CD 14 — AR226-1068a

EPA administrative record segment: CD-14--AR226-1068a (1,777 documents).

Page 9 of 18 — 1,777 documents
Title / Summary Year AR226 Docket Hash ID Pages
The document is a final report on a mutagenicity test of a substance identified as T-6357, conducted by Corning Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to assess potential genetic toxicity. 1996 AR226-0233 zn7rzZkGaQgDV8rLBvo4Qyp0 27
The document is a final report of a mutagenicity test on T-6294 conducted by Corning Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance. 1996 AR226-0239 7ORDyg4OaV8nn6NdbeLMerRoe 36
The document is a final report of a mutagenicity test on PFOA conducted by Corning Hazleton Inc. for 3M, detailing compliance with Good Laboratory Practice regulations and quality assurance inspections. 1996 AR226-0252 Nez6m3xmkpNOnrkLnvaD3Q5ow 37
The document is a final report of a mutagenicity test on T-6295 conducted by Coming Hazleton Inc. for 3M, using an in vivo mouse micronucleus assay to evaluate the potential mutagenic effects of the substance. 1996 AR226-0130 a5bwq1ErY2az1OJ0m3O1aZQX 39
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by Pace Analytical Services for 3M Company, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks detailed methodology and characterization of the sample. 1996 AR226-0692 qkRmdRJp0DrR4gpGd2EyBrBdK 7
The document is a final report from Hita Research Laboratories on a bacterial reverse mutation test of a substance referred to as T-1, sponsored by Sumitomo 3M Limited, conducted in compliance with Japanese toxicity investigation standards. 1996 AR226-0136 4aEJgykrQLBD4k4ZG8x69m3NQ 29
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacks reliable conclusions due to insufficient method description and characterization of the inoculum. 1996 AR226-0848 dQ3me8JQemE30JO7x8k7XL7Zb 9
The document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on juvenile golden orfe fish, revealing a 96-hour LC50 value of 58 mL/L. 1996 AR226-0849 qdy4j0aBV3g3oqLO3892z4OJM 10
The document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) tested on Daphnia magna, revealing a 24-hour EC50 value of 64 mL/L for the mixture. 1996 AR226-0851 YDRyLJYyx3wgpgdLwwkKJM23D 10
The document reports on a TTC test conducted by 3M Company on a mixture containing 1.30% PFOS, indicating that exposure concentrations between 0.1 and 10 mL/L showed results comparable to the blank control, but the study lacks detailed descriptions and data quality is rated as Klimisch ranking 3. 1996 AR226-0852 Rjw5MwKD0b5262X9jajMrmRX 10
The document reports on an Activated Sludge Respiration Inhibition Test (MITI Test) conducted on a mixture containing 1.30% PFOS, revealing a 28-day biological oxygen demand of 82.5%. 1996 AR226-0853 RaMaw1RRvrnL0jaxmBNgNy4mE 10
The document details a Microbics Microtox toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) as part of the test substance FC-603EF, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized concentrations of impurities. 1996 AR226-0854 Mob49Qak54V8GjoX55VMxDDxz 9
The document describes an activated sludge respiration inhibition test conducted on a mixture containing 1.30% PFOS, assessing its acute toxicity using OECD Guideline 209, with results indicating potential inaccuracies due to the presence of impurities. 1996 AR226-0855 gNNpzOLkOey1zN3O6w5229DJ 10
This document details an acute toxicity test of a PFOS-containing mixture (FC-603EF) on Daphnia magna, conducted under OECD Guideline 202, with findings indicating the need for careful interpretation due to the presence of impurities in the test sample. 1996 AR226-0856 RqBaBOj9Mgp12gKDepMxEOvV 10
The document details a toxicity test conducted on a mixture containing 1.30% perfluorooctanesulfonate (PFOS) using the OECD Guideline 201 method to assess its impact on the growth of the aquatic plant species Selenastrum capricornutum over a 96-hour exposure period. 1996 AR226-0857 2jQyZbpKZzG19x8ye6KoZpMa6 12
The document is a quality assurance statement for a chromosomal aberration study of Sample D-1 conducted by Mitsubishi Chemical Safety Institute Ltd. for Sumitomo 3M Limited, adhering to GLP standards. 1996 AR226-0308 06Ew28g9dka4JrGrevxLOEnQx 17
