|
The document reports on an eye irritation test conducted on rabbits using a waxy test material submitted by E. I. du Pont de Nemours Company, indicating that the material caused only transient mild conjunctivitis with no lasting ocular effects.
|
— |
AR226-2869
|
LpdVy30ooXn5V5qRap9Z5GJrX |
2 |
|
The document reports on a primary irritation and sensitization test conducted by E. I. du Pont de Nemours and Company on a test material, likely related to perfluorinated compounds, using guinea pigs to assess skin reactions, with results indicating no significant irritation or sensitization responses.
|
— |
AR226-2870
|
bBrY6rxDMGqDKmRnBExdx4bwD |
2 |
|
This is a Haskell Laboratory report (No. 422-78) from du Pont de Nemours and Company detailing a skin irritation test conducted on rabbits, with results indicating no irritation.
|
— |
AR226-2871
|
8VOZb2LJj99gyb0r0x69p8oZZ |
1 |
|
The document reports on a subacute oral toxicity test of PFOA conducted by E. I. du Pont de Nemours and Company, indicating significant pathological changes in the liver, spleen, and thymus of male ChR-CD rats, along with notable weight loss compared to the control group.
|
— |
AR226-2873
|
44JNmn1GbVzEVpvQ3J2kNOZgQ |
7 |
|
The document reports on a study conducted by Haskell Laboratory where PFOA was administered orally to young adult ChR-CD male rats at a dosage of 5,000 mg/kg/day for ten days, resulting in clinical signs of toxicity including alopecia, weight loss, and necrosis of various tissues, with some effects expected to be reversible after a recovery period.
|
— |
AR226-2874
|
zzLG9vNp1LyddKGL6K2806BRz |
2 |
|
The document is a revised report from Haskell Laboratory detailing a study on the effects of an aqueous solution of a perfluorinated compound administered at a dosage of 3,400 mg/kg/day to young adult ChR-CD male rats, which resulted in liver hypertrophy and weight changes, indicating potential reversibility of the effects with a longer recovery period.
|
— |
AR226-2875
|
yrnRaaB35oGapx0JLq3ZE91eD |
6 |
|
The document reports on a series of oral subacute toxicity tests conducted on male ChR-CD rats using a 50% suspension of a perfluorinated compound, resulting in high mortality rates among test subjects at dosages of 3,400 mg/kg/day and 1,700 mg/kg/day.
|
— |
AR226-2876
|
7Me8zxNBjL6d8KwBOm9p0Zzq8 |
4 |
|
The document reports on primary skin irritation and sensitization tests conducted on guinea pigs using a 20% solution of a test material, which was found to cause no skin irritation or sensitization responses.
|
— |
AR226-2878
|
MJrB2GQLE1jze88MX4kyaB0RV |
2 |
|
The document is a laboratory report from E. I. du Pont de Nemours and Company detailing an oral LD50 toxicity test of a perfluorinated compound, indicating very low toxicity in young adult ChR-CD male rats with an LD50 value of approximately 5,043 mg/kg, and noting various clinical signs observed at different dosage levels.
|
— |
AR226-2879
|
7RkpdKjqmeRzmboLzjv09ENej |
2 |
|
The document reports on an eye irritation test conducted by Haskell Laboratory for Du Pont de Nemours and Company, which found that a 2% solution of an unspecified perfluorinated compound caused very slight conjunctival irritation in rabbits, with no corneal effects observed.
|
— |
AR226-2880
|
d9Z5bnmYoj7jxv8w9D9ej9X9 |
2 |
|
The document reports on an oral LD50 toxicity test of PFOA conducted by Du Pont's Haskell Laboratory, indicating that high doses resulted in significant mortality and clinical signs of distress in rats within a few days post-dosing.
|
— |
AR226-2881
|
MM2e7wo4OzDDRX2RyBNDaqOLL |
2 |
|
The document is a laboratory report from DuPont's Haskell Laboratory detailing an eye irritation test conducted on rabbits using Haskell No. 13,197, which resulted in slight corneal opacity and mild conjunctivitis, with recommendations for flushing the eyes with copious amounts of water.
|
— |
AR226-2882
|
0kR60x4n6MG7VLwMLNgrLVxx |
3 |
|
The document reports that E. I. du Pont de Nemours and Company's material tested for skin irritation and sensitization on guinea pigs showed no irritation or sensitization responses, indicating a low dermatitis hazard from handling the substance.
