorooctane sulfonate (PFOS) and its related compounds, including acute toxicity, genotoxicity, and repeated-dose toxicity studies conducted by Hazelton Laboratories and International Research and Development Corporation.
|
2000 |
AR226-0249
|
V3QzppbGeaeyb9zwe0RKeQbL8 |
20 |
|
The document is an archived final report detailing laboratory analyses of surfactants, specifically FC-95 and Sultone Foamer, with results indicating high concentrations of these substances, prompting a request for retesting due to initially unexpected high values.
|
2000 |
AR226-1030
|
L5pn5RBb1evLxMQ0Qq24na03 |
9 |
|
This document is a study report on the microbial metabolism (biodegradation) of perfluorooctane sulfonate (PFOS), conducted by Springborn Laboratories and submitted to 3M Environmental Laboratory.
|
2000 |
AR226-1030
|
XOK51B8oanYYRkKQBymonde9J |
36 |
|
The document reports on a study conducted by Springborn Laboratories, Inc. on the aerobic soil biodegradation of perfluorooctane sulfonate (PFOS), completed on October 31, 2000, for 3M Environmental Laboratory.
|
2000 |
AR226-1030
|
RJrZ2XkDKYMB0QRyx0GJK1bg8 |
17 |
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This document reports on a study conducted by Springborn Laboratories, Inc. on the anaerobic biodegradation of Perfluorooctane Sulfonate (PFOS), submitted to 3M Environmental Laboratory, with completion dated October 31, 2000.
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2000 |
AR226-1030
|
8ObgRD3pyGL6jJ8JqR2D3Mbe |
16 |
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The document is a study report on the microbial metabolism (biodegradation) of Perfluorooctane Sulfonate (PFOS), completed by Springborn Laboratories for 3M Environmental Laboratory, detailing the methodology and findings related to PFOS degradation.
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2000 |
AR226-1030
|
x1G0JjQJ8xNwE4qV6E0DJ8Y21 |
21 |
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The document is a final report on a flow-through bioconcentration test of perfluorooctanesulfonate (PFOS) conducted with bluegill fish (Lepomis macrochirus) by Wildlife International, Ltd. for 3M Corporation, adhering to Good Laboratory Practice Standards.
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2000 |
AR226-1030
|
Oz8b3ynD0qLKpvDVVmnReqeQM |
129 |
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The document details an experiment using thermospray mass spectrometry to assess the volatility of FC-95 and FC-143, specifically investigating their vapor pressure at room temperature and their removal from various solutions when air is bubbled through them.
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2000 |
AR226-1030
|
zodkaRGDewg11z9REVEROvQV6 |
20 |
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The document is a final report on a 7-day toxicity test of PFOS (perfluorooctanesulfonic acid) using duckweed (Lemna gibba G3), conducted by Wildlife International, Ltd. for 3M Corporation, and completed on March 26, 2001, in compliance with Good Laboratory Practice standards.
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2000 |
AR226-1030
|
rpbQ4aMMw7pJg0XV8yQwp2x5G |
47 |
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The document is a final report on a 96-hour toxicity test of PFOS conducted by Wildlife International, Ltd. for 3M Corporation, indicating compliance with Good Laboratory Practice standards and detailing the study's initiation and completion dates.
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2000 |
AR226-1030
|
dYkbE38kQ0GjpEE38eOLKxkKb |
56 |
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This final report details a 96-hour toxicity test of PFOS conducted by Wildlife International, Ltd. for 3M Corporation, using the marine diatom Skeletonema costatum, and confirms compliance with Good Laboratory Practice Standards despite some exceptions in substance characterization.
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2000 |
AR226-1030
|
6BrBaNpbpNjJv1KLE09pym5zE |
54 |
|
This final report details a 96-hour toxicity test of PFOS conducted on the freshwater alga Anabaena flos-aquae by Wildlife International, Ltd. for 3M Corporation, with study completion on June 6, 2001, and notes compliance with Good Laboratory Practice standards despite some exceptions.
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2000 |
AR226-1030
|
ko4rBGL5ERvLdp8EwvReDrvq |
57 |
|
The document is a final report of a frog embryo teratogenesis assay (FETAX) conducted by Wildlife International, Ltd. for 3M Corporation, assessing the effects of PFOS, with noted non-compliance with Good Laboratory Practice standards during the study.
|
2000 |
AR226-1030
|
jg5gdKQjZVQ588vG1pqE6pOLk |
181 |
|
The document details a biodegradation study of perfluorooctanesulfonate (PFOS) conducted by Springborn Laboratories, Inc., which evaluated the toxicity and biodegradability of PFOS using acclimated activated sludge from a wastewater treatment plant over a 16-week period.