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M Company, indicating high Chemical Oxygen Demand (COD) values but noting that the sample's purity was not properly characterized, which may affect the accuracy of the biodegradation potential assessment. 1996 AR226-0890 v6LDZjxzVpKdQ6momeD2Yeqrb 6
The document reports on a toxicity test of a PFOS-containing mixture (FC-3017) on the aquatic plant species Selenastrum capricornutum, indicating that the study followed OECD guidelines but lacked detailed data on the toxicity results due to incomplete characterization of the test substance. 1996 AR226-0895 n9VkrjOqa2qmBj28wvYpJJGp1 7
This analytical report by Advanced Bioanalytical Services investigates the in vitro metabolism of compounds T-6292, T-6293, T-6294, and T-6295 using rat and human hepatocytes with advanced LC/MS techniques, prepared for the 3M Medical Department. 1996 AR226-0328 0qzOEwo74V77Kd4kqgw23LJZO 45
The document reports on a study of 51 employees with the highest blood levels of C-8 (perfluorooctanoic acid), indicating minimal evidence of disease attributable to C-8, with some elevations in liver enzymes and a few cases of kidney disease, but no definitive conclusions due to lack of controlled studies. 1996 AR226-1307 jyvkNYO19w9nq8qn87EMMQ2B2 6
The document is a final report on a mutagenicity test of T-6564 conducted by Coming Hazleton Inc. for 3M Corporation, using an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance. 1996 AR226-0430 By070g964dLojDb7rvqJ5rggj 26
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosomal aberrations in Chinese hamster ovary (CHO) cells using the substance T-6564, with findings compliant with Good Laboratory Practice regulations. 1996 AR226-0431 x5bLLy8ROq22yo142VX4LxGeb 30
The document is a final report of a mutagenicity test conducted by Coming Hazleton Inc. for 3M Corporation, assessing the mutagenic potential of a substance identified as T-6564 using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay, with findings indicating compliance with Good Laboratory Practice regulations. 1996 AR226-0432 kVOdo9mBNQdJrGNnoR1Q2x7J 34
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, measuring chromosome aberrations in human whole blood lymphocytes related to the substance T-6342. 1996 AR226-0433 MoGE6nEoexgJEVzr7g3kezZ4k 29
The document is a final report on a mutagenicity test conducted by Corning Hazleton for 3M Corporation, assessing chromosomal aberrations in Chinese hamster ovary (CHO) cells related to the substance T-6342. 1996 AR226-0434 kmBvpgbYdkb0LbLwox5yN9nDb 35
This letter from the Robert A. Taft Laboratories addresses a Health Hazard Evaluation regarding employee exposure to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) at the 3M Corporation in Cottage Grove, Minnesota, noting that no health effects were observed despite concerns over elevated blood fluoride levels and the implementation of engineering controls and personal 1996 AR226-1350 G639E4gvM3ByqzdxGqQxomY6q 6
The document discusses a study by Gilliland and Mandel published in the American Journal of Industrial Medicine, which evaluates the effects of serum perfluorooctanoic acid (PFOA) on hepatic enzymes, lipoproteins, and cholesterol in 115 occupationally exposed workers, finding no significant clinical hepatic toxicity at the measured PFOA levels, although it suggests PFOA may exacerbate obesity 1996 AR226-0475 YKrppk55rVoVDJGN8d1Jve80 8
The document reports the results of a Microbios Microtox toxicity test conducted on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating that the 30-minute EC50 value was 730 mg/L, suggesting low acute toxicity to the test organism Photobacterium phosphoreum. 1996 AR226-0521 LpOZobN0vED3BQ4q5gYbEbxqz 6
The document reports the results of a Microbios Microtox toxicity test on perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating an EC50 value of 4460 mg/L at 5 minutes and 3360 mg/L at 15 minutes, although the test sample's purity was not sufficiently characterized. 1996 AR226-0522 VG1mbwXZeOgJwgzJxYBqyZ5mN 8
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically the test sample FC-1015-X, to evaluate its toxicity using Photobacterium phosphoreum, although the purity of the sample was not sufficiently characterized. 1996 AR226-0523 zzqo96p9wBqkzye1Y6Z94za30 6
