|
The document reports the analysis of 37 blood samples for perfluorooctanoate (PFOA) conducted by E. I. du Pont de Nemours and Company, detailing the concentrations found in each sample.
|
1981 |
AR226-1608
|
1gZmvgwNdvX9G4mYM3LQzDY3X |
3 |
|
The document reports the analysis of blood samples for perfluorooctanoate (PFOA) conducted by E.I. du Pont de Nemours and Company, detailing the concentrations found in the samples and the methodology used for the gas chromatographic analysis.
|
1981 |
AR226-1609
|
0J8eVX467y95Vab4Koq05v13R |
2 |
|
The document outlines an experimental program at E. I. Du Pont de Nemours and Company to analyze blood samples for FC-143 among employees in Teflon areas and to conduct product analyses for FC-143 in Teflon products, ensuring consistent laboratory procedures for reliable results.
|
1981 |
AR226-1648
|
JwxLxgrNmwrbw6LrnGBkenLe |
2 |
|
The document reports the analysis of TEFLON felt samples for residual C-8 fluorosurfactant, revealing that the unbleached XT-7700 contained 3.5 ppm and the bleached XT-7800 contained 0.7 ppm of equivalent C-8 APFC, with findings consistent with typical levels found in other fluoropolymer products.
|
1981 |
AR226-1649
|
gDaMB2BdYgXEyyR6XaDVQzgqQ |
4 |
|
The document reports on the analytical research conducted by E.I. du Pont de Nemours & Company regarding the removal of FC-143, a perfluorinated compound, from Teflon products, indicating that approximately 30-35% can be extracted through aqueous methods, with higher removal rates observed in SM-3 regenerated yarn compared to SM-2.
|
1981 |
AR226-1650
|
Z4b7V0zGmVmnpN6eQ29Xv3Dzp |
6 |
|
This is a correspondence from the Spruance Research Laboratory discussing the shipment of heat-treated Teflon and Kevlar yarn samples for evaluation, including observations on denier changes and potential issues with the materials.
|
1981 |
AR226-1652
|
3k11BwKk8XexdavNXnE87Xpn |
2 |
|
The document outlines efforts by P. P. Burks to eliminate or control FC-143, a fluorocarbon surfactant supplied by 3M Company, due to its reported embryotoxic effects, detailing successful thermal treatment methods that removed detectable levels of FC-143 from Teflon and Kevlar yarns, while further investigations into the causes of packing failures and alternative removal methods are ongoing.
|
1981 |
AR226-1653
|
MMjd6OJvyr0Kbm6wjkYG6QoO9 |
2 |
|
The document discusses a study by S. S. Shelburne on the thermal treatment of FC-143 in Teflon products, revealing that decarboxylation occurs at elevated temperatures, producing byproducts that require mass spectrometry for identification.
|
1981 |
AR226-1655
|
YDbVp2rjGqXxQyJv6dpdb9E10 |
4 |
|
The document discusses the status and interim processes for controlling FC-143 exposure, detailing the feasibility of ion exchange technology for removing approximately 90% of FC-143, a perfluorinated compound, from dispersion after polymerization, with a focus on commercialization and safety measures.
|
1981 |
AR226-1656
|
RaG4m33mkGxo4QozMn5L2y5Q8 |
13 |
|
The document reports on the analysis of FC-143 levels in Teflon products by E. I. du Pont de Nemours & Company, revealing that thermal treatment at temperatures of 175°C or higher can effectively remove FC-143 sodium salt, primarily through decarboxylation, although this method may negatively impact product performance.
|
1981 |
AR226-1657
|
a48g1a8yyrGNzVkdbXqo244RX |
2 |
|
The document outlines a study conducted by E.I. DuPont de Nemours & Co. on monitoring the levels of FC-143 (ammonium perfluorooctanoate) in the Teflon process due to potential teratogenicity concerns raised by 3M, with objectives including measuring personnel exposure and developing accurate detection methods.
|
1981 |
AR226-1658
|
qmkXmGe5rVnEwnbaRoE9OGXwM |
29 |
|
The document presents a compound-specific method for the quantitative characterization of organic fluorochemicals, including PFOA and PFOS, in biological matrices using negative ion electrospray tandem mass spectrometry, highlighting its application in analyzing human sera samples.