|
— |
AR226-2883
|
Gm9qXonebB3Xv5Oj49pM5ZpJv |
2 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the inhalation median lethal concentration (LC50) of a test material, likely a perfluorinated compound, using ChR-CDG rats exposed to vapor atmospheres.
|
— |
AR226-2884
|
wg2ZDmyeyra82d0EdMajGZKoJ |
3 |
|
The document reports a skin irritation test on rabbits using an unspecified test material, indicating that it caused mild to slight skin irritation after 24 hours and mild to no irritation after 48 hours, suggesting good industrial hygiene practices in case of skin contact.
|
— |
AR226-2885
|
zopLdzK9oKKpgG4rL1DyMo6dg |
2 |
|
The document reports on a skin irritation test conducted by E. I. du Pont de Nemours and Company on male albino rabbits using an undiluted test material, which resulted in slight erythema after 24 hours but no irritation observed at 48 hours, suggesting minimal skin irritation potential.
|
— |
AR226-2886
|
rBVjzXoEqErJ7jxZDB1p3y2Be |
2 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using undiluted test material on rabbits, finding it to be a mild ocular irritant with transient effects that resolved within one to two days.
|
— |
AR226-2887
|
Yjn1g5a7VrdwdONORGERgLokE |
2 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using a solid test material, which caused mild conjunctivitis in rabbits, indicating it is a mild eye irritant that should be flushed with water if contact occurs.
|
— |
AR226-2888
|
3J2Yx8BxGBQ8GanGKJ4MKLyMO |
2 |
|
The document reports on an acute oral toxicity study conducted by E. I. du Pont de Nemours and Company on an unspecified perfluorinated compound, revealing that the lethal dose in rats exceeds 25,000 mg/kg with only slight weight loss observed at the highest doses.
|
— |
AR226-2889
|
LKZvpQL8wOr7yYKvk5ngdMbK5 |
2 |
|
The document is a report from E. I. du Pont de Nemours and Company detailing an eye irritation test conducted on rabbits using an undiluted test material, which resulted in mild ocular effects and severe discharge in the unwashed eye, with recovery observed within a few days.
|
— |
AR226-2891
|
MGNj3m44rQeXvOMYYXrkgRbYL |
3 |
|
The document reports on a primary skin irritation and sensitization test conducted by E. I. du Pont de Nemours and Company on guinea pigs, indicating that the test material was a skin irritant at a concentration of 25% in distilled water, while showing mild to no irritation at 2.5%.
|
— |
AR226-2892
|
jLaBrwgd7YNmYQz8rkBXymNy |
3 |
|
The document is a Haskell Laboratory report detailing an LD50 toxicity test of a perfluorinated compound conducted by du Pont de Nemours and Company, which found that the compound has an LD50 greater than 25,000 mg/kg, indicating very low toxicity when administered orally to rats.
|
— |
AR226-2893
|
2Dp6a1JbBOoyYRd3pMV8GeJ6 |
2 |
|
The document details a study conducted by Haskell Laboratory for Toxicology and Industrial Medicine to determine the 4-hour inhalation median lethal concentration (LC50) of a perfluorinated compound in male albino Crl:CD rats, specifically focusing on the exposure and analytical methods used during the investigation.
|
— |
AR226-2890
|
44r2ZJjayjrJ4MK9gRybVJEpR |
3 |
|
This document details a study conducted by E. I. du Pont de Nemours and Company to determine the approximate lethal concentration (ALC) of perfluorinated compounds in male Crl:CD rats, focusing on the effects of different process temperatures on toxicity.
|
— |
AR226-2895
|
5O92DE5Gq12xpYmdKeK2qO7e |
4 |
|
The document reports on a skin irritation test conducted by E.I. du Pont de Nemours and Company on New Zealand White rabbits, which found no significant erythema or edema after the application of a PFOA-containing aqueous paste.
|
— |
AR226-2896
|
zdyYoLwLOaNwOOb2pdn0YnEnn |
2 |
|
The document is a subacute inhalation toxicity study conducted by E. I. du Pont de Nemours and Company at the Haskell Laboratory, which tested the effects of repeated inhalation exposure to a specific perfluorinated compound (PFC) vapor on male rats, with exposure concentrations of 1.0 mg/l and 10.0 mg/l over a two-week period.