The document describes an activated sludge respiration inhibition test conducted on perfluorooctanoic acid (PFOA) ammonium salt, specifically the FC-1015-X sample, to assess its toxicity compared to a reference substance, 3,5-dichlorophenol, using activated sludge from a wastewater treatment plant. 1996 AR226-0524 GmOYDNaxqnEvpgbm8pmOQ6NQm 9
The document reports on a toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically examining its effects on the aquatic plant species Selenastrum capricornutum using a mixture from the 3M product FC-1015, with findings indicating potential toxicity but noting that the purity and characterization of the test sample were incomplete. 1996 AR226-0526 Yj4oEGwoD2YQVp43wJV4J4e2E 23
The document details an acute toxicity test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), specifically the FC-1015 sample, on Daphnia magna, conducted under USEPA guidelines, with findings indicating that the toxicity data may not accurately reflect the test substance due to impurities in the sample. 1996 AR226-0527 EvbvnxwZxmKy8DKwDg7R82wzx 28
The document details an acute toxicity test of perfluorooctylsulfonate (PFOS) conducted on the fish species Pimephales promelas, using a test sample from 3M, with specific conditions and methods outlined for the 96-hour exposure period. 1996 AR226-0534 oDbVjVDG5NOVa89JXMVrykx5X 11
The document details an acute toxicity test of perfluorooctylsulfonate (PFOS) on the aquatic invertebrate Daphnia magna, conducted by 3M in 1996, using a mixture of the test substance in water, with monitoring of various environmental parameters. 1996 AR226-0535 gEgVDwdDjo010Q4GDQyoJxDRQ 11
The document details a Microtox toxicity test conducted on a mixture containing perfluorooctylsulfonate (CAS # 251099-16-8) produced by 3M, indicating that the test sample was a 2-phase dispersion and involved Vibrio fischeri as the test organism, although no adjustments were made for the actual concentration of the test substance. 1996 AR226-0538 KG3DQD4NKXBXdBqK8p2KxNmex 7
The document discusses a meeting scheduled for December 6, 1996, involving Rik Brandenburg and representatives from Hoechst and ICI to collaborate on analytical methods for determining the migration of C-8 (PFOA) from PTFE-coated pans into food simulants, addressing challenges in measuring migration into olive oil. 1996 AR226-1665 71wwRM6O7EGoD75eV5Eomdba8 1
The document reports on a biodegradation test for a mixture containing perfluorooctanesulfonate (PFOS) conducted by MDS Environmental Services for 3M Canada, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking conclusive results due to insufficient characterization of the sample and methodology. 1995 AR226-0691 qdapL4BLeep4rdYy09nyXwEKk 3
This document details an acute toxicity test of a PFOS-containing mixture (FC-201AF) on fathead minnows (Pimephales promelas) conducted according to OECD Guideline 203, with findings indicating the need for caution due to the presence of impurities in the test sample. 1995 AR226-0693 vVzJ1pjrBJDy8voz769qrvxq8 7
The document details a toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the freshwater algae species Selenastrum capricomutum, following OECD guidelines, although the study's results and specific conditions are inadequately characterized. 1995 AR226-0694 X71yvpzXKzOdDk814rXaJj4B 6
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on the aquatic invertebrate Daphnia magna, indicating that the test sample, FC-201AF, includes 3% PFOS among other components, but notes that the data may not accurately reflect the toxicity of the fluorochemical due to incomplete characterization of impurities. 1995 AR226-0698 4abOMo0E8zvpy6a8rNz2ajJrV 3
The document reports on a Microbios Microtox toxicity test conducted on a mixture containing 3% PFOS, revealing a 5-minute EC50 value of 154 mg/L for the test organism Photobacterium phosphoreum. 1995 AR226-0699 v61JKKRBnpLaV5kY8JqKvVZjq 7
The document describes an Activated Sludge Respiration Inhibition Test conducted on a mixture containing 3% perfluorooctanesulfonate (PFOS) and various other components, indicating that the data may not accurately reflect the toxicity of the fluorochemical due to incompletely characterized concentrations of impurities. 1995 AR226-0700 O6rx0VMMrmJVabp57aaZNJ3X 10
