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This document is a supplemental submission to the EPA regarding a toxicology study conducted by 3M on dermal contact absorption of PFOS (perfluorooctanesulfonate) and other perfluorinated compounds in rats, indicating that these compounds were found in liver and serum samples after exposure to certain carpet and upholstery protector products that 3M has phased out.
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2004 |
AR226-1874
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peG39Q9DkqVJyw1KmDYQ15o2B |
1 |
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The document is a final report on a 28-day repeated dermal contact study of PFOS conducted by Fraunhofer ITEM on Sprague-Dawley rats, sponsored by 3M, detailing the study's methodology, results, and findings related to the concentration of PFOS in liver and blood serum samples.
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AR226-1874
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9Jq5Jg17gq6DkyyMmjgO4Nbx3 |
25 |
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The document is a final report from Fraunhofer ITEM detailing a 28-day repeated dermal contact study of 3M test articles in Sprague-Dawley rats, focusing on the analysis of fluorochemical residuals, specifically N-Methyl FOSE and N-Methyl FOS Amide concentrations in various treated products.
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AR226-1874
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oeqGGkmnqNRo06449M89m0p7g |
56 |
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The document presents findings from a 28-day repeated dermal contact study of PFOS in Sprague-Dawley rats, indicating various levels of PFOS detected in liver samples from different test articles produced by 3M, with most results showing concentrations below 0.01 ppm.
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AR226-1874
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5Dbp1aeLGj6JD3joMy97m4MX8 |
4 |
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The document presents histopathological findings from a 28-day repeated dermal contact study of 3M test articles in Sprague-Dawley rats, noting various skin and heart lesions associated with the treatments.
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AR226-1874
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gDEwr0JdN77g2v4QyaYeZBjDQ |
68 |
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The document details amendments and deviations from a 28-day repeated dermal contact study of 3M test articles in Sprague-Dawley rats, specifically addressing the pre-conditioning of fabrics with deionized water and the analysis of PFOS, PFHS, and M570 in blood samples due to the presence of PFOS in liver samples.
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AR226-1874
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kmv4RKR1vyOx35qQxvXDbmymn |
12 |
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The document presents findings from a 28-day repeated dermal contact study of 3M test articles in Sprague-Dawley rats, specifically detailing the residues of PFOS detected in rat blood serum samples on days 4 and 14.
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AR226-1874
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3QV4J953jb5xpNbmVVwan95z0 |
13 |