|
1980 |
AR226-0191
|
QX87Oo2xe4qkLGMaZjZnqaG36 |
22 |
|
The document reports on an oral teratology study of FC-95, a perfluorinated compound produced by 3M, which found that administration to pregnant rats resulted in teratogenic changes in the lens of the eye, particularly at a dose of 10 mg/kg/day, while lower doses did not show maternal toxicity or embryotoxic effects.
|
1980 |
AR226-0016
|
BRodwR71n6JyonO9d4jmjBQzk |
33 |
|
The document details the synthesis and characterization of carbon-14 labeled N-Ethyl FOSE (2-N-ethylperfluorooctanesulfamido ethanol) conducted by 3M and Riker Laboratories, confirming its specific activity and high purity for use in metabolism studies.
|
1980 |
AR226-0268
|
QknnBXORdw2G7OzmGpDRD6jRo |
20 |
|
The document details an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) on eastern oyster larvae (Crassostrea virginica), noting that the test sample is FC-203 with 1.34% PFOS and various other components, and describes the methodology used for the toxicity assessment.
|
1980 |
AR226-0726
|
1gk2VBV6mrNEa550w0n8Y7Gma |
12 |
|
The document details an experiment assessing the foaming effects of a mixture containing perfluorooctanesulfonate (PFOS) as part of the FC-203A formulation, conducted using a modified OECD screening test, although the results may not accurately reflect the fluorochemical component due to impurities.
|
1980 |
AR226-0738
|
aDa0vQYxZZqx52MLDoXzD1KJY |
6 |
|
The document details an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using the fish species Fundulus heteroditus, following a specific protocol, with results indicating the need for caution due to the presence of impurities in the test sample.
|
1980 |
AR226-0743
|
V3Jp0dDemDyO3xMDR7vBVRZ0w |
16 |
|
The document reports on a study evaluating the foaming effect of a mixture containing 0.67% PFOS and other components, indicating that the data does not accurately reflect the degradation potential of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1980 |
AR226-0779
|
eYroOO2wL3kevBD6qDyQ5m9m |
3 |
|
The document details a biodegradation test (OECD 301E) conducted on a mixture containing 0.67% PFOS, produced by 3M, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities.
|
1980 |
AR226-0778
|
Gm4NR6BQp9VRL2VvZR78Oq6Vx |
34 |
|
The document describes an acute toxicity test conducted on a mixture containing perfluorooctanesulfonate (PFOS) using juvenile mummichogs (Fundulus heteroclitus), noting that the test sample was primarily composed of water and various chemicals, but the LC50 values could not be calculated due to incomplete characterization of the mixture's impurities.
|
1980 |
AR226-0804
|
v2pX5BNdKBap1YjvRG6KVv7R |
14 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 1.0% perfluorooctanesulfonate (PFOS) from a 3M production lot, indicating potential toxicity levels based on the test conditions and methodology outlined.
|
1980 |
AR226-0837
|
4JR9a5e1z4NdD2xEw3pmvm6mN |
17 |
|
The document reports on a biodegradation test (OECD 301D) for a mixture containing 0.58% PFOS, conducted by 3M, indicating that the data does not accurately reflect the degradation potential of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1980 |
AR226-0871
|
V359YKRKayyg2ZpnLbk1JoB3q |
11 |
|
The document discusses a comparison of two N-EtFOSE alcohols, FM-3422 and FM-3924, used in teratology studies at Riker Laboratories, detailing their compositions and production methods.
|
1980 |
AR226-0277
|
MJqBL6M1yk23E3o6vgx8RJXmj |
1 |
|
The document reports on an oral teratology study of FM-3422, revealing that it caused teratogenic effects such as developmental eye abnormalities, cleft palates, and skeletal malformations in rat fetuses when administered to pregnant Sprague-Dawley rats during organogenesis, while also noting maternal toxicity at higher doses.
|
1980 |
AR226-0280
|
0gn2YxMMxgk8XpV8p87R98NnM |
26 |
|
The document compares two formulations of N-EtFOSE Alcohol (FM-3422 and FM-3924) used in teratology studies, detailing their composition and production methods.
|
1980 |
AR226-0281
|
zokG9mBdy5eb88ozEEQqyamqm |
1 |
|
The document compares two formulations of N-EtFOSE alcohols (FM-3422 and FM-3924) used in teratology studies, detailing their chemical compositions and production methods.
