CD 11 — AR226-1030a

EPA administrative record segment: CD-11--AR226-1030a (290 documents).

Page 1 of 3 — 290 documents
Title / Summary Year AR226 Docket Hash ID Pages
This document is an analytical report from Centre Analytical Laboratories detailing the fluorochemical characterization of drinking water, surface water, sediment, and leachate samples from Port St. Lucie, Florida, specifically analyzing for perfluorooctane sulfonate (PFOS), perfluorooctane sulfonamide (PFOSA), and perfluorooctanoate (POAA) using 2003 AR226-1030 xdbRyjaMG2n6Bm71J0wkZN99m 65
This is a cover letter addressed to the USEPA regarding fluorochemical submissions, including sections on toxicology, epidemiology, and environmental studies. 2001 AR226-1030 rgk7RvxaEYrVXe8mK7NxzQnr 1
This document includes attachments related to toxicology, epidemiology, and medical surveillance studies on perfluorinated compounds, specifically detailing a pharmacokinetic study of perfluorooctanesulfonamide (PFOSA) and a solubility study of perfluorooctanesulfonate (PFOS) conducted by 3M. 2001 AR226-1030 day0gRK5KD5wa6kwGXeZOppbQ 1
The document provides an attachment to a letter from 2001 regarding 3M's submission of toxicology, epidemiology, and medical surveillance documents related to N-Methyl Perfluorooctane Sulfonamidoethanol (NMeFOSE), including a report on the presence and concentration of perfluorinated compounds in liver and serum samples. 2001 AR226-1030 n9NM3a2KGy0dXekKL0nKo1n5G 1
This document outlines various toxicology, epidemiology, and medical surveillance studies related to fluorochemicals, specifically focusing on PFOA and PFOS, conducted by 3M, including mortality studies of workers at their Cottage Grove and Decatur facilities, serum fluorochemical levels among employees, and identification of fluorochemicals in human tissue. 2001 AR226-1030 oDXrYnO53QBk1BadmRoJaaOvw 1
The document is an attachment to a letter from 3M to the TSCA 8(e) docket, detailing supplemental findings from studies on N-Ethyl Perfluorooctane Sulfonamidoethanol (N-EtFOSE), including a 104-week dietary carcinogenicity study and reproductive toxicity studies in rats and rabbits, with analytical results concerning the presence of PFOS and 2001 AR226-1030 D01rYzYjrQv0zx9K72gDB7ka 1
This document includes various toxicology and epidemiology studies related to Perfluorooctane Sulfonate (PFOS) conducted by 3M, detailing findings from a 28-day oral toxicity study in rats and preliminary statistical results from a 104-week dietary chronic toxicity study, along with a developmental toxicity study in rabbits. 2001 AR226-1030 2RZe5LdDwbraJJK8ejXoe4KJg 2
The document is a bibliography of published literature related to perfluorinated compounds, specifically focusing on studies involving perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS), compiled by 3M for submission to the EPA. 2001 AR226-1030 g21jDpd1Zapyj1LMbgvrkZNga 2
3M contracted with Pacific Northwest National Laboratory and Focus Environmental, Inc. to analyze the thermal stability of perfluorooctane sulfonate (PFOS), finding that its low carbon-sulfur bond energy suggests it would be effectively destroyed during incineration, indicating that incineration is unlikely to significantly contribute to PFOS generation and distribution. 2001 AR226-1030 KR6LRRxwkqvBb83VGoMRMm9o0 1
This document appears to be a report on fluorochemical decomposition processes authored by David A. Dixon from the Pacific Northwest National Laboratory, but the text is largely unreadable due to OCR errors. 2001 AR226-1030 yyxNQEQQoXbgGbzXL7nqnMK6 6
This document is a letter report from Focus Environmental, Inc. to 3M Corporation discussing the thermal stability of perfluorinated alkyl sulfonyl compounds, highlighting their high thermal stability compared to chlorinated organics and hydrocarbons, and referencing a Battelle report on the thermal decomposition of fluorochemicals. 2001 AR226-1030 V057wnQn4BZ6L44ZeGmjkRD4 8
