|
The document summarizes a study conducted for the German Government Agency for Military Technology and Procurement, which evaluated the environmental properties of fire extinguishing foam compounds, specifically a mixture containing 0.67% PFOS from 3M's FC-206, alongside various toxicity and chemical analyses.
|
1977 |
AR226-0793
|
rBZoz1QdBZL3qn7ezDpaLX6jr |
28 |
|
This document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, indicating that the test sample FC-600 consists of 1.0% PFOS and various other components, with results to be determined from the exposure conditions.
|
1977 |
AR226-0828
|
Y9KY0yBjxwEqNq4yyXw86YMy |
5 |
|
This document reports on an acute toxicity study of a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, using a sample identified as FC-600, which was treated in a SCAS reactor, with the study indicating potential toxicity but noting that data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1977 |
AR226-0829
|
gb6BzqQ0mypb0XVqGLbE8wj5V |
4 |
|
This document details an acute toxicity study on a mixture containing perfluorooctanesulfonate (PFOS) conducted on Daphnia magna, using a sample identified as FC-600, which is composed of 1.0% PFOS and various other components, to assess its effects after treatment in a SCAS reactor.
|
1977 |
AR226-0830
|
zzJqk93vDNpY0w92bgKM13rbR |
4 |
|
The document summarizes a study conducted for the German Government Agency for Military Technology and Procurement, which evaluated the environmental properties and toxicity of a fire extinguishing foam containing 0.67% PFOS (perfluorooctanesulfonate) from 3M's FC-3017, alongside other components, using various toxicity tests.
|
1977 |
AR226-0896
|
bBjJBxraK3DMw3xOmzpNYm29k |
28 |
|
The document reports on biodegradation testing of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating high Chemical Oxygen Demand (COD) values but lacking reliable conclusions due to insufficient method description and sample characterization.
|
1976 |
AR226-0777
|
zb5wXYOwgQ0Dxk2ddeVdkN4k0 |
4 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating that the test sample was a mixture with 0.67% PFOS and various other components, although the method and specific toxicity results are not provided.
|
1976 |
AR226-0789
|
QXDjKJQmVbQNrXNkRkey7xYjo |
3 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.67% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating potential toxicity but noting that data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1976 |
AR226-0790
|
zdV0ZJKL8Vd27dm4BZLydJ8V3 |
5 |
|
The document summarizes acute toxicity studies on a mixture containing 0.96% PFOS (perfluorooctanesulfonate) from 3M's production lot 2, specifically examining its effects on juvenile fathead minnows (Pimephales promelas) over a 96-hour exposure period.
|
1976 |
AR226-0897
|
2qGxmYJE9dJR9ODoXmG47MV0L |
6 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high Chemical Oxygen Demand (COD) and varying Biochemical Oxygen Demand (BOD) results, but lacks sufficient characterization of the test substance and methodology.
|
1975 |
AR226-0689
|
jmyNeRbMLM7dqVekywxgY5bG9 |
4 |
|
The document reports on an acute toxicity test of a mixture containing 6% PFOS, conducted on juvenile Pimephales promelas, indicating that the test sample's purity was not sufficiently characterized and may not accurately reflect the toxicity of the fluorochemical component.
|
1975 |
AR226-0690
|
LoB8LgRn7n6xjRmQqVQ7mLEVX |
7 |
|
The document presents a biodegradation test report for a mixture containing 1.34% perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1975, highlighting high levels of Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) but lacking detailed methodology and characterization of the test substance.
|
1975 |
AR226-0736
|
RaZMb4q4nRamo5kgXwjROgmX8 |
5 |
|
This document reports on an acute toxicity test conducted in 1975 using a mixture containing 1.34% PFOS (perfluorooctanesulfonate) on juvenile Pimephales promelas, noting that the test conditions and methods were not fully characterized.
|
1975 |
AR226-0740
|
6d392Gy2VREE23a9xvKZLZam |
3 |
|
The document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating high Chemical Oxygen Demand (COD) values but low Biochemical Oxygen Demand (BOD) results, with the study being deemed unreliable due to premature termination and lack of method details.