|
1980 |
AR226-0284
|
4nbbbaJrr49Qg2BZyw1Zmj |
1 |
|
This document reports on a biodegradation test conducted by 3M Company on a mixture containing perfluorooctanesulfonate (PFOS) and other components, revealing high Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) values, but lacking reliable conclusions due to insufficient characterization of the test substance and methodology.
|
1980 |
AR226-0924
|
YDDVYR8Yj4pQgQgw7ZQgeojvK |
12 |
|
The document reports on an acute toxicity test of a mixture containing perfluorooctanesulfonate (PFOS) conducted on fathead minnows (Pimephales promelas), indicating that the test sample was a 1.356% solution of L-4647 with 6.6% PFOS and various other components, although the method and specific toxicity results are not provided
|
1980 |
AR226-0925
|
Z6vb9yjDOqNNy9qxR7QQRwjY |
6 |
|
The document reports on an acute toxicity test of Perfluorodecanesulfonate (PFDS) on the aquatic invertebrate Daphnia magna, conducted by 3M in 1988, using a mixture containing approximately 22-26% PFDS, with results indicating the test conditions and monitoring parameters.
|
1980 |
AR226-0389
|
09K16r8QBvO2MyQY660g6X0b |
18 |
|
The document reports on a study conducted by Riker Laboratories, a subsidiary of 3M, which found that after a single oral dose of the perfluorinated compound FC-143 (mean dose of 11.0 mg/kg) to male rats, at least 93% of the total carbon-14 was absorbed within 24 hours, with a plasma elimination half-life of 4.
|
1980 |
AR226-0455
|
31pZanDV235KOo0r6VX1owpO |
15 |
|
The document is an update on a retrospective cohort mortality study conducted by University of Minnesota epidemiologists on employees at the 3M Chemolite Plant, which found no statistically significant differences in mortality rates, including prostate cancer deaths, among workers exposed to perfluorinated compounds.
|
1980 |
AR226-0471
|
0eRQOYagR2z95Beop9GonR2J |
28 |
|
The document details a biodegradation study of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt) conducted by 3M Company, indicating unreliable results due to insufficient characterization of the test substance and method, with no reliable conclusions drawn from the study.
|
1980 |
AR226-0492
|
Lb68mepYZxdpjGw6Rn99ryrz |
9 |
|
The document reports on a study conducted by 3M Company evaluating the acute toxicity of ammonium perfluorooctanoate (PFOA ammonium salt) on activated sludge respiration, finding no acute inhibitory effect at a concentration of 1000 mg/L after 7 minutes of contact time.
|
1980 |
AR226-0505
|
5LBZ9RRXxwQ4QLdZxLNbN5nb8 |
4 |
|
The document reports that SRI International conducted in vitro microbiological mutagenicity assays on 3M Company compounds T-2540 CoC and T-2541 CoC, finding that neither compound exhibited mutagenic or recombinogenic activity in any of the tested assays.
|
1979 |
AR226-0208
|
NrvVgkm5bNZR7rO4L0pqr7gy |
23 |
|
A 28-day percutaneous absorption study of FC-129, a perfluorinated compound, conducted on albino rabbits at Riker Laboratories, Inc. revealed significant mortality and adverse behavioral reactions, indicating potential toxicity, although definitive conclusions on dermal absorption could not be established due to limited serum analysis.
|
1979 |
AR226-0224
|
zgBLjaG9e9qkL1royd2Rq25n |
15 |
|
The document reports on a 28-day dermal absorption study of FC-128, a perfluorinated compound, conducted on albino rabbits at Riker Laboratories, which found evidence of dermal absorption but lacked sufficient data for definitive conclusions.
|
1979 |
AR226-0223
|
YbBKqQq6vbODQNGdGwJMRojK |
16 |
|
The document outlines a ninety-day subacute toxicity study of the compound FM-3422, produced by 3M Company, involving rhesus monkeys and detailing methods, observations, and results related to clinical and pathological assessments.
|
1979 |
AR226-0256
|
2qnRrYMKBk2Q3dz69r7K4dK06 |
35 |
|
This document reports on pharmacokinetic studies of [14C]PFOS conducted on male Charles River CD rats, revealing that at least 95% of an oral dose was absorbed within 24 hours, with significant excretion observed in urine and feces over 89 days, and no evidence of metabolic conversion of PFOS was found.
