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This is a cover letter addressed to the USEPA regarding fluorochemical submissions, with references to toxicology, epidemiology, and environmental studies.
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2002 |
AR226-1051
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x5rJzDDkR9JXv0LvzeaZrzQg |
1 |
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The document is a bibliography of studies related to perfluorooctanesulfonate (PFOS) and N-ethyl perfluorooctane sulfonamide (N-EtFOSA), highlighting various research findings on their environmental distribution, toxicology, and analytical methods.
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2002 |
AR226-1051
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6BVdBVkn4X0YaDwoz7RY92Q61 |
3 |
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3M Specialty Materials submitted a compact disc to the EPA containing new study reports and analytical data on perfluorooctane sulfonates and related compounds, continuing their voluntary data sharing on fluorochemicals as part of an ongoing dialogue with the agency.
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2002 |
AR226-1051
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3NQYVRQB45b31N2QXgqrrvexJ |
2 |
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The document contains environmental studies and ecotoxicity reports related to PFOS and PFOA, including acute toxicity tests on rainbow trout and sheepshead minnows, as well as a lifetime drinking water health advisory for PFOA from 3M.
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2002 |
AR226-1051
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R8kvYLXnLwMKx9wBKyN4k2Ek |
1 |
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This document details various toxicology and epidemiology studies conducted by 3M on perfluorooctanesulfonate (PFOS), including a 26-week study in monkeys and a 104-week dietary chronic toxicity and carcinogenicity study in rats, along with associated analytical laboratory reports.
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2002 |
AR226-1051
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OEy3gbZYLBrdOrMZab3yLajoM |
2 |
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The document outlines 3M's Lifetime Drinking Water Health Advisory for perfluorooctanoate (PFOA), establishing a reference dose of 2 ug/kg-day based on animal studies, leading to a calculated drinking water exposure level of 70 ug/L and a lifetime advisory level of 14 ug/L for community exposure considerations.
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2002 |
AR226-1051
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pm8Y9Va0w5OQ9bRM9LMJ2E6ba |
14 |
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The document is a final report on a 26-week capsule toxicity study of Perfluorooctane Sulfonic Acid Potassium Salt (PFOS) conducted on Cynomolgus monkeys by Covance Laboratories for 3M, indicating compliance with EPA Good Laboratory Practice regulations except for one analysis.
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2002 |
AR226-1051
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nkgq4nr7ObVr98BNjBz4X2xZ8 |
1086 |
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This document is a final report of a 96-hour static acute toxicity test conducted by Wildlife International, Ltd. on Perfluorooctanesulfonate (PFOS) using rainbow trout, sponsored by 3M Corporation, and compliant with Good Laboratory Practice standards.
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2001 |
AR226-1051
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bOvxxn82R8dwv8am7KjnZL2Vk |
42 |
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This document is a final report on a 96-hour static-renewal acute toxicity test of Perfluorooctanesulfonate (PFOS) conducted with the sheepshead minnow, submitted by Wildlife International, Ltd. to 3M Corporation, and completed in compliance with Good Laboratory Practice Standards.
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2001 |
AR226-1051
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v1MD5exEyoo1YLa7Lxz72a1g6 |
46 |
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The document details an acute toxicity study of Perfluorooctanesulfonate (PFOS) on juvenile rainbow trout (Oncorhynchus mykiss), conducted under GLP conditions, which aimed to determine the LC50 values after a 96-hour exposure to various concentrations of PFOS sourced from a 3M lot.
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2001 |
AR226-1051
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B500ZapxbjD7pp4QLpbGL723m |
4 |
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The document reports on an acute toxicity study of Perfluorooctanesulfonate (PFOS) conducted on juvenile sheepshead minnows, indicating a purity of 86.9% and detailing the testing methodology and conditions used to assess the substance's impact on aquatic life.
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2001 |
AR226-1051
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91M7R3QpV9b4gRwpY61em8VyL |
5 |
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The document is an analytical report from 3M Environmental Laboratory detailing the presence and concentration of PFOS, M556, PFOSAA, and PFOSA in the liver and sera of rats exposed to EtFOSE-OH, completed on May 31, 2001.
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2001 |
AR226-1051
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mmqb65xg2vrmqgyonj9z0XY9O |
143 |
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The document reports on a 104-week dietary carcinogenicity study conducted by 3M, analyzing the presence and concentration of PFOS and related compounds in serum and liver samples of rats exposed to N-Ethyl Perfluorooctanesulfonamido Ethanol.
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2001 |
AR226-1051
|
EmYB08qYzJGm0VRn0Xy05Empb |
212 |
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The document reports on a 104-week dietary carcinogenicity study conducted by 3M, analyzing the presence and concentration of PFOS and related compounds in serum and liver samples of rats exposed to N-Ethyl Perfluorooctanesulfonamido Ethanol, completed on June 6, 2001.
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2001 |
AR226-1051
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OzZy6142RXEEkJJed8ke6LKjM |
310 |
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The document is a final report on a 4-week capsule toxicity study of Ammonium Perfluorooctanoate (APFO) conducted on Cynomolgus monkeys by Covance Laboratories, sponsored by the APME Ad-Hoc APFO Toxicology Working Group, and completed on December 18, 2001, with compliance to EPA Good Laboratory Practice Standards noted.
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2001 |
AR226-1051
|
2NJQaKJgeb9VgjdG2yNoa5ep6 |
159 |
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This document is a final report on a 26-week capsule toxicity study of Ammonium Perfluorooctanoate (APFO) conducted on Cynomolgus monkeys by Covance Laboratories, sponsored by 3M, which adhered to EPA Good Laboratory Practice Standards with some exceptions noted.
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2001 |
AR226-1051
|
qd6eY9aBRBkryNbmXx6rDZj4n |
463 |
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The document is an analytical report from 3M Environmental Laboratory detailing a 26-week toxicity study of Ammonium Perfluorooctanoate (APFO) in cynomolgus monkeys, focusing on the presence and concentration of perfluorooctanoate in various biological samples, conducted in compliance with EPA Good Laboratory Practice standards.
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2001 |
AR226-1051
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3QK89gmzjBY5jBJbR1JVV410E |
411 |
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The document reports on a stability test for perfluorooctanesulfonate-potassium salt (PFOS) conducted by 3M, which found no evidence of direct or indirect photolysis degradation under various light exposure conditions.
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2000 |
AR226-1051
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8ZK8j4Jkzmmepa0BJvdDBBN5 |
2 |
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This is a notice from 3M regarding the submission of documents to the EPA related to fluorochemistry, emphasizing that the documents are for read-only purposes and that original paper copies will be maintained for accuracy.
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— |
AR226-1030
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ppy5GQzRDazQEY0j0Ok1rJ4r6 |
1 |
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The document reports on a 104-week dietary chronic toxicity study of Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) in rats, conducted by 3M Environmental Laboratory, focusing on the determination of PFOS concentrations in liver and serum specimens.
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— |
AR226-1051
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dQgmB1686DybLBdJLQdDny9y6 |
181 |
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This document is a notice from 3M regarding a compact disk containing information submitted to the EPA about fluorochemistry, intended for read-only access.
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AR226-1051
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a11e7RX9B6gNbaV6QLE0jb5Xe |
1 |