|
— |
AR226-2894
|
jy4zD8gE5JQDbOvnjvk9kBb1O |
15 |
|
The document reports on an eye irritation test conducted by E. I. du Pont de Nemours and Company using a solid test material, which caused mild to moderate ocular effects, including corneal clouding and conjunctivitis, in both treated rabbits, with both eyes returning to normal after 14 days.
|
— |
AR226-2897
|
VJm092O5jmJ44ZnLQ488LN1pw |
3 |
|
The document reports on an oral LD50 toxicity test for a perfluorinated compound conducted by E. I. du Pont de Nemours and Company, indicating that the substance is moderately toxic with an LD50 value of 2,196 mg/kg in young adult male rats, with various clinical signs of toxicity observed at different dose levels.
|
— |
AR226-2899
|
zQwV8e4MwroxZXoO3mQnqd8k7 |
3 |
|
The Haskell Laboratory report indicates that the material H-14,008, tested by E. I. du Pont de Nemours and Company, exhibited low acute toxicity to fathead minnows (Pimephales promelas) during a 96-hour LC50 study.
|
— |
AR226-2900
|
YpLG3wVBJjV9j1z5aoxYjBOV |
4 |
|
This document outlines a desk study commissioned by the Dutch Ministry of Transport, Public Works, and Water Management, focusing on the environmental behavior, ecotoxicology, and usage of perfluorinated surfactants (PFS), including PFOA and PFOS, in the Netherlands.
|
— |
AR226-2686
|
VGgQJGbqXZMpZLZYar9NQ5pqg |
12 |
|
The document discusses the Telomer Research Program's investigation into the biodegradation potential of 8-2 Telomer B Alcohol, a fluorotelomer intermediate, highlighting its physical-chemical properties and the challenges in testing due to its low water solubility and volatility, while also detailing the preparation of radiolabeled compounds for further studies.
|
— |
AR226-2689
|
KGx78XqoGpn3Y8meKBYOEMyXx |
3 |
|
The document is a final report from DuPont detailing an Activated Sludge Respiration Inhibition Test of Telomer B 8-2 Alcohol, conducted in compliance with OECD guidelines, to assess its environmental impact.
|
— |
AR226-2687
|
2jbmvdQb1EvgZ1B7grBJ7mQy7 |
28 |
|
The document summarizes the screening studies for the biodegradability assessment of 8-2 Telomer B Alcohol, focusing on the challenges of low water solubility and adsorption, and outlines the objectives and methodologies of the Ready Biodegradation and Accelerated Biodegradation tests to identify critical parameters before longer-term studies.
|
— |
AR226-2690
|
pBVqvVKZ1npDMMkdyOnY912ra |
4 |
|
This is a biodegradation study report (Revision 1) prepared by Pace Analytical Services for 3M, focusing on the biodegradation screening of telomer-type alcohols, with project initiation in August 2000 and completion in September 2001.
|
— |
AR226-2688
|
LpXmdXqga4Q43a212ExXMqVwd |
39 |
|
The document outlines a biodegradability study aimed at assessing the potential transformation of telomer-based polymeric products into PFOA during sewage treatment, while addressing the presence of PFOA as an impurity and detailing the testing protocols to be used.
|
— |
AR226-2695
|
kmjY968v0RBO2v03yrXwyjw7J |
4 |
|
The document is a report from DuPont detailing the results of a study on the ready biodegradation of 8-2 Telomer B Alcohol, conducted according to the OECD 301D Closed Bottle Test guidelines, completed on March 20, 2003.
|
— |
AR226-2692
|
EvqNEEmepVMeLg4KxZyJmr85V |
29 |
|
The document is a report by DuPont detailing the aqueous stability of 8-2 Telomer B Alcohol as a function of pH, conducted under the Telomers Research Program sponsored by The Rand Corporation.
|
— |
AR226-2693
|
2qnGjZLMyRYL3Jo1XM553oL35 |
32 |
|
The document is a report by E.I. du Pont de Nemours and Company detailing a preliminary screening study on the accelerated biodegradation of 8-2 Telomer B Alcohol, conducted under OECD guidelines.