|
1975 |
AR226-0776
|
Yj5JaE35aL6J17929LebBoNVV |
3 |
|
The document reports on an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 0.92% perfluorooctanesulfonate (PFOS) and other components, indicating that the data may not accurately reflect the toxicity of the fluorochemical due to incomplete characterization of impurities.
|
1975 |
AR226-0795
|
Rjm85yv2nRDLayvNrwkR74Qzk |
9 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating that the test sample, FC-600, consists of 1.0% PFOS among other components, although the specific method and production lot number were not provided.
|
1975 |
AR226-0826
|
jbnrMrd9z04Vz11wvV73nBdZ |
6 |
|
The document reports on an acute toxicity test conducted on bluegill fish (Lepomis macrochirus) using a mixture containing 1.0% perfluorooctanesulfonate (PFOS) and various other components, indicating that the test was performed under static conditions with incomplete characterization of impurities.
|
1975 |
AR226-0827
|
Rjo2ZynVgGbgM9QMKzLXrv947 |
5 |
|
The document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 0.58% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating the test's methodology and conditions, but notes that the data may not accurately reflect the toxicity of the fluorochemical component due to impurities.
|
1975 |
AR226-0872
|
2j655gmw35aZr8KmKOjOddV2g |
9 |
|
The document describes an algicidal activity test of a mixture containing perfluorooctanesulfonate (PFOS) and other components, conducted using Chlorella pyrenoidosa and Phormidium inundatum to assess the toxicity of the test substance under specific conditions.
|
1974 |
AR226-0721
|
7Oq3NB7Rr3MZqjXE96V3Km3ro |
10 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on juvenile rainbow trout, indicating that the test sample is composed of 1.34% PFOS among other components, with the study conducted under static conditions for 96 hours.
|
1974 |
AR226-0722
|
mmn6aaBOY9e7BJLZXKmqQ6YkO |
4 |
|
The document details an acute toxicity test of a PFOS-containing mixture (FC-206) on Daphnia magna, indicating that the test sample comprises 0.67% PFOS among other components, although the toxicity data may not accurately reflect the fluorochemical's effects due to impurities.
|
1974 |
AR226-0787
|
rBDjBwDG2mLB2KzOnMEbpJgyr |
8 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic invertebrate Gammarus fasciatus, revealing a 48-hour median tolerance limit (TL50) value of 5170 mg/L.
|
1974 |
AR226-0788
|
k9aYZqJp472Rnd2aEZ3xYw02b |
8 |
|
This analytical report from Centre Analytical Laboratories details the characterization of surface water samples collected in Cleveland, Tennessee, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
1973 |
AR226-0671
|
o9j39KJOod4MaOqVerNG5dwLr |
8 |
|
The document summarizes biodegradation studies on a mixture containing perfluorooctanesulfonate (PFOS) produced by 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn due to insufficient methodological details.
|
1973 |
AR226-0710
|
rxZyM2N3RrkEqodXvoZ5LV7X0 |
15 |
|
The document reports on acute aquatic toxicity testing of a mixture containing perfluorooctanesulfonate (PFOS) from 3M, revealing varying 96-hour LC50 values ranging from 0.061% to >1000 mg/L across multiple studies.
|
1973 |
AR226-0717
|
Z823V01kL9pp6vGzwqx1po5xY |
28 |
|
The document reports on a microbial inhibition test involving a mixture containing 1.34% perfluorooctanesulfonate (PFOS) produced by 3M, but lacks sufficient methodological details and conclusive results to assess the inhibition effects accurately.
|
1973 |
AR226-0720
|
jmMY9gM92RJRKg3NnYx8NoM3p |
8 |
|
This document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 1.34% perfluorooctanesulfonate (PFOS) and various other components, highlighting the methodology and conditions of the bioassay performed in 1972.