|
1979 |
AR226-0004
|
wq7kpXkeg3enM2NkZz4vMj8mE |
2 |
|
The document details the synthesis and characterization of carbon-14 labeled FC-95-14c, a sulfonic acid salt produced by 3M's Commercial Chemicals Division, which was found to be at least 99% radiochemically pure and suitable for metabolism studies.
|
1979 |
AR226-0005
|
vVk43qRVeG7eLraear28eqrgw |
18 |
|
This document reports on a study conducted by Riker Laboratories in 1979 examining the excretion and tissue distribution of carbon-14 labeled FC-95, a perfluorinated sulfonic acid, in male rats following intravenous administration, revealing significant urinary and fecal excretion rates and tissue concentrations.
|
1979 |
AR226-0006
|
6B2Y0ZJggmzojox9RKXqde26R |
19 |
|
The document reports on a study conducted by Riker Laboratories, Inc. on the absorption and elimination of FC-95 (a potassium salt of a perfluorinated sulfonic acid) in male rats, finding that at least 95% of a single oral dose is absorbed within 24 hours and has a plasma elimination half-life of 7.5 days.
|
1979 |
AR226-0007
|
QXKpJw96VN7kaqOMV4YME98D6 |
18 |
|
The document is an analytical report from Centre Analytical Laboratories detailing the characterization of surface water samples collected in Decatur, Alabama, specifically analyzing for perfluorinated compounds including PFOS, PFOSA, and POAA, as requested by 3M Environmental Laboratory.
|
1979 |
AR226-0672
|
KJ7Zkn75vLxNpJGO2NQprvLRN |
7 |
|
This document reports on a biodegradation study of Perfluorooctanesulfonate (PFOS) DEA salt conducted by 3M Company, indicating that while the non-fluorinated moiety (2,2'-iminobis[ethanol]) is likely to biodegrade in aerobic conditions, the potential for biodegradation of the fluorochemical moiety remains uncertain.
|
1979 |
AR226-0059
|
1g33JqpYL9k32GbpBjrRz5vRd |
11 |
|
This document is an analytical report from Centre Analytical Laboratories detailing the fluorochemical characterization of drinking water samples from Decatur, Alabama, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using liquid chromatography/tandem mass spectrometry (LC/MS/MS).
|
1979 |
AR226-0068
|
qd0Z064MBRvawe6kwMLeBYa6M |
8 |
|
The document reports on an activated sludge respiration inhibition test conducted by 3M Company on perfluorooctanesulfonate (PFOS DEA salt), indicating that the test material showed no inhibitory effect at a concentration of 1000 mg/L over a 7-minute exposure.
|
1979 |
AR226-0116
|
omjpgZgmz699OzzwRmJZ7K2j8 |
4 |
|
The document is a 90-day subacute toxicity study on the fluorochemical surfactant FC-95 produced by 3M Company, conducted on rhesus monkeys to assess its effects on health.
|
1979 |
AR226-0138
|
nNNmBRE04Zm8191aZ8q2GN8za |
24 |
|
The document details an acute toxicity test conducted on mummichogs (Fundulus heteroditus) using a mixture containing 1.34% perfluorooctanesulfonate (PFOS) to assess its effects, following a standard marine bioassay procedure.
|
1979 |
AR226-0724
|
ym77p0NQdKG2eDEqYwnQ32aK4 |
15 |
|
This document details an acute toxicity test conducted on the Eastern Oyster (Crassostrea virginica) using a test substance identified as PFOA, following standard practices for static acute toxicity tests, with results indicating specific toxicity levels.
|
1979 |
AR226-0725
|
KGpYpovJ2NDz7JGX2jVbZKk1o |
12 |
|
The document reports on a 28-day percutaneous absorption study of FC-95 conducted on albino rabbits at Riker Laboratories, which found no mortalities but noted hyperactivity and body weight loss in one male rabbit, with preliminary serum analysis indicating dermal absorption potential of FC-95.
|
1979 |
AR226-0155
|
qmMDV0komvQN5p12GQ1ma8LwK |
16 |
|
The document reports on a 28-day percutaneous absorption study of FC-99 conducted on albino rabbits at Riker Laboratories, Inc., indicating dermal absorption potential but lacking conclusive results due to limited serum analysis.