The document outlines a study conducted by 3M Medical Department Toxicology Services to determine the metabolism of test articles T-6292, T-6293, T-6294, and T-6295 using isolated rat and human hepatocytes, with the aim of generating data for regulatory applications related to FDA permits. 1995 AR226-0162 1Q98BpDOEw1Y238E889MZjrxa 10
The document details a nitrification inhibition test conducted on a mixture containing perfluorooctanesulfonate (PFOS) and other components, indicating that the test was performed using activated sludge from a wastewater treatment plant to assess the impact of PFOS on microbial nitrification. 1995 AR226-0765 bBqgb20qEdvbDBVvDVJ41rk13 8
The document reports on a nitrification inhibition test conducted on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the EC50 for the test substance was greater than 498 mg/L, suggesting low toxicity to nitrifying microorganisms. 1995 AR226-0766 rpdXG9GRmjB6YKwXekRZea6vG 6
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1% PFOS, revealing that the test was performed under standard guidelines without GLP compliance, and highlights the test conditions and methodology used to determine toxicity levels. 1995 AR226-0767 zQzwE6L3YOgQ3kwBxNkbGzYQm 9
The document reports on a blood testing program conducted in June 1995 at the Antwerp plant to measure individual exposures to PFOS and PFOA, comparing exposure levels among participants and with other fluorochemical manufacturing facilities while analyzing various health parameters. 1995 AR226-0175 reJ21b8KegmwnrapG0BgNb2oG 15
The document details a toxicity study of a mixture containing 0.5% PFOS, conducted according to OECD guidelines, assessing its effects on the growth of the freshwater algae species Selenastrum capricomutum over a 96-hour exposure period. 1995 AR226-0864 bBG253KR2KBRzeZ27gzxk6x7y 6
The document details a Microbios Microtox toxicity test conducted on a mixture containing 0.67% PFOS, identifying its composition and noting that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities. 1995 AR226-0891 3eBbq80BaQ68Nkx9bvd03Qm3J 12
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.67% perfluorooctanesulfonate (PFOS) as part of the test substance FC-3017, with exposure concentrations ranging from 1.0 to 1000 mg/L over a 96-hour period. 1995 AR226-0892 10Nv7k4Y6KxapzygqemQDQxBq 7
The document details an activated sludge respiration inhibition test conducted on a mixture containing perfluorooctanesulfonate (PFOS) as part of FC-3017, indicating that the test was performed to evaluate the toxicity of the fluorochemical component using OECD Guideline 209. 1995 AR226-0893 ZnonYZd2jgEbnLr89mYgJ4Dx0 10
This document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, using a sample produced by 3M in Antwerp, Belgium, and outlines the test conditions and methodology according to OECD Guideline 202. 1995 AR226-0894 3QnQZwd7qJQv1knL6pmr9g3BD 9
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas) according to OECD Guideline 203, with details on the test conditions and methodology used to determine toxicity. 1995 AR226-0905 dDx4Lr9VMo8bpVbpRZEpBJoKQ 11
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on Daphnia magna, conducted under OECD guidelines, with specific conditions and concentrations outlined, although the results are not statistically applicable due to the nature of the study. 1995 AR226-0906 kDG023p7vgeyzB8wVdakavrzD 3
The document details a Microbios Microtox toxicity test conducted on a mixture containing Perfluorooctanesulfonate (PFOS) to assess its acute toxicity using the Photobacterium phosphoreum species, with results indicating various nominal concentrations for evaluation. 1995 AR226-0907 REdaNNQ0adnnM4wrYpev2Gwz 13
The document details an Activated Sludge Respiration Inhibition Test conducted on a mixture containing Perfluorooctanesulfonate (PFOS) to assess its impact on respiration rates in activated sludge, using a method based on OECD Guideline 209. 1995 AR226-0908 ZBEKQw3nqV9n8dvJBovMKq4aL 10