|
1970 |
AR226-0716
|
x1a1xkYGLowjv6bBxeZwgo8Gm |
10 |
|
The document details an acute toxicity test of a PFOS-containing mixture (FC-203) on Daphnia magna, conducted using standard methods, which indicates the test sample's composition and outlines the experimental conditions and procedures.
|
1970 |
AR226-0718
|
3N5ev5xxdZYBV6Yo2Zo8VBoD |
10 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on the aquatic invertebrate species Gammarus fasciatus, using various concentrations of the test substance FC-203, which includes 1.34% PFOS, to assess its toxic effects over a 48-hour exposure period.
|
1970 |
AR226-0719
|
mmKJB1RZ4RLaX53LjZxZ4rqw4 |
10 |
|
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on eastern oyster embryos (Crassostrea virginica), using a Pacific Oyster Bioassay method to assess the impact of the test substance, identified as FC-206, which comprises 0.67% PFOS among other components.
|
1967 |
AR226-0786
|
1Qka5x2JOdBryvnkmvekz54Ya |
8 |
|
This internal correspondence details the results of pooled human serum samples for PFOS collected from European blood banks in 1999, showing consistent findings with previous data, with average concentrations of PFOS in Belgium, the Netherlands, and Germany being 17 ppb, 53 ppb, and 37 ppb, respectively.
|
— |
AR226-0646
|
82bO40opB9VLk3R7pOoGpMyxB |
2 |
|
The document discusses the results of skin and eye irritation assessments conducted on FC-95 (T-1117), a product containing PFOS, by the WARF Institute, indicating it was non-irritating to skin but minimally to mildly irritating to eyes, with recommendations for precautionary labeling.
|
— |
AR226-0647
|
byzGLV7rnGbw0EXqM5XgDvZk |
8 |
|
The document is a final report from SRI International examining the mutagenic activity of 3M Company's Compound T-2816CoC (related to PFOS) using in vitro microbiological assays, which concluded that the compound was not mutagenic or recombinogenic in any of the tests performed.
|
— |
AR226-0648
|
GmeL8b4wVKeXb1edKy67wRdrN |
15 |
|
The document is a final report from SRI International assessing the mutagenic activity of 3M Company's Compound T-2997CoC (related to PFOS) using the Ames Salmonella/microsome assay and yeast assays, concluding that the compound was not mutagenic or recombinogenic in any tests performed.
|
— |
AR226-0649
|
mB432Bv0dKbY6rJ7rd5RO11bd |
18 |
|
The document is a draft electron microscopy report detailing the findings from a 26-week toxicity study of perfluorooctane sulfonic acid (PFOS) in cynomolgus monkeys, indicating that liver lesions observed during treatment have resolved in recovery animals.
|
— |
AR226-0650
|
Y7NmMpOom7L5ML0nMvvQmo3O |
35 |
|
This document reports on a 6-month study of PFOS conducted on cynomolgus monkeys for 3M, detailing various biochemical parameters such as TSH, cholesterol, and lipoprotein levels across different groups.
|
— |
AR226-0651
|
zMvw7GR9BY12xZkGgYM9xz8z |
12 |
|
A 28-day percutaneous absorption study of FC-98, a substance containing PFOS, was conducted on albino rabbits at Riker Laboratories, which indicated dermal absorption but lacked conclusive results due to limited sample analysis.
|
— |
AR226-0653
|
2qro19LXLe6reEZppQBKDZ1Jb |
17 |
|
The document is a final report of a single-dose intravenous pharmacokinetic study of T-6684, a compound related to PFOS, conducted by Corning Hazleton Inc. for 3M, detailing the study's context, quality assurance, and completion date.
|
— |
AR226-0654
|
DD4NXzjdM796kaeqzzN3xkpMN |
37 |
|
This document outlines a pharmacokinetic study of perfluorooctane sulfonyl fluoride (POSF) in male Sprague Dawley rats to assess its oral absorption, clearance, and metabolism to perfluorooctane sulfonate (PFOS), conducted by 3M Chemicals Division under GLP conditions.