|
1979 |
AR226-0156
|
v6DKbo366zODeNjEVXQ3kE7eR |
16 |
|
The report discusses the assessment of mitochondrial bioenergetics in rats treated with dietary FC10, highlighting the confounding effects of pentobarbital on pyruvate oxidation, which hindered the establishment of a dose-response correlation, and suggests alternative methods for analyzing metabolic dysfunction in exposed animals.
|
1979 |
AR226-0168
|
aJND548jdb2qXravmX78V2z6Y |
7 |
|
The document reports on an acute toxicity test of a mixture containing 0.92% PFOS (perfluorooctanesulfonate) conducted on fathead minnows (Pimephales promelas) to assess the effects of the substance, with details on the test conditions and methodology.
|
1979 |
AR226-0796
|
vyp1GGY9n7OJRJGr933RoVDeq |
10 |
|
The document details an acute toxicity test conducted on fathead minnows (Pimephales promelas) using a mixture containing 0.92% PFOS, revealing the test conditions and methodology but noting that data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized impurities.
|
1979 |
AR226-0797
|
29G3Gqde2k7XaaN80JNwE7 |
7 |
|
The document reports on an acute toxicity test of a mixture containing 0.92% PFOS, conducted on Daphnia magna, indicating the test conditions and parameters used, although it notes that the data may not accurately reflect the toxicity of the fluorochemical component due to incomplete characterization of impurities.
|
1979 |
AR226-0798
|
Jr8ekaVYDdZz38BkNjgk0Ea9e |
6 |
|
The document details a microbial inhibition test on a mixture containing 0.92% perfluorooctanesulfonate (PFOS) produced by 3M, indicating that the data may not accurately reflect the toxicity of the fluorochemical component due to incompletely characterized concentrations of impurities.
|
1979 |
AR226-0799
|
npLXv909Mm8YLwjopaMo12e2X |
7 |
|
The document reports on an activated sludge respiration inhibition test conducted on a mixture containing 0.92% PFOS, produced by 3M, which found no acute inhibitory effects on activated sludge respiration at a concentration of 1000 mg/L.
|
1979 |
AR226-0800
|
byDx7d69ReVrXRrm7dXopmzJ0 |
5 |
|
The document details an acute toxicity test conducted on the fish species Fundulus heteroclitus using a mixture containing 0.58% perfluorooctanesulfonate (PFOS) and other components, following a standard marine bioassay procedure to determine the LC50 values over a 96-hour exposure period.
|
1979 |
AR226-0873
|
zQmdaRnZw0jJYNyrzXK54w6Ym |
15 |
|
This document reports on a biodegradation test of a mixture containing perfluorooctanesulfonate (PFOS) conducted by 3M Company in 1979, noting high biochemical oxygen demand (BOD) values but lacking detailed methodology and sample characterization.
|
1979 |
AR226-0875
|
dQ6peOGOXO4KYe6xb591J3LJQ |
9 |
|
The document reports on an activated sludge respiration inhibition test for a mixture containing 1.0% PFOS, indicating no acute inhibitory effect on activated sludge respiration at a concentration of 1000 mg/L after 7 minutes of contact time.
|
1979 |
AR226-0877
|
5DM475e5XX1Qo0K0J2mvyGQre |
4 |
|
The document reports on an acute oral toxicity study of T-2574COC, a perfluorinated compound, conducted by Riker Laboratories, which determined an approximate LD50 between 5,000 and 1,000 mg/kg in albino rats, with significant behavioral reactions and mortality observed at the higher dosage.
|
1979 |
AR226-0294
|
QJLJRQG0Y8Xq85Dy0e4gpgw0R |
11 |
|
The document details a modified OECD 301E biodegradation test conducted on a mixture containing 0.67% perfluorooctanesulfonate (PFOS) produced by 3M in Antwerp, Belgium, indicating that the data may not accurately reflect the biodegradation potential of the fluoro-chemical component due to incompletely characterized concentrations of impurities.
|
1979 |
AR226-0889
|
ypjzJpJ0qdqgXBzB29ekJr464 |
34 |
|
The document reports on a two-week oral rangefinding toxicity study of T-2509CoC in rats, conducted by Riker Laboratories and sponsored by the EPA, which aimed to determine the acute oral ALD50 and assess the effects of the compound on various tissues.