|
— |
AR226-2691
|
jBJRbpLDN37wGy4ejZejxEYdQ |
48 |
|
The document reports an oral LD50 toxicity test for a perfluorinated compound conducted by E. I. du Pont de Nemours and Company, indicating that the compound has a low toxicity with an LD50 value of 7,797 mg/kg in young adult Crl:CD male rats, with observed clinical signs including weakness and weight loss.
|
— |
AR226-2901
|
ykoja9nBg0eDrqwOQr6MjqE4n |
3 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Company to determine the inhalation median lethal concentration (LC50) of a test material, revealing that no deaths occurred in male albino rats exposed to atmospheric concentrations as high as 9.6 mg/L.
|
— |
AR226-2902
|
RpKwM6mZaNoa9dv8xRwyxDjpn |
3 |
|
This document reports on a study conducted by E. I. du Pont de Nemours and Company to assess the inhalation toxicity of a substance (likely a perfluorinated compound) in male rats, determining an LC50 value of 35.3 mg/L after repeated exposure.
|
— |
AR226-2903
|
re5Gobrk6m87weKrVwpeQ2NKq |
14 |
|
The document reports an oral LD50 toxicity test for PFOA conducted by E. I. du Pont de Nemours and Company, revealing that the LD50 value in young adult male rats is approximately 916 mg/kg, with various clinical signs observed at different dosage levels.
|
— |
AR226-2905
|
wqYzOMadb2587VBQO01Ro2mJ3 |
2 |
|
The document is a Haskell Laboratory report evaluating the ocular irritancy potential of a chemical, focusing on sources of intralaboratory variability and the effect of dosage volume, with findings indicating significant variability in results from standardized tests.
|
— |
AR226-2904
|
O15zvKG40JyQRQ0rO437ywjLv |
17 |
|
The document reports an oral LD50 toxicity test conducted by E. I. du Pont de Nemours and Co., Inc. on PFOA in young adult male rats, determining the LD50 to be 1,855 mg/kg, with observed clinical signs including weakness, lethargy, and mortality occurring up to 13 days post-dosing.
|
— |
AR226-2910
|
JN96Gb7er8LqXw2LmnB6nxynK |
3 |
|
This document reports on a toxicological study conducted by E. I. du Pont de Nemours and Company, which found that young adult rats administered PFOA at high doses (1,000 mg/kg and 100 mg/kg) exhibited significant clinical signs of toxicity, including weight loss and organ lesions, while lower doses showed no treatment-related effects.
|
— |
AR226-2906
|
a72d2Myb2y3ypqd6MV3LMJRX |
39 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Co., Inc. at the Haskell Laboratory, which determined that the approximate lethal concentration (ALC) of a perfluorinated compound (PFAS) tested is 42 mg/m³ by inhalation, indicating extreme toxicity, while the intravenous lethal dose (ALD) is 500 mg/kg,
|
— |
AR226-2912
|
v5z9rxrNB4NLpwxeErgo1DrR |
6 |
|
This is a Haskell Laboratory report (No. 109-83) detailing the analysis of materials related to a study initiated on December 2, 1982, for DuPont.
|
— |
AR226-2911
|
OED6waB08zJBYpxEbnKxzQrKK |
25 |
|
The document reports on a dermal irritation study conducted by ATOCHEM, which found that the product tested (unspecified perfluorinated compound) caused slight erythema in New Zealand rabbits but was ultimately considered a non-irritant under the experimental conditions.
|
— |
AR226-2914
|
MJE91njD7LQVGk2d2YkEa4vLV |
30 |
|
The document reports on a subchronic inhalation toxicity study conducted by E. I. du Pont de Nemours and Co., Inc. on male rats exposed to perfluorinated compounds at varying concentrations, finding significant pulmonary effects and fatalities at the highest concentration of 10 mg/m³, while lower concentrations showed no adverse effects.
|
— |
AR226-2915
|
baGBXoXkraEDDDXknXNEV2KyZ |
19 |
|
The document summarizes a study conducted by ATOCHEM on the acute oral toxicity of a product administered to male and female rats, finding no lethal effects at a dose of 5000 mg/kg and no evidence of lesions in the animals.