3M is submitting additional data on perfluorooctane sulfonates and related compounds to the EPA, including new studies and previously unsubmitted reports, as part of their ongoing communication regarding fluorochemicals. 2001 AR226-1030 e73gK17J3RRrKYM27n4rabRO9 4
The document reports on the analysis of alfalfa samples from the 3M Cordova Plant for PFOS, PFOA, and other fluorinated compounds, indicating that due to inadequate sampling procedures and low recovery rates, the analytical results are not recommended for interpretation, and all harvested alfalfa was subsequently landfilled. 2001 AR226-1030 LJ9BQzJ55XadYNXV8Jbnjy0yb 6
This document reports on a monitoring study conducted by Entrix, Inc. for 3M, which analyzed concentrations of selected fluorochemicals, including PFOS and PFOA, in surface water, sediments, clams, and fish near the 3M facility in Decatur, Alabama, revealing significant variations in PFOS levels at different sampling locations. 2001 AR226-1030 rBpRDXX1OKe0N7eQJGZeVXyne 84
The document discusses responses to field audit comments regarding the use of a modified Method TO-13 for air sampling of perfluorinated compounds (FCs) in a multi-city study conducted by 3M Corporation. 2001 AR226-1030 NemaYe7rV68k82BEJJQBVNy8y 4
The document outlines environmental sampling sites for a multi-city study on sulfonated perfluorochemicals, specifically for 3M Specialty Materials, as prepared by Battelle Memorial Institute. 2001 AR226-1030 QM2ykvbyxM3zNmwkxzyVX65Jo 18
The document outlines the Standard Operating Procedure (SOP) for collecting air samples of semi-volatile organic compounds, including perfluorinated compounds, using a high volume polyurethane foam sampling method as part of the Multi-Cities Project conducted by Battelle Memorial Institute. 2001 AR226-1030 jybjqoqERvBY4zLQK2yqpBGMk 42
Pace Analytical Services, Inc. conducted a water resampling and area investigation for the Port St. Lucie Multi-City Study, contracted by 3M, to confirm previous findings related to perfluorinated compounds from earlier sampling events in 1999 and 2000. 2001 AR226-1030 6b2zGw7k6de8O2qEDoNL7QxOg 49
The document summarizes the findings of a Multi-City study conducted by 3M Environmental Laboratory to analyze the presence of perfluorinated compounds, specifically PFOS, PFOA, and FOSA, in various environmental samples from cities with and without fluorochemical manufacturing, including locations like Decatur, Alabama, and Cleveland, Tennessee. 2001 AR226-1030 nk0JBXqbXR8qEg9p0V0OzRBa1 12
The document summarizes the results of a Multi-City study conducted by 3M Environmental Laboratory to analyze the presence of perfluorinated compounds, specifically PFOS, PFOA, and FOSA, in various environmental samples from cities with and without fluorochemical manufacturing. 2001 AR226-1030 pBGExMv7w0oeRGLXOB4rkk48D 12
The document reports on the solubility testing of N-ethylperfluorooctane sulfonamidoethanol (N-EtFOSE OH), finding it to have low solubility in pure water (151 mg/L) but high solubility in methanol and acetone (greater than 10% w/v). 2001 AR226-1030 nmq3Xx2B32rkRoyvJqX2KVqN1 2
The document is a laboratory report from 3M Environmental Laboratory detailing the hydrolysis reactions of perfluorooctanoic acid (PFOA), indicating non-compliance with certain EPA Good Laboratory Practices while adhering to many quality assurance procedures. 2001 AR226-1030 Ra3Z1LY98JQNKQNmzX279vK0z 99
The document is a laboratory report from 3M detailing the hydrolysis reactions of 2-(N-ethylperfluoroctanesulfonamido)-Ethyl Alcohol (N-EtFOSE Alcohol), noting non-compliance with EPA Good Laboratory Practices while indicating that the study's analytical methods were based on GLP standards. 2001 AR226-1030 2JygEj3R8rXGa08Rbab5Jqpw5 85