|
1979 |
AR226-0959
|
wgyZErj0EQBXXXgmv30dMjoq4 |
30 |
|
The document details an environmental sampling study conducted by 3M in 1979 to analyze bioaccumulation of N-Ethylperfluorooctanesulfonamide (EtFOSA) in fish from the Tennessee River near a 3M fluorochemical manufacturing facility, noting the lack of standardized sampling procedures.
|
1979 |
AR226-0343
|
1QRXOYrjox60omNy5kv3nL6KZ |
36 |
|
The document reports on a 1979 study by 3M Company investigating the photodegradation of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol) in soil, concluding that no reliable results could be derived due to inadequate methodology and uncharacterized purity of the test substance.
|
1979 |
AR226-0362
|
6BLJJzyObZZGdQGGpe3XjeRX4 |
12 |
|
The document contains comments by Professor Stephen A. Boyd on the 3M Technical Report regarding the analytical methodology for FM 3422, highlighting concerns about the octanol-water partition coefficient and its implications for predicting the solubility of the compound in water.
|
1979 |
AR226-0366
|
G6Dqxxyqo7JJV9M83OkMkD82r |
3 |
|
This document details a 1979 bioaccumulation study of N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE alcohol) in fish samples collected from the Tennessee River, noting the lack of standardized sampling procedures and the specific methods used for tissue analysis.
|
1979 |
AR226-0371
|
EvR047V3VDrKZzq3d1vwGBk5j |
36 |
|
The document reports on the analysis of serum samples from a Bio/Dynamics inhalation study of FC-143, focusing on the levels of organic and inorganic fluoride in male and female rats.
|
1979 |
AR226-0418
|
EvgQDDqV2bwvqB260jnE88Qx4 |
2 |
|
The document reports on a 28-day percutaneous absorption study of T-2618CoC, a perfluorinated compound, conducted on albino rabbits at Riker Laboratories, which found no significant adverse effects but indicated dermal absorption potential, although conclusive results were limited due to the small sample size.
|
1979 |
AR226-0446
|
37DpVww7JVMLExNJpvBBGq1DE |
16 |
|
The document details a bioaccumulation study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol) in fish samples collected from the Tennessee River, conducted by 3M in 1979, although it lacks specific guidelines for sampling procedures and information on the fish's capture locations.
|
1979 |
AR226-0971
|
aJMJRG53OXBzwmXaRp3w8rqyX |
37 |
|
The document reports on a bioconcentration study of N-methylperfluorooctane sulfonamidoethanol (N-MeFOSE alcohol), revealing its n-octanol/water distribution coefficients to be 52,900 and 60,600 for two test concentrations, indicating significant hydrophobicity.
|
1979 |
AR226-0972
|
XR0koQ3yGvYmpNLXre7xkVq3x |
8 |
|
The document details the synthesis and characterization of carbon-14 labeled FC-143, conducted by Riker Laboratories, Inc. for metabolism studies, reporting a specific activity of 0.507 ± 0.012 pCi/mg and a radiochemical purity of at least 98%.
|
1979 |
AR226-0456
|
da7xpw2GEYJ2N1z9VeEMYwm65 |
17 |
|
The document reports on a study conducted by S. J. Gibson and J. D. Johnson in 1979, which found significant sex differences in the excretion rates of the perfluorinated compound FC-143 (ammonium salt of a perfluorinated carboxylic acid) in male and female rats, with females excreting nearly all of the dose via urine within
|
1979 |
AR226-0457
|
JvyOdew2XBGzKjG9dkJ59YyEe |
20 |
|
The document is a report from the International Research and Development Corporation detailing a ninety-day subacute rat toxicity study on the compound FM-3422, sponsored by 3M Company, which likely involves perfluorinated compounds such as PFOA or PFOS.
|
1978 |
AR226-0255
|
VJZg2MDrarKMjd80rDj7307zK |
53 |
|
The document details a 1978 study conducted by 3M to assess the bioaccumulation of perfluorooctanesulfonate (PFOS) in bluegill sunfish exposed to effluent from their Decatur, AL plant, finding PFOS present in the effluent-exposed fish while no fluorochemicals were detected in the control group exposed to river water.
|
1978 |
AR226-0061
|
kmn36Kna1BrVyZO97XkggwEwB |
9 |
|
This document summarizes various ecotoxicity tests conducted by Wildlife International, Ltd. on PFOS, including acute toxicity tests with different aquatic species and life-cycle studies, aimed at assessing the environmental impact of PFOS.