|
— |
AR226-2916
|
p24KXRwqnn22wyXZLYxOYZpda |
33 |
|
The document reports on a study conducted by ATOCHEM, which found that a product caused slight eye irritation in New Zealand rabbits, with reversible reactions observed at the conjunctiva and iris.
|
— |
AR226-2917
|
zJK31R3EaOnoeKz4Rxo7DGvm |
31 |
|
The document is a report from DuPont detailing a study on the adsorption and desorption of ammonium perfluorooctanoate (PFOA) to soil, conducted in compliance with OECD guidelines and sponsored by the Association of Plastics Manufacturers in Europe.
|
— |
AR226-2694
|
DDzRxGy3YKzmkQjbwm6y8ZJMM |
56 |
|
The document outlines a study protocol by E. I. du Pont de Nemours and Company to assess the biodegradability of 8-2 telomer B alcohol (8-2 TBA) using activated sludge from wastewater treatment facilities, with degradation monitored through chemical analysis.
|
— |
AR226-2696
|
9J20oEnJYopBwvDE1aOG19xBD |
19 |
|
The document details a study conducted by DuPont on the hydrolytic stability of a perfluorinated compound as a function of pH, completed on November 24, 2003, in compliance with U.S. EPA TSCA Good Laboratory Practice Standards.
|
— |
AR226-2697
|
jyX2NL93Ld8voEM5nkZO27q2 |
35 |
|
The document discusses potential sources of perfluorinated carboxylic acids (PFCAs) in the environment, particularly focusing on emissions from fluoropolymer manufacturing and the degradation of fluorotelomer-based polymers, as presented by John Gannon from DuPont Central Research & Development during a workshop in Toronto in September 2004.
|
— |
AR226-2700
|
RjM151R8yZx3qGd4xQ1aKdejn |
20 |
|
The document details a study conducted by E.I. du Pont de Nemours and Company on the hydrolytic stability of a substance identified as H-24616, assessing its stability as a function of pH in compliance with EPA Good Laboratory Practice standards.
|
— |
AR226-2698
|
b56z9MdeL7gzDreZm0NQmoD6O |
44 |
|
The document discusses the challenges in measuring the physical and chemical properties of fluorinated compounds, particularly PFOA and PFOS, emphasizing their unpredictability and the need for careful method development in analytical chemistry.
|
— |
AR226-2701
|
JrLe2oN9ey1ZX8N5eQOjgmwz2 |
38 |
|
The document discusses the atmospheric chemistry of fluorotelomer alcohols (FTOHs) produced by DuPont, highlighting their volatility, gas-phase reaction kinetics, and oxidation products, while emphasizing the need for further research on their environmental behavior and degradation pathways.
|
— |
AR226-2702
|
MJZpOQ0EzjVvEZxO2Jxw6dKZz |
18 |
|
The document is a final report on the adsorption/desorption study of (14C)-8-2 Telomer B Alcohol conducted by Covance Laboratories for the Telomer Research Program, adhering to OECD Guideline 106 and confirming compliance with Good Laboratory Practice regulations.
|
— |
AR226-2699
|
B8m6RmbbZov7VdNraNp1bNBZj |
91 |
|
The document is a laboratory report from E. I. du Pont de Nemours and Co., Inc. detailing the acute toxicity testing of perfluorinated compounds in rats, indicating that both tested materials are extremely toxic by inhalation.
|
— |
AR226-2918
|
ykGpxxqDDKZ7Ywk72M2Q2we6r |
6 |
|
The document reports on an eye irritation study conducted by Haskell Laboratory for E. I. du Pont de Nemours and Company, which found that the test material HL 15,388 produced moderate eye irritation in unwashed eyes and mild irritation in washed eyes in rabbits.
|
— |
AR226-2919
|
qkQrbb7rJV463OjqaJ398QbQk |
12 |
|
The document is a report from Haskell Laboratory evaluating the primary dermal irritation of a test material (HL 15,388) submitted by E.I. du Pont de Nemours & Co., which was found to cause moderate skin irritation in rabbits.
|
— |
AR226-2920
|
x1drGGG393jprGonamzMmgr11 |
10 |
|
The document is a Haskell Laboratory report evaluating the dermal corrosivity of a test material (15,615) submitted by E.I. du Pont de Nemours & Co., which found that the material caused very slight or slight erythema with little or no edema in rabbits, indicating it is not corrosive to skin.