The document is a laboratory report (No. EL1132) from 3M Environmental Laboratory detailing a study on the hydrolysis reactions of Perfluorooctanesulfonamide (FOSA), which notes non-compliance with certain EPA Good Laboratory Practices standards. 2001 AR226-1030 ByM1V7ewgNrYQLN880yKy4J3w 126
The document is a laboratory report from 3M Environmental Laboratory detailing a study on the hydrolysis reactions of Perfluorooctane Sulfonate (PFOS), which was found to be non-compliant with US EPA Good Laboratory Practices Standards. 2001 AR226-1030 xjkLEeOJ6Ja644DX6GVro7bDm 72
The document reports on a hydrolysis stability study of N-ethylperfluorooctane sulfonamidoethanol (W-EtFOSE alcohol) conducted by 3M, finding no formation of PFOS and estimating a minimum pseudo first order hydrolytic half-life for W-EtFOSE alcohol. 2001 AR226-1030 wq1ZM0MKwQB5bdVpqYK4Ddg6E 3
The document is a laboratory report from 3M detailing the hydrolysis reactions of 2-(N-Methylperfluoroctanesulfonamido)-Ethyl Alcohol (N-MeFOSE Alcohol), indicating non-compliance with certain EPA Good Laboratory Practices while noting revisions made to better represent the experimental results. 2001 AR226-1030 mBd4pMb719Mvo4K8R6BZ0dvoO 72
The document reports on a hydrolysis stability study of perfluorooctanesulfonamide (FOSA), indicating that no PFOS formation was detected and that FOSA showed no degradation across various pH levels, with a minimum pseudo first-order hydrolytic half-life estimated under specific assumptions. 2001 AR226-1030 zbbOeOOkXpKeyZK5MVj17K6pm 2
The document reports on a hydrolysis stability study of N-methylperfluorooctane sulfonamidoethanol (W-MeFOSE alcohol), produced by 3M, which found no formation of PFOS and estimated a minimum pseudo first-order hydrolytic half-life for W-MeFOSE alcohol across various pH levels. 2001 AR226-1030 8zd4jdYa496382yNNq93O9aB 3
The document reports on a hydrolysis stability study of perfluorooctanoic acid (PFOA) ammonium salt conducted by 3M, indicating that the hydrolytic half-life of PFOA at 25°C is estimated to be greater than 92 years based on analytical results from various pH levels. 2001 AR226-1030 ZndjJG3zBg1rmK0pydBdQnVQ7 2
The document reports a study conducted by 3M Company on the stability of perfluorooctanesulfonate (PFOS) in water, finding that its hydrolytic half-life is greater than 41 years and that degradation does not depend on pH. 2001 AR226-1030 JraZwgr5eLXO3MwddeB93a8x2 2
The document reports that perfluorooctanoic acid, ammonium salt (PFOA), produced by 3M, was found to be highly soluble in pure water, methanol, and acetone, with solubility concentrations exceeding 10% (w/v) for each solvent. 2001 AR226-1030 Z4ogXzZjjwB2bRKLdqw8p4Lw8 2
The document discusses the thermal stability and degradation pathways of perfluorooctane sulfonate (PFOS) through combustion processes, indicating that PFOS has low thermal stability due to weak carbon-sulfur bonds, and suggests that incineration is unlikely to significantly contribute to PFOS generation and distribution. 2001 AR226-1030 85y2O3V310nGXqndvoDxEmrXd 1
This is a document titled "Fluorochemical Decomposition Processes" authored by David A. Dixon from the Pacific Northwest National Laboratory, discussing theoretical modeling and simulation related to fluorochemical decomposition. 2001 AR226-1030 xjMDjQxEdRLN11bELoJxr00n6 6
This letter report from Focus Environmental, Inc. to 3M Corporation discusses the thermal stability of perfluorinated alkyl sulfonyl compounds, highlighting their high thermal stability compared to chlorinated organics and hydrocarbons, and referencing a Battelle report on the thermal decomposition of fluorochemicals. 2001 AR226-1030 k9pBb8yjzvXgeJK9R5y12Qjvy 8