|
1978 |
AR226-0081
|
DG4dYE3bB20Jm2xvEmzRNVxGa |
3 |
|
This document summarizes a 1981 toxicity study conducted by 3M Company on perfluorooctanesulfonate (PFOS) using the aquatic plant species Selenastrum capricomutum, reporting nominal EC50 values but noting issues with sample purity and statistical reliability.
|
1978 |
AR226-0106
|
BXX3wezNVgzddm5ry7G2K7Gw |
18 |
|
This research report submitted to 3M Company investigates the effects of continuous aqueous exposure to 14C-78.02 on the hatchability, growth, and survival of fathead minnow (Pimephales promelas) eggs and fry, finding that survival was the most sensitive indicator of toxicity with an estimated MTC value between >1.0 mg/L and <1.9 mg/L
|
1978 |
AR226-0108
|
Jr1dRdO6qvEkjv03X8gyMQnVK |
29 |
|
The document reports that 3M Company compounds T-2247 CoC and T-2248 CoC were tested for mutagenic activity using the Ames Salmonella/microsome assay and found to be non-mutagenic and non-recombinogenic in all assays conducted.
|
1978 |
AR226-0134
|
VYDjdX8Ve663N2b5azvkNENq |
22 |
|
The report details an in vitro study conducted by SRI International on three 3M Company compounds (T-2136 CoC, T-2138 IM, and T-2140 IM) to assess their mutagenic activity using the Ames test with Salmonella typhimurium and Saccharomyces cerevisiae, concluding that none of the compounds exhibited mutagenic properties.
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1978 |
AR226-0683
|
xjMaDMKdbmqYnV730oedmmDvy |
17 |
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The document is a report on a ninety-day subacute rat toxicity study of the fluorochemical surfactant FC-95, sponsored by 3M Company and conducted by the International Research and Development Corporation.
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1978 |
AR226-0139
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Eq9kXLKBOEz5a6K28qLkbmR7n |
55 |
|
The document details an acute toxicity test conducted on bluegill sunfish (Lepomis macrochirus) using a mixture containing 0.67% PFOS, produced by 3M, to evaluate its effects over a 24-hour exposure period.
|
1978 |
AR226-0791
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5LDgKvvxqkmLYan2On0eQnvOz |
3 |
|
The document reports on a biodegradation test of a mixture containing 0.92% perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing high levels of Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD), but lacking adequate characterization and reliability.
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1978 |
AR226-0794
|
6wEmnOoM99pzkJVz8BEYDa95d |
4 |
|
The document reports on an acute oral toxicity study of Fluorad Fluorochemical Surfactant FC-95, produced by 3M Company, which determined the LD50 values in male and female rats to be 233 mg/kg and 271 mg/kg, respectively.
|
1978 |
AR226-0955
|
QX8e6JEYaXBEyNMKroeKamMDo |
11 |
|
The document details a bioconcentration study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol) using channel catfish to determine its aquatic bioconcentration factor, following a 3M derived method, although specific details on fish size, loading, and water chemistry are not provided.
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1978 |
AR226-0352
|
yaJpb0GKNB5x9mqKX3N0OyaE |
7 |
|
The document reports on a 1978 study by 3M Company that analyzed the bioaccumulation of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE alcohol) in bluegill sunfish exposed to effluent from their Decatur, AL plant, finding 7 ppm of the substance in the exposed fish while no fluorochemicals were
|
1978 |
AR226-0354
|
0gR3DEMnm876mYNV48oGGQ3Xx |
10 |
|
The document reports on a study conducted by E G & G, Bionomics Aquatic Toxicology Laboratory for 3M Company, which found that continuous aqueous exposure to the substance 78.01 did not adversely affect hatchability, survival, growth, or weight of fathead minnow (Pimephales promelas) eggs and fry.