|
— |
AR226-2922
|
6b19a5rJrOwMV78GdRDJZwBVR |
10 |
|
The document reports on a study conducted by E. I. du Pont de Nemours and Co., Inc. at the Haskell Laboratory, which investigated the toxicity of aerosolized perfluorinated compounds based on particle size, finding that smaller particles (less than 3.1 um) were associated with increased mortality in rats, although the relationship was not consistent across all exposure scenarios.
|
— |
AR226-2923
|
Y9Jx3zRa4y3VKn1omgbj3LqXn |
14 |
|
The document reports on a study conducted by Haskell Laboratory for E. I. du Pont de Nemours and Co., which determined the approximate lethal concentration (ALC) of a particulate compound (not specified) to be 42 mg/m³ through inhalation in male Crl:CD rats, revealing severe pulmonary damage, while the intravenous lethal dose (ALD) was found to be 500
|
— |
AR226-2925
|
4vG3Y8ELJODqRBmgokLqOBoyN |
6 |
|
This document appears to be a research report from the Haskell Laboratory for Toxicology and Industrial Medicine detailing a study on the inhalation toxicity of various particle sizes in rats, including methodologies for exposure and observations on mortality rates.
|
— |
AR226-2924
|
Qkzv1a7m2NXJqq1ENOv3j62O5 |
12 |
|
The document is a toxicity study report by ATOCHEM on the acute toxicity of a sample (likely containing PFOA or PFOS) to Daphnia Magna, indicating a minimum concentration for 100% immobilization greater than 7 g/l and a maximum concentration for 0% immobilization of less than 0.01 g/l.
|
— |
AR226-2933
|
jmm4BG2JjDJYJ7Dar4BmQbOy5 |
6 |
|
The document reports on a study conducted by ATOCHEM to determine the bacterial growth inhibition effect of a substance on Pseudomonas putida, with results indicating varying levels of optical density at different concentrations.
|
— |
AR226-2967
|
zQYG45M5Rq7gKeNeL57MkwRxz |
4 |
|
The document reports on the acute toxicity testing of a substance (unspecified) on Daphnia magna, conducted by ATOCHEM, indicating a 24-hour and 48-hour CEm50 greater than 75 mg/l and 3.78 mg/l respectively, with a control immobilization rate of 10%.
|
— |
AR226-2972
|
ZJx9GGOBk9pgJDMeGrvyZx72Y |
7 |
|
The document reports on a static acute 96-hour toxicity test of the substance H-19913, a polymer related to perfluorinated compounds, conducted by DuPont, which found low toxicity to fathead minnows with an LC50 between 500 to 5000 mg/L.
|
— |
AR226-2981
|
Xz5J3ZDxnYeJrpr7L1YVZK1Rd |
13 |
|
The document summarizes a study conducted by DuPont on the skin irritation potential of the substance 9-19913 (a perfluorinated compound) in rabbits, which found it to be a moderate skin irritant.
|
— |
AR226-2982
|
5bJ8ZoOOm1Jkkk0V6LnaDO6NJ |
11 |
|
The document discusses a study conducted by DuPont on the acute lethal dose (ALD) of a substance referred to as H-19913, which was administered to rats via intragastric intubation, noting that diarrhea was observed at doses greater than 5000 µg/kg.
|
— |
AR226-2987
|
R3MyoEGGV516pn2OLmL0xDjv |
8 |
|
The document discusses fluorotelomers, including their manufacturing processes, applications, and environmental fate, with contributions from DuPont Chemical Solutions Enterprise.
|
— |
AR226-2703
|
jBNrkeNQVzymXzBL1RxjZmeQ2 |
23 |
|
The document discusses the hydrolytic stability and environmental degradation pathways of fluorotelomer-based polymers, specifically those produced by DuPont, concluding that these polymers are stable under various pH and temperature conditions and remain largely intact during disposal processes.
|
— |
AR226-2704
|
Yj6dadmxmZB10OM1QQJk5y21N |
24 |
|
The document reports on a study conducted by E.I. du Pont de Nemours and Company, titled "Hydrolytic Stability of H-25435 as a Function of pH," which evaluates the stability of the substance H-25435 under varying pH conditions in compliance with Good Laboratory Practice standards.