This document details an acute contact toxicity study of perfluorooctanesulfonate (PFOS) conducted on honey bees (Apis mellifera) using a test substance produced by 3M, with a purity of 86.9%, to assess its effects under controlled laboratory conditions. 2001 AR226-1030 G6kZOZKNmNE2LmO28LDNO92En 32
3M submitted a TSCA 8(e) notice to the EPA detailing acute toxicity studies on perfluorooctane sulfonate (PFOS) conducted on honey bees, revealing a contact LD50 of 59.7 mg/Kg (moderately toxic) and an oral LD50 of 5 mg/Kg (highly toxic). 2001 AR226-1030 rKEgXjMRX2wQgz7KjkYoeBoG 1
The document details an acute oral toxicity study of perfluorooctanesulfonate (PFOS) conducted on honey bees (Apis mellifera) using a test substance produced by 3M, with a purity of 86.9%, following OECD Guideline 213. 2001 AR226-1030 remvGr5qnXVnBjzrzG2X76deG 43
This laboratory report from 3M Environmental Technology & Safety Services details a PFOS dietary LC50 study in northern bobwhite, revealing that while PFOS levels in liver tissues were consistent across dosage groups, sera levels exhibited significant variability, complicating data interpretation. 2001 AR226-1030 xYQ0RYqOOyXvpYXnmgXd5RqE 16
The document is an analytical report from the 3M Environmental Laboratory detailing the presence and concentration of PFOS, M556, PFOSAA, and PFOSA in the liver and sera of rats exposed to EtFOSE-OH, conducted under Good Laboratory Practice regulations. 2001 AR226-1030 NEXZLKxzYQ3z3D6bvkO8znN7w 143
The document reports on a screening conducted by 3M Environmental Laboratory to assess PFOS levels in various feed matrices for wildlife, finding PFOS below quantitation limits in avian feed and not detected in yeast-cerophyll-trout chow or green algae, while detecting PFOS at 9-10 ug/kg in dry artemia cysts, which is not expected to impact toxicity studies using the 2001 AR226-1030 75DkJJo9dwz6dxVgN7j2v9y6 1
The document details a bioconcentration test of perfluorooctanesulfonate (PFOS) produced by 3M, indicating a purity of 86.9% and describing the methodology, conditions, and results of the study conducted on bluegill fish to assess PFOS uptake and depuration. 2001 AR226-1030 0gm8R4EBB90r0eLbozbK7grwM 5
The document details an acute contact toxicity study of perfluorooctanesulfonate (PFOS) conducted on honey bees (Apis mellifera) using a test substance produced by 3M, with a purity of 86.9%, under controlled laboratory conditions. 2001 AR226-1030 D2egLMDDk4yjQg2D0RweovzM 4
The document details a toxicity test of perfluorooctanesulfonate (PFOS) on the freshwater diatom Navicula pelliculosa, using a sample from 3M with a purity of 86.9%, conducted under GLP conditions over a 96-hour exposure period. 2001 AR226-1030 3JdDkGzjoEJo77MewLJVrejby 6
The document details a toxicity test of perfluorooctanesulfonate (PFOS) on the marine diatom Skeletonema costatum, conducted by Wildlife International Ltd. in 2001, with a purity of 86.9% and various analytical monitoring methods employed over a 96-hour exposure period. 2001 AR226-1030 aD4p4REDm4pqvQQaxQ7B8m01e 5
The document details a toxicity test of perfluorooctanesulfonate (PFOS) on the aquatic plant Lemna gibba G3, using a sample from 3M with a purity of 86.9%, conducted under GLP conditions in 2001. 2001 AR226-1030 EmaBa3kz9go5eg2N0y0O9wpe0 6
This document details a toxicity test of perfluorooctanesulfonate (PFOS) on the freshwater diatom Navicula pelliculosa, conducted under GLP conditions with a purity of 86.9%, to assess its impact on aquatic plant growth over a 96-hour exposure period. 2001 AR226-1030 NG2jRj2kEQ1O4jVLM5z4yRxpw 6
The document details a toxicity test of perfluorooctanesulfonate (PFOS) on the freshwater alga Anabaena flos-aquae, using a sample from 3M with a purity of 86.9%, conducted under GLP conditions in 2001. 2001 AR226-1030 X73qdbmgbrgq6w9mzL7rge0gy 6