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2000 |
AR226-1030
|
YD42XM3r91BLpOpdjQzzrLGj0 |
4 |
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The document details a biodegradation study of perfluorooctanesulfonate (PFOS) conducted by Springborn Laboratories, Inc., which assessed the compound's degradation in aerobic soil and sediment cultures over a 20-week period, reporting biomass levels and test conditions.
|
2000 |
AR226-1030
|
bBJdKXLmQ74wkbqm4vo0JaYb6 |
2 |
|
The document details a biodegradation study of perfluorooctanesulfonate (PFOS) conducted by Springborn Laboratories, Inc., using anaerobic sludge from a wastewater treatment plant, which found the test substance to have a purity of 86.9% and involved a 56-day incubation period to assess its degradation.
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2000 |
AR226-1030
|
k6vKdxx6bJ0Q03qMZndzjJMqV |
2 |
|
This document details a revised dietary acute study on the effects of perfluorooctanesulfonate (PFOS) on mallard ducks, including tissue analysis and findings related to the substance's purity and testing methodology.
|
2000 |
AR226-1030
|
ZBx1D4w0547Ornen6d8Rvv3M7 |
9 |
|
3M conducted photolysis studies on PFOA and PFOS to assess their photolytic stability under environmentally relevant conditions, finding no evidence of direct photolysis and no degradation products, while estimating a minimum indirect photolytic half-life in an iron-rich matrix.
|
2000 |
AR226-1030
|
GmodNVRLV5a0d6EKQ3xEzbG9v |
2 |
|
The document details a study on the stability of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol), produced by 3M, focusing on its photolytic degradation in various water matrices under controlled light conditions, with results indicating its breakdown products.
|
2000 |
AR226-1030
|
pejjMqmMKKdJz1yN5gVpXB4GD |
2 |
|
The document is a laboratory report from 3M Environmental Laboratory detailing a study on the aqueous photolytic degradation of Perfluorooctanoic Acid (PFOA), which does not comply with US EPA Good Laboratory Practices but has undergone internal quality assurance audits.
|
2000 |
AR226-1030
|
6bdJ9NGweZ21gkee7eek7kQad |
148 |
|
The document details a study on the stability of perfluorooctanoic acid (PFOA) ammonium salt under photolysis conditions, conducted by 3M in 2001, which found no conclusive evidence of degradation or breakdown products.
|
2000 |
AR226-1030
|
v1r181KDXan99ZRek5v31mOQZ |
2 |
|
The document reports that no evidence of direct or indirect photolysis of perfluorooctanesulfonate (PFOS) was observed in water under various testing conditions conducted by 3M in 2001.
|
2000 |
AR226-1030
|
8O035zzV8XrNvQpg6GR3QMQMe |
2 |
|
The document is a laboratory report from 3M Environmental Laboratory detailing a study on the aqueous photolytic degradation of Potassium Perfluorooctane Sulfonate (PFOS), indicating that the study does not comply with US EPA Good Laboratory Practices but was audited by 3M's Quality Assurance Unit.
|
2000 |
AR226-1030
|
EvLoG3r2xpey3GxOOMjjNjRvj |
163 |
|
The document is a laboratory report from 3M detailing screening studies on the aqueous photolytic degradation of 2-(N-Ethylperfluorooctanesulfonamido)-ethyl alcohol (N-EtFOSE Alcohol), conducted in accordance with specific EPA and OECD guidelines, although not compliant with Good Laboratory Practices.
|
2000 |
AR226-1030
|
nvXobg4Rg97Dey7p6rjYbZOa |
166 |
|
The document is a report on an 18-day aerobic biodegradation study of perfluorooctanesulfonate-based chemistries conducted by 3M and Pace Analytical Services, detailing the project's initiation, completion, and authorship.
|
2000 |
AR226-1030
|
NeXrzJ9wZa7RZvQz5qw1YM5pg |
39 |
|
This is a biodegradation study report prepared by Pace Analytical Services, Inc. for 3M, focusing on the aerobic biodegradation of W-EtFOSE alcohol using microbial activity from municipal wastewater treatment sludge.
|
2000 |
AR226-1030
|
1gd8ddaxabvXKE59JwXxdaZ3j |
56 |