The document details the ion spray LC/MS determination of perfluoro analytical standards provided by 3M Medical Department, prepared by Advanced BioAnalytical Services, Inc. for toxicology studies. 1995 AR226-0330 VJvYGBv76oNm7am6xE6njBYmw 60
The document reports on a biodegradation study of the perfluorinated compound 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (CAS # 423-825), indicating low biodegradability results of 4%, 1%, and 6% across three replicates, while raising concerns about the purity and methodology used in the testing process 1995 AR226-0412 bmjxxok3GJQxN5Y7yZMvJ4QD 35
The document is a final report on an acute dermal toxicity study of T-6342, sponsored by 3M and conducted by Corning Hazleton Inc. in accordance with OECD guidelines, completed on October 24, 1995. 1995 AR226-0427 85Xp870vvx96Ee2QRnr3p8z1a 32
The document is a final report on a mutagenicity test of T-6342 conducted by Corning Hazleton for 3M Corporation, which involved an in vivo mouse micronucleus assay to assess the potential mutagenic effects of the substance. 1995 AR226-0435 a4pma8knD6mxoENYBELXYZYBX 23
The document is a final report on a mutagenicity test of a substance identified as T-6342 conducted by Corning Hazleton for 3M Corporation, using the Salmonella - Escherichia coli/mammalian-microsome reverse mutation assay, confirming compliance with Good Laboratory Practice regulations. 1995 AR226-0436 mBNDgBng77m1gnvn7VEmnzgO 30
The document details a bioconcentration test of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted on fathead minnows to analyze fluoride levels, using a method developed by 3M, although the purity of the test sample was not fully characterized. 1995 AR226-0496 91BZ4xLpGkGvBbznqEM77vBEe 24
The document details a toxicity study on Perfluorooctanoic acid (PFOA) conducted in 1995, assessing its effects on the aquatic plant species Selenastrum capricornutum using U.S. EPA guidelines, with findings reported in 1996. 1995 AR226-0518 JJKbkBe6K3dKnYEYo3wDErewr 28
The document details an acute toxicity study of Perfluorooctanoic acid (PFOA) conducted in 1995-1996 on the fish species Pimephales promelas, using a test substance with a purity of 96.5-100% PFOA, to determine its lethal concentration (LC50) under controlled laboratory conditions. 1995 AR226-0519 rQrorpMbYD24bEq23dvKVvM7 29
The document details a study on the acute toxicity of Perfluorooctanoic acid (PFOA) to the aquatic invertebrate Daphnia magna, conducted under U.S. EPA-TSCA guidelines, with a focus on determining LC50 and EC50 values over a 48-hour exposure period. 1995 AR226-0520 qdJQKyOa0NDzEKXQNKQZ8gXEK 29
The document is a final report on the analysis of T-5877 in a cell proliferation assay conducted on rat liver cells, submitted to 3M Corporation by Hazleton Washington, Inc., confirming compliance with Good Laboratory Practice regulations and the integrity of the study results. 1994 AR226-0270 LgbBKxNQDyOQqmXM5Mqp3n3xQ 53
The document reports on a failed biodegradation study of Perfluorooctanesulfonate, Lithium salt (PFOS Li salt), conducted by Pace Laboratories for 3M Company, which could not produce usable carbonaceous BOD data after multiple attempts due to potential toxicity or lack of demand from the sample. 1994 AR226-0058 M23BRMgddR7o5rX77rr9Mzna 4
The document details an acute toxicity test conducted on fish (Pimephales promelas) using a test sample of Perfluorooctanesulfonate, Lithium salt (PFOS Li salt) from a 3M production lot, with a focus on determining the LC50 values over a 96-hour exposure period. 1994 AR226-0111 4aw1B0nvDmdEDOaJNkmYODV1R 9
The document reports on an acute toxicity study of Perfluorooctanesulfonate (PFOS Li salt) on the aquatic invertebrate Daphnia magna, finding a 48-hour EC50 value of 210 mg/L. 1994 AR226-0112 g2Qdx4NjKqoNpnbLgXoM2g4Z3 7
The document reports the results of a Microtox toxicity test conducted on a mixture of perfluorooctanesulfonate lithium salt (PFOS Li salt) in water, indicating an EC10 value of 564 mg/L and an EC50 value greater than 1000 mg/L for Photobacterium phosphoreum after 15 minutes of exposure. 1994 AR226-0113 aJXdrMgXN0G557NrE41nZvyrN 12