The document details an acute contact toxicity study of perfluorooctanesulfonate (PFOS) on honey bees (Apis mellifera), conducted under GLP conditions, with a purity of 86.9%, using a test substance prepared in acetone. 2001 AR226-1030 k9mp3mRnYBwDZ0qqykb8kOgpy 4
This document details a FETAX (Frog Embryo Teratogenesis Assay) study conducted on perfluorooctanesulfonate (PFOS) obtained from a 3M production lot, with a purity of 86.9%, to assess its effects on Xenopus laevis embryos over a 96-hour exposure period. 2001 AR226-1030 GmDVXdMp9M5G2Lpw7VbpYa45x 6
The document details an acute oral toxicity study of perfluorooctanesulfonate (PFOS) on honey bees (Apis mellifera), conducted according to OECD Guideline 213, with a test substance purity of 86.9% and specific test conditions outlined. 2001 AR226-1030 jygNv7yDD40dXOkGqypjVxG95 4
This document details a toxicity test of perfluorooctanesulfonate (PFOS) on the aquatic plant Duckweed (Lemna gibba G3), conducted by Wildlife International Ltd. under GLP conditions, with a focus on the effects of PFOS at various concentrations over a 7-day exposure period. 2001 AR226-1030 4ERpgVMDxX8gXdvNBER6Z4xp 6
The document reports that the water solubility of perfluorooctanesulfonate (PFOS) was determined to be 680 mg/L in pure water using a shake flask method, with the study conducted by 3M Company in 2001. 2001 AR226-1030 gDnd61MR1ORw88krnEBBVEYGq 2
The document reports the solubility of perfluorooctanesulfonate (PFOS) in octanol, finding an overall mean solubility concentration of 56.0 mg/L based on tests conducted by 3M Company. 2001 AR226-1030 K69ZLe8LO5vwRyRmBdwaj5re6 2
The document reports on the water solubility of perfluorooctanesulfonate (PFOS) in natural seawater and a 3.5% sodium chloride solution, finding it to be slightly soluble with concentrations of 12.4 mg/L and 20.0 mg/L, respectively. 2001 AR226-1030 RJnVNy38JRgbNXyE4B5KwJ6Ma 2
This document details a soil adsorption study of Perfluorooctanesulfonate (PFOS), including its purity, testing methods based on OECD guidelines, and the characteristics of various soil types used in the experiment. 2001 AR226-1030 rxRD07Gva5XoEjrGX1q6VMa1a 4
This document reports on a bioconcentration test for perfluorooctanesulfonate (PFOS) conducted by 3M Company, revealing a calculated n-octanol/water partition coefficient (logKow) of -1.08 at saturation, indicating that no environmental conclusions can be drawn from the results. 2001 AR226-1030 jBMzkRm3zQ7jEV110Jy7GyQk 2
The document is an archived final report from an environmental laboratory detailing the results of toxicity tests on a product identified as L-6778, which contains perfluorinated compounds, with findings indicating high levels of toxicity in various tests. 2001 AR226-1030 B8Lw8EaZNa1pNd2oOb8jdGymo 10
The document is an archived final report from an environmental laboratory detailing the results of a toxicity assessment on a sample identified as L-6778, which includes various biochemical oxygen demand (BOD) and chemical oxygen demand (COD) measurements, indicating high levels of toxicity. 2001 AR226-1030 LoJzQqEzoQ9eMqrXZb6ZK3wRX 9
The document is a 3M Environmental Laboratory report on the indirect photolysis of gaseous perfluorooctanesulfonyl fluoride (POSF) using Fourier Transform Infrared (FTIR) Spectroscopy, which states that the study does not comply with US EPA Good Laboratory Practices standards. 2001 AR226-1030 6gdnovY23zp03DOaREebZnNm 38
The document reports a screening study conducted by 3M Company in 2001 that determined the water solubility of perfluorooctanesulfonyl fluoride (POSF) to be less than 0.294 mg/L at 22-24°C, with visible droplets remaining after equilibration. 2001 AR226-1030 R20XwJBeD3VM27Yrzkw3j2eMa 2