|
— |
AR226-0656
|
dYd8NpR0L3x7MR4jm3DN4r55Q |
8 |
|
This master's thesis by Deanna J. Nabbefeld investigates the effects of perfluorooctane sulfonic acid (PFOS) and other fluorocarbons on liver fatty acid-binding protein (L-FABP), finding that PFOS significantly decreases the maximum binding capacity of L-FABP in treated rats.
|
— |
AR226-0652
|
4v7R6b5GL0QwKE9mq9jkbG7mQ |
56 |
|
This document is a final report from Covance Laboratories Inc. detailing a 5-daily dose dermal absorption/toxicity study of the substance T-6684, sponsored by 3M, conducted on rabbits, with a completion date of December 31, 1997.
|
— |
AR226-0655
|
B54vr1GMDLkKxBQ7JMyBL0pQw |
54 |
|
This document reports on an acute oral toxicity study of the substance FM-3422, produced by 3M Company, which determined the LD50 values in male and female rats to be 1615 mg/kg and 1333 mg/kg, respectively.
|
— |
AR226-0657
|
Z44VVK7djDQbDZdBjXG9rqN17 |
14 |
|
The document reports on a study conducted by Riker Laboratories, Inc. that identified a major metabolite, 2-N-ethyl perfluorooctanesulfonamido acetic acid (PFSAA), from the feces of rats after they were administered a carbon-14 labeled N-ethyl FOSE in feed for one week, with the metabolite accounting for at least 50
|
— |
AR226-0658
|
0qRBEpp35Rze0jEo4R73nEm3R |
22 |
|
The document outlines a rat teratology study protocol to assess the embryo/fetal toxicity and teratogenic potential of a test material, identified as T-3352, administered to pregnant rats, in compliance with FDA guidelines.
|
— |
AR226-0661
|
bZvbKyXVqy4R0MkyxjL3prg3 |
14 |
|
The document reports on an acute oral toxicity study of the substance T-306700C conducted on albino rats, finding that the approximate oral LD50 is greater than 5,000 mg/kg, with no observed mortalities or adverse effects during the observation period.
|
— |
AR226-0662
|
by5mz7G8o0x11mrbXKqQe0yk0 |
9 |
|
The document is a final report on a pilot rat teratology study conducted by Hazleton Laboratories America, Inc. for 3M Company, evaluating the effects of N-Et FOSE alcohol on maternal and fetal outcomes.
|
— |
AR226-0659
|
p06kZreM75Y6w5jkyQYZbKkD |
51 |
|
The document is a final report of a rat teratology study (Project No. 154-161) conducted by Hazleton Laboratories for 3M Company, focusing on the effects of N-Et FOSE alcohol, a perfluorinated compound, under Good Laboratory Practice regulations.
|
— |
AR226-0660
|
wZBNq85zBJ1xROKXd8x7wmzQ |
80 |
|
This document is a final report of a single-dose intravenous pharmacokinetic study of T-5904, a compound produced by 3M, conducted on rabbits by Hazleton Wisconsin, Inc.
|
— |
AR226-0663
|
LXnGJe4GNRdwn9gprk52jMdq |
25 |
|
The document is a final report from Hazleton Laboratories detailing an acute oral toxicity study of PFOA (sample T-4416) conducted on rats, following OECD guidelines, with a focus on methodology and results.
|
— |
AR226-0665
|
ByL6XL2eo5LkGNxaMMRbjenm |
23 |
|
The document is a final report from Hazleton Laboratories detailing an acute toxicity study on PFOA (sample T-4416) conducted on rabbits to assess primary dermal irritation/corrosion according to OECD guidelines.
|
— |
AR226-0666
|
Dv3zERBYagB02xrQ5K11KYL04 |
10 |
|
The document is a final report from Hazleton Laboratories assessing the acute ocular toxicity of PFOA (sample T-4416) in rabbits, following OECD guidelines.