The document details an Activated Sludge Respiration Inhibition Test conducted on Perfluorooctanesulfonate, Lithium salt (PFOS Li salt), indicating that the test solutions exhibited low dissolved oxygen levels during the experiment, which may have affected the results. 1994 AR226-0114 VjOaMroed3Jqny9BnyLDOY13w 12
This document reports on a biodegradation study of a mixture containing 0.5% perfluorooctanesulfonate (PFOS) conducted by Pace, Inc. for 3M Company, highlighting significant Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values while noting the study's lack of methodological clarity and sample purity characterization. 1994 AR226-0862 MEkKnOe22eMJ4B6e3vpovRa9 6
The document reports on an acute toxicity test of a mixture containing 0.5% PFOS, conducted on fathead minnows (Pimephales promelas) using OECD Guideline 203, with results indicating the need for caution due to the presence of impurities in the test sample. 1994 AR226-0863 OzbNJ0g4ypDLon1myMEQME6Nv 6
The document reports on an acute toxicity test of a mixture containing 0.5% PFOS (perfluorooctanesulfonate) conducted on Daphnia magna, detailing the test conditions and methodology used in the study. 1994 AR226-0865 KzXQgRMN6KyQap4QoNLwnGxx6 4
The document details a Microtox toxicity test conducted on a mixture containing 0.5% perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the test sample, FC603F, may have incompletely characterized concentrations of impurities affecting the toxicity data. 1994 AR226-0866 1bYxYMO4J72eY41jNbwxMDMK 13
The document details an activated sludge respiration inhibition test conducted on a mixture containing 0.5% PFOS, produced by 3M, to evaluate its toxicity using OECD Guideline 209, with results indicating potential inaccuracies due to impurities in the test sample. 1994 AR226-0867 5OdLLoJZXpBQ50wDda8JynVz 10
The document reports on the evaluation of the mutagenic activity of T-5874 using the Ames Salmonella/microsome test, conducted by NOTOX B.V. in compliance with GLP standards. 1994 AR226-0297 Lg6zw7e1VqeD1pw2pQRwe5D8w 24
The document reports on a study conducted by NOTOX evaluating the ability of the substance T-5874 to induce chromosome aberrations in cultured peripheral human lymphocytes, adhering to Good Laboratory Practice standards. 1994 AR226-0298 jB05LEY5aJye6eap5qeL5wwBy 27
The document reports on the evaluation of the mutagenic activity of T-5874 in an in vitro mammalian cell gene mutation test using L5178Y mouse lymphoma cells, conducted by NOTOX in compliance with GLP standards. 1994 AR226-0299 M497bJOOEZ674aKQrvXQmwQDy 23
The document is a final report on the analysis of T-5794 in a cell proliferation assay using rat liver cells, conducted by Hazleton Washington, Inc. for 3M Corporation, confirming compliance with Good Laboratory Practice regulations. 1994 AR226-0302 JKnB4r6bwb618LRmp9wN4Xae 37
The document is a final report on the analysis of T-5878 in a cell proliferation assay using rat liver cells, conducted by Hazleton Washington, Inc. for 3M Corporation, with findings compliant with Good Laboratory Practice regulations. 1994 AR226-0303 2jDEEdYDRzJGOJvj7nGo5RxL5 50
The document reports on a study conducted by NOTOX B.V. to evaluate the ability of the substance T-5869, sponsored by 3M Belgium, to induce chromosome aberrations in cultured peripheral human lymphocytes, adhering to Good Laboratory Practice standards. 1994 AR226-0318 8OzzNqVyO2exLrB90BOjDGQrK 26
The document reports on a fluorochemical exposure assessment of 3M Decatur chemical and film plant employees, revealing a geometric mean serum PFOS level of 0.944 ppm among chemical plant workers and 0.136 ppm among film plant workers, with the highest PFOS level recorded at 10.600 ppm, and indicates that the findings will inform an updated retrospective cohort mortality study. 1994 AR226-0950 LJNoymdpvkML70m0nNq7ovq2z 406
This document reports the results of a study conducted by 3M Company to estimate the log Pow (partition coefficient) for N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol), finding values of 5.6 and 4.4 for different peaks. 1994 AR226-0379 RYxz7dw3x4V28drMZDM22rbk 17
The document reports on the physical and chemical properties of the perfluorinated compound 2-(N-Ethylperfluorooctanesulfonamido)ethyl acrylate (also known as D-1), indicating a water solubility of 0.89 mg/L and varying hydrolysis rates at different pH levels, while noting that the purity and identity of the substance 1994 AR226-0973 X8rY0jBgBg5EX37m903nezjOx 63