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1978 |
AR226-0358
|
RjMEaz1qJKDKXJkMNa82X2oRB |
16 |
|
This document reports on histopathological examinations of fathead minnows (Pimephales promelas) exposed to the substance 78.01, as part of a study submitted to 3M Company, to assess the effects of this compound on the fish following a prior egg and fry test.
|
1978 |
AR226-0359
|
MMd30qOxGvnmg6VxErBkOEVBx |
7 |
|
The document reports on a photodegradation study of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE Alcohol), indicating that no photodegradation occurred after 31 days in a water/methanol/acetonitrile solution.
|
1978 |
AR226-0363
|
LZ23bN4wKb9X1zJqze3mxKab |
20 |
|
The document reports on a 1978 study by 3M Company investigating the bioaccumulation of perfluorooctanesulfonylamido(ethyl)acetate (PFOSAA) in bluegill sunfish exposed to effluent from their Decatur, AL plant, finding no detectable levels of the substance in the fish.
|
1978 |
AR226-0403
|
NemajaQzO7azdDmMoq8v4k8MR |
9 |
|
The document is a final report on the mutagenicity evaluation of T-2015 CoC, submitted to 3M Company, which concluded that T-2015 CoC did not demonstrate genetic activity in the Ames Salmonella/Microsome assay and was considered not mutagenic under the test conditions.
|
1978 |
AR226-0429
|
Rjm9nXkLMr7MEEK6yZrw6V4vB |
11 |
|
This interoffice correspondence discusses the results of a rat toxicity study on FC-143, revealing that male rats accumulate significantly higher levels of FC-143 in serum compared to female rats, prompting a recommendation for further study.
|
1978 |
AR226-0442
|
bOB6BxgL5LvdQ4bGDMRZEDqo |
2 |
|
The document discusses the results of a rat toxicity study on FC-143, indicating that male rats accumulate approximately 100 times more FC-143 in their livers compared to female rats, with specific liver concentration measurements provided.
|
1978 |
AR226-0443
|
JJOkVmpRZJrq53dV6701Gr7RK |
1 |
|
The document is a report on a ninety-day subacute rat toxicity study of the fluorochemical FC-143, sponsored by 3M Company, detailing clinical methods, results, and pathological studies related to the compound's effects.
|
1978 |
AR226-0441
|
mbpe1oDY0yOpRXoLZ3m27krwd |
51 |
|
The document reports on a ninety-day subacute toxicity study of Fluorad Fluorochemical FC-143, sponsored by 3M Company, which found that rhesus monkeys administered the highest dosage of 100 mg/kg/day experienced mortality within weeks 2 to 5, while those at 30 mg/kg/day also showed significant adverse effects.
|
1978 |
AR226-0447
|
Eq6QMopOx16aLG8GbrZV2G89V |
41 |
|
The document details a series of physician reports from 3M's medical surveillance program conducted between 1978 and 1991 at the Cottage Grove facility, where PFOA products were manufactured, indicating that no abnormalities related to fluorochemical exposure were found in employees despite the presence of organic fluorine in serum samples.
|
1978 |
AR226-0478
|
gEDOYB5Eq6GyRwde4w1K9w4Mq |
1 |
|
This document details a soil adsorption study of perfluorooctanoic acid ammonium salt (PFOA ammonium salt) conducted in 1978, using 14C-labeled test substances to evaluate their interaction with Brill sandy loam soil, although the purity of the test sample was not fully characterized.
|
1978 |
AR226-0488
|
O3QNBOvRybQOR7wpgv4kqwwmK |
19 |
|
The document reports on a biodegradation study of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), conducted by 3M, which found no biodegradation over a 2.5-month period using activated sludge as inoculum.
|
1978 |
AR226-0489
|
pmz90yw3yn44zy1K4KekanOJB |
19 |
|
The document reports on a photodegradation test of perfluorooctanoic acid, ammonium salt (PFOA ammonium salt), indicating that no photodegradation was detected after 30 days of exposure to simulated sunlight.
|
1978 |
AR226-0490
|
kB6RkXQdMj8L9jbxDZ7z1RyD |
15 |
|
The document details a 1978 study by 3M Company investigating the bioaccumulation of perfluorooctanoic acid (PFOA ammonium salt) in bluegill sunfish exposed to effluent from their Decatur, AL plant, finding no detectable amounts of PFOA in the fish samples.
|
1978 |
AR226-0491
|
BRdjqKEOyojwjnYEzbxRjZKgm |
16 |
|
The document summarizes various ecotoxicity studies conducted by 3M Environmental Laboratory on the acute and chronic toxicity of PFOA (specifically FC-143) to different aquatic organisms, including fathead minnows and bluegill sunfish, along with assessments of bioaccumulation and other related tests.
|
1978 |
AR226-0497
|
2Ryav49D99axXDLoOdakd4QOb |
6 |