The document is a 3M Environmental Laboratory report on the indirect photolysis of gaseous perfluorooctanesulfonyl fluoride (POSF) using Fourier Transform Infrared (FTIR) spectroscopy, which states that the study does not comply with US EPA Good Laboratory Practices standards. 2001 AR226-1030 2qjde7kk3qoz9Yd2ryrZqyea7 38
The document is an analytical report from 3M Environmental Laboratory detailing the determination of the presence and concentration of PFOS, PFOSA, M556, and M570 in liver and serum samples from a 13-week dietary study on rats, conducted under FDA Good Laboratory Practice regulations with noted exceptions. 2001 AR226-1030 Ra2dEGooyMJYq46j4GgZw5k8 130
The document is a report on a 35-day aerobic biodegradation study of PFOS conducted by Pace Analytical Services for 3M, detailing the project's initiation and completion dates along with the study director's information. 2001 AR226-1030 gNErBOyegZbvKqaN6N3ZRa3e 30
This document details a biodegradation study of N-Ethylperfluorooctanesulfonamide (N-EtFOSA), produced by 3M, conducted under aerobic conditions using activated sludge from a wastewater treatment plant, with results calculated assuming 100% purity of the test substance. 2001 AR226-1030 O351JjOjGmbvdyypD3OBgE7bp 4
This document details a biodegradation study of perfluorooctanesulfonamide (FOSA), conducted in 2001 using activated sludge from a wastewater treatment plant, following EPA guidelines, to assess its degradation under aerobic conditions. 2001 AR226-1030 ZBV4YwKjm0LGbV5VGrX8oqRo8 3
This document details a biodegradation study of Perfluorooctanesulfonylamido(ethyl)acetate (N-EtFOSAA, CAS # 2991-51-7) conducted using activated sludge from a wastewater treatment plant, following EPA guidelines, with a focus on its aerobic degradation over 18 days. 2001 AR226-1030 OJ7K8GV03XGD6y1gVrveanzbX 3
This document details a biodegradation study of perfluorooctanoic acid (PFOA), produced by 3M, using activated sludge from a wastewater treatment plant, with results indicating a test concentration of 2.645 mg/L over an 18-day incubation period. 2001 AR226-1030 pp1dO3pz5pKjpZNNpe1dk5vgX 3
This document outlines a biodegradation study of perfluorooctanesulfonate (PFOS) conducted using activated sludge from a wastewater treatment plant, reporting a test concentration of 2.582 mg/L and detailing the methodology based on EPA guidelines. 2001 AR226-1030 KzxQJp2X6jMGVXNRqZ9pnaa7r 4
The document is a final report on a mortality study conducted by the University of Minnesota, which found no significant association between occupational exposure to perfluorooctanoic acid (PFOA) at the 3M Cottage Grove facility and overall cancer mortality, although a modest increased risk of death from cerebrovascular disease was observed in workers with definite PFOA exposure. 2001 AR226-1030 e7DYb8rvRgq7EaKem5bVxmKLq 28
The document discusses a study by 3M Company analyzing health outcomes of employees at the Decatur Chemical and Film Plant from 1993 to 1998, emphasizing the use of administrative databases for morbidity research related to potential health impacts from exposure to perfluorinated compounds. 2001 AR226-1030 Dd3Veqrm2rLza9aJ9G6Yyy1rN 134
The document is a final report on a mortality study conducted by Bruce H. Alexander, PhD, which investigates the relationship between occupational exposure to perfluorooctanesulfonyl fluoride (POSF) based fluorochemicals and mortality among employees at the 3M facility in Decatur, Alabama, finding lower overall mortality rates than expected but elevated risks for bladder cancer among high-exposed workers 2001 AR226-1030 5DxRygmvb7QJV3Nn9EpZxjjbV 32