|
— |
AR226-0667
|
BRLNoV95rZ79M9ygKBGrmZ1aJ |
18 |
|
The document is an analytical report from Centre Analytical Laboratories detailing the characterization of surface water samples collected from Mobile, Alabama, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
— |
AR226-0673
|
kaEmZ8ODwzaJKkB72QgRDVpNJ |
8 |
|
This analytical report from Centre Analytical Laboratories details the fluorochemical characterization of surface water samples collected from Pensacola, FL, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
— |
AR226-0674
|
ypn64Bg9xoVOJaNLMpOL7Kj5r |
8 |
|
This analytical report from Centre Analytical Laboratories details the fluorochemical characterization of surface water samples from Port St. Lucie, FL, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
— |
AR226-0675
|
NRax1y2ybEzKDrGXE37ajExw |
6 |
|
The document outlines a pharmacokinetic study protocol by 3M to assess the oral absorption, clearance, and biological persistence of Perfluorooctane Sulfonamide (PFOSA) in rats, aiming to investigate its potential conversion to PFOS and improve risk characterization.
|
— |
AR226-0664
|
QM2gDO4bmxob5gao5GN7mVnz6 |
333 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on rainbow trout, indicating a 96-hour LC50 value greater than 400 mg/L, suggesting low toxicity at the tested concentrations.
|
— |
AR226-0715
|
mqgBzeqrOagxrzBEQbzZpMm9O |
4 |
|
The document reports on a biodegradation test of a mixture containing 0.92% perfluorooctanesulfonate (PFOS) conducted by Pace Laboratories for 3M Company, noting significant chemical oxygen demand (COD) and biochemical oxygen demand (BOD) results but lacking detailed methodology and conclusions.
|
— |
AR226-0806
|
EqR5bnMY10N3Xn27rkVx8R3VR |
5 |
|
The document reports that the 96-hour LC50 for a mixture containing 0.5% PFOS (FC-780) was greater than 5000 mg/L, indicating low acute toxicity to the fish species Fundulus heteroclitus.
|
— |
AR226-0869
|
ByQRjkvEd4BaGEMRnrkDKZwj |
3 |
|
The document reports on biodegradation studies of a mixture containing perfluorooctanesulfonate (PFOS) from 3M, indicating that while the majority of the product components are readily biodegradable, no reliable conclusions can be drawn regarding the degradation potential of the fluorochemical component.
|
— |
AR226-0870
|
6RqOBZvJm0j39ox5QDx3NgRLR |
36 |
|
This is a TSCA NCIC Notification Form indicating that the referenced document is claimed as confidential business information under Section 14 of the Toxic Substances Control Act.
|
— |
AR226-0930
|
5L5drZooQJ6M6mjd2aD5L8rRR |
1 |
|
Unreadable document.
|
— |
AR226-0937
|
G6Go2dZ8EaYRQKD5MzZ2QrKDn |
2 |
|
The document outlines a meeting between the EPA and the Fluoropolymer Industry to discuss the safe manufacture and use of fluorinated processing aids (APFO/PFOA) in fluoropolymers, addressing industry practices, regulatory expectations, and environmental impacts.
|
— |
AR226-0938
|
ga1p5kzpbGO5kRy7JjQoEYaY3 |
7 |
|
Unreadable document.
|
— |
AR226-0939
|
bavzNeMzMda5ddkxQq40dNZd3 |
2 |
|
The document summarizes studies conducted by 3M on the foaming characteristics of their AFFF products containing PFOS, highlighting the impact of foaming on wastewater treatment processes and noting that the data lacks agency-approved procedures.
|
— |
AR226-0926
|
DGdzYDmpX3B40QVm5Reyq5wMM |
59 |
|
Unreadable document.
|
— |
AR226-0942
|
6B6nVQG8Zvo73w87wzb3GxJL9 |
1 |
|
Unreadable document.
|
— |
AR226-0944
|
q7XDnN40DOv4vk238Kz6dbrG |
2 |