|
— |
AR226-2705
|
DD5mBdbznV7KbJG97ZDgBxGaO |
46 |
|
The document summarizes a presentation by DuPont at the 2004 ASMS Annual Meeting regarding the development of analytical methods for the quantitative determination of perfluorooctanoic acid (PFOA) extracted from textiles and carpets using LC/MS/MS techniques, highlighting the challenges posed by diverse sample compositions and the effectiveness of the extraction methods employed.
|
— |
AR226-2707
|
EdzYaKKXOzzvmeX1VXE3vmbvR |
6 |
|
The document summarizes presentations by DuPont at the Society of Environmental Toxicology & Chemistry conference regarding the biotransformation of fluorotelomer substances, specifically 8-2 Telomer B alcohol, by microorganisms and the environmental fate of fluorinated substances, highlighting their biodegradation potential and transformation pathways.
|
— |
AR226-2706
|
DMr08Mr36xYomjKw8zYoKvaQ5 |
13 |
|
The document summarizes a study conducted by DuPont on the biodegradation potential of 14C-labeled 8-2 Telomer B Alcohol, a fluorinated compound, using acclimated bacterial cultures to investigate its metabolic pathways and transformation products.
|
— |
AR226-2708
|
gDegDRk9q3ONRQkNN43j5MN9e |
3 |
|
The document summarizes presentations by DuPont at the American Chemical Society meetings, specifically focusing on the extraction of perfluorooctanoic acid (PFOA) from polytetrafluoroethylene polymers and related measurements involving fluorinated compounds.
|
— |
AR226-2709
|
JvEGB2ww1QxK5xxxJm9o8YdoK |
2 |
|
The document discusses the observed mammalian and environmental metabolites of the telomer compound 8-2 alcohol, noting specific perfluorinated metabolites such as F(CF2)8COOH and F(CF2)7COOH, while indicating that metabolites with less than an 8-carbon chain have not yet been investigated.
|
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AR226-2711
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44Jq5x0O5GEz1OaXa1oxkab3V |
2 |
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This study by DuPont researchers investigated the aerobic biodegradation of 14C-labeled 8-2 Telomer B Alcohol in activated sludge, identifying several biotransformation products including PFOA, which represented 2.1% of the initial mass after 28 days.
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AR226-2710
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5xMY2V9QN70kLvZJYY9LG3jJ |
29 |
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The document critiques the findings of Ellis et al. regarding the thermal degradation of polytetrafluoroethylene (PTFE), arguing that their methodology failed to accurately capture degradation products such as carbonyl fluoride and trifluoroacetic acid (TFA), which raises doubts about their conclusions on the environmental impact of fluorinated compounds.
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AR226-2712
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jBGa6LpLgDrz0rNRp08Qpvx3O |
2 |
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The document discusses the construction of a human physiologically based pharmacokinetic (PBPK) model for perfluorooctanoic acid (PFOA), highlighting the significance of inhalation and oral exposure studies, and the complexities in understanding elimination mechanisms in humans compared to animal models.
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AR226-2714
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emrw3pJoDr3z7rdE1GBbBGr19 |
3 |
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This document presents preliminary analytical results from DuPont's Occupational Blood Monitoring Program for PFOA, detailing serum sample concentrations and recovery rates, with final results pending.
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AR226-2715
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MJ55XOrZqaaBaObyRBk09EVBy |
4 |
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The document outlines a study protocol prepared for DuPont Haskell Laboratory to conduct cross-sectional surveillance on the health status of a community sample in relation to serum biomarker exposure to ammonium perfluorooctanoate (PFOA).
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AR226-2716
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M4zpXVnNZVQyJQaOekNek3k7 |
67 |
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The document is a final report detailing laboratory-scale thermal degradation studies of fluorocarbon materials, specifically focusing on perfluorooctanoic acid (PFOA), conducted by the University of Dayton Research Institute for DuPont Chemical Solutions Enterprise.
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AR226-2713
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1QQxB739MDygJJbDabGRe0Odq |
116 |
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The document reports a biodegradability study conducted by ELF ATOCHEM on a substance, which demonstrated 100% biodegradation within 5 days, indicating that the substance is easily biodegradable according to OECD guidelines.
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AR226-2999
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3JmrVzjbvJ6M7OB6Ne31a948x |
28 |