The document is a final report from 3M Company detailing a study on serum levels of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHS) among 45 employees engaged in fluorochemical research, revealing geometric mean serum levels of 0.116 ppm for PFOS 2001 AR226-1030 MJMXpgLqneOpzr1OMM6L8jNjx 6
The document reports on a study conducted by 3M Company measuring serum levels of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) among 258 employees at the Antwerp chemical plant, finding geometric mean levels of 0.44 ppm for PFOS and 0.33 ppm for PFOA, with higher exposure levels 2001 AR226-1030 X81Nv74epabwLMDpe5oY1dzpd 39
The report from 3M Company details a medical surveillance program conducted in 2000, revealing that serum levels of perfluorooctanoate (PFOA) among Decatur chemical plant employees increased to a geometric mean of 1.13 ppm, particularly among cell operators, while perfluorooctanesulfonate (PFOS) levels remained stable compared to 1998 2001 AR226-1030 oyorJmRzK6ak7MXD41ZQYZ0w 36
The document is a final report from 3M Company detailing a study on the identification of perfluorooctanesulfonate (PFOS) in human tissue, which found that average serum levels in non-occupationally exposed humans were significantly lower than those observed in cynomolgus monkeys during a feeding study. 2001 AR226-1030 DdXvnJqQbQyrRBB1mzox2JDgB 35
This interim report from 3M Company details a study on the distribution of perfluorooctanesulfonate (PFOS) in serum samples from over 600 adult blood donors in the United States, aiming to characterize the presence of fluorochemicals in the general population. 2001 AR226-1030 rpKRnD04B1nkxdveLv41Zqe9e 5
This interim report from 3M Company details a study on the identification of perfluorooctanesulfonate (PFOS) and other fluorochemicals in serum samples from 599 children aged 2 to 12 in the United States, aiming to characterize the distribution of these substances in the population. 2001 AR226-1030 EvYy6gOnLJJqqw4LvQ98o5EBb 5
3M submitted a supplemental toxicokinetic study of perfluorooctane sulfonamide (PFOSA) to the EPA as part of their ongoing dialogue regarding fluorochemistry and to fulfill a previous omission from their data submissions. 2001 AR226-1030 61pMLpvzBQn3DNjY0QvYdgGm 22
3M reported on April 25, 2001, that their ongoing study of the serum half-life of perfluorooctane sulfonate (PFOS) in retired workers revealed a mean half-life of 303 days based on data from 18 of 27 employees, which is an improvement over previous estimates but cautioned that the data are difficult to interpret. 2001 AR226-1030 LpeJp9n1omajEwNv3QM0KZr35 2
The document is a summary of analytical results for perfluorinated compounds, including PFOA and PFOS, from samples drawn in 1995, indicating various concentrations detected in blood samples. 2001 AR226-1030 4Qb5bBMdBZna9vb4ZY5OKw3Lx 2
3M submitted acute toxicity test results for perfluorooctane sulfonate (PFOS) on honey bees, indicating a contact LD50 of 59.7 mg/Kg (moderately toxic) and an oral LD50 of 5 mg/Kg (highly toxic), while asserting that environmental exposure levels are unlikely to reach these toxicity levels. 2001 AR226-1030 gaGXBkbzg0eb5qLEYpmbYQ5DN 2
3M submitted a TSCA 8(e) substantial risk notice to the EPA regarding a two-year dietary study of potassium perfluorooctanesulfonate (PFOS) in rats, indicating that preliminary statistical findings suggest potential risks that will be further evaluated in the final report. 2001 AR226-1030 G6OvYop2O9vE1v1GLooxMzzym 2
3M is supplementing its previous notice to the EPA regarding a two-year dietary study of N-ethyl perfluorooctanesulfonamidoethanol (N-EtFOSE) in rats, highlighting statistically significant increases in thyroid follicular-cell tumors in male rats, with a final report forthcoming. 2001 AR226-1030 XO1Nq61ZkgjOdg2yEO8JNRxX4 2