This is a research article discussing the prevention of fluvastatin-induced toxicity, mortality, and cardiac myopathy in pregnant rats through mevalonic acid supplementation, highlighting significant adverse effects observed at certain dosages of fluvastatin. 1994 AR226-0559 3eBvjeeL1wp2qB3mneoqm7BdJ 8
This letter from DuPont to First Brands discusses the potential risks associated with using Teflon K-20, which contains <0.2% ammonium perfluorooctanoate (APFO), as a dedusting agent in cat litter, highlighting the need to consider the safety of employees, cats, and cat owners. 1994 AR226-1662 3eLXjDG4BaL9gywQJB916bZOE 3
The memorandum discusses the interest in incorporating micro powders into shaving gel products, specifically addressing concerns about the elimination rate of C-8 (likely referring to PFOA) from the body and the feasibility of this approach. 1994 AR226-1663 3JwXxvdrpxzjoMBMDLYEzZGZ0 2
This document outlines a method developed by 3M for the determination of N-Ethyl Perfluorooctanesulfonamide in air using silica gel sampling tubes and gas chromatography. 1993 AR226-0241 4v0EOp706b1MwJZdVzrNJe3Ra 2
The document is a final report on a mutagenicity test for T-5710 conducted in an in vivo rat micronucleus assay, submitted to 3M Corporation by Hazleton Washington, Inc., indicating compliance with EPA FIFRA Good Laboratory Practice Standards. 1993 AR226-0250 44rVzK37VeGV037B6MYG5n7gG 26
The document is a final report on a genotoxicity test of T-5710.1, conducted by Hazleton Washington, Inc. for 3M Corporation, which assessed unscheduled DNA synthesis and cell proliferation in rat liver cells, ensuring compliance with Good Laboratory Practice regulations. 1993 AR226-0251 Vjre9oGL853k0RzkEOaNdKGZN 32
The document outlines a research protocol by 3M to analyze inpatient and outpatient claims data from Decatur chemical and film plant employees between 1993 and 1998, aiming to compare observed claims events to expected numbers while accounting for age and gender, with a focus on the potential health impacts of exposure to perfluorinated compounds. 1993 AR226-0022 om8ZzDKbZymZ6ZkZgOv1n0oY8 19
The document presents a biodegradation study of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient characterization of the sample and methodology. 1993 AR226-0701 6bdw5yKJ8beJOxnY5zbkVJbEg 13
The document reports on a microbial inhibition test evaluating the dehydrogenase activity of a mixture containing 3.0% PFOS (perfluorooctanesulfonate) produced by 3M Company, indicating that the test results are inconclusive due to incomplete characterization of the sample and lack of detailed methodology. 1993 AR226-0705 evEJmK0NVrgjg4dwV7N46maXe 14
The document reports on an acute toxicity test conducted on fish using a mixture containing 3.0% PFOS (perfluorooctanesulfonate) as part of the test substance FC-201F, with a 48-hour no observed effect concentration (NOEC) determined to be 500 ppm. 1993 AR226-0706 evNyYGGgm17NExwYb7zVNweBp 14
The document reports on a toxicity test of a mixture containing 1.30% PFOS, conducted on the aquatic plant species Scenedesmus subspicatus, revealing a 72-hour EC50 value of 65 mL/L based on nominal concentrations. 1993 AR226-0850 gDEb7BN33joRBN2oxbNbRjqba 10
The document is a final report on a mutagenicity test of T-5711 conducted by Hazleton Washington, Inc. for 3M Corporation, using an in vivo rat micronucleus assay to comply with U.S. EPA FIFRA guidelines. 1993 AR226-0296 EmqLyBd46N6N7rRmb5r9OYV1L 41
The document is a final report on a genotoxicity test of T-5711.1 conducted by Hazleton Washington, Inc. for 3M Corporation, which involved in vivo/in vitro assays in rat liver cells to assess DNA synthesis and cell proliferation. 1993 AR226-0295 8VOyXR5VBgdzd6vexJx0oGDLm 46
The document details a manometric respirometry test conducted in 1993 to assess the biodegradability of a mixture containing 6% PFOS, indicating that the data may not accurately reflect the biodegradability of the fluorochemical component due to incompletely characterized concentrations of impurities. 1993 AR226-0899 nmg59Qd99z54bbJoro5VXMY6G 10