3M submitted a supplemental report to the EPA detailing preliminary findings from a study on perfluorooctane sulfonate (PFOS) that investigates its potential toxicity and effects on perinatal mortality in rats, including a focus on cholesterol synthesis and serum lipid levels. 2001 AR226-1030 Q2Gy8vEx64yVEK1Jdxd2g96R 5
The document summarizes multiple studies conducted by the University of Minnesota on the serum levels of fluorochemicals, including PFOA and PFOS, among workers at 3M facilities and in children's sera, highlighting findings from medical surveillance and epidemiological analyses. 2000 AR226-1030 MyQp4mdb7RgqbRDD776MqwBL 2
The document outlines the design and methodology of a Multi-City study submitted to 3M Environmental Laboratory, aimed at assessing the dispersion of fluorochemical compounds, including those produced by 3M, in the environment and their potential impact on human exposure through water and food sources. 2000 AR226-1030 2qd3nRX3VeZMb0EZOz4KQ4D66 7
Pace Analytical Services, Inc. conducted resampling for the Port St. Lucie Multi-City Study under contract with 3M to confirm baseline information on fluorochemicals, specifically targeting PFOS, PFOSA, POAA, PFHS, and TFA, originally sampled in July 1999. 2000 AR226-1030 2rk5v0qOQrM40583KwYvZ53r 13
The document details a study conducted by Pace Analytical Services, Inc. under contract with 3M to collect food samples from three study cities and three control cities to estimate the dietary intake of fluorochemicals, including PFOA and PFOS, by local residents. 2000 AR226-1030 B5azb4Z2od2odv6qJey6QKvVE 60
This report details the accumulation of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in the livers of mink and river otters, finding PFOS present in all mink samples with a maximum 2000 AR226-1030 K61bw0XGnMnXK9o9JnERbj3XX 14
This report details a monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanoic acid (PFOA), and related fluorochemicals in fish tissues, finding the highest PFOS concentration at 923 ng/g in fish from Belgium, while PFOA and other fluorochemicals were rarely detected. 2000 AR226-1030 mp2Zq3GadLG4gdBYkjkwv2oOB 38
This document reports on a study measuring concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in oysters from the Gulf of Mexico and Chesapeake Bay, finding PFOS in 51 of 2000 AR226-1030 emk4Or2gQQvwdNqxNE8V2VrYy 19
This report details a global monitoring survey of perfluorooctane sulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoic acid (PFOA), and perfluorohexanesulfonate (PFHS) in marine mammals, revealing that PFOS was commonly detected in liver and blood samples from various locations, 2000 AR226-1030 QKkXxYL262Kq9YRyQgDnZ61k 56
This report details a global monitoring survey of perfluorooctanesulfonate (PFOS), perfluorooctanesulfonamide (FOSA), perfluorooctanoate (PFOA), and perfluorohexanesulfonate (PFHS) in fish-eating water birds, revealing significant concentrations of PFOS in various bird tissues, particularly noting high 2000 AR226-1030 kmaXkX88GazVQZpm9a1LkG13n 60
The document describes an experiment using thermospray mass spectrometry to investigate the volatility of FC-95 and FC-143, specifically testing their vapor pressure and removal from solutions when air is bubbled through them. 2000 AR226-1030 mBv7yM9DGGO66r1R3ggKOY0g 20
The document is an archived final report detailing laboratory analyses of surfactants, specifically FC-95 and Sultone Foamer, with results indicating high concentrations of these substances, prompting a request for retesting due to initially unexpected high values. 2000 AR226-1030 L5pn5RBb1evLxMQ0Qq24na03 9
This document is a study report on the microbial metabolism (biodegradation) of perfluorooctane sulfonate (PFOS), conducted by Springborn Laboratories and submitted to 3M Environmental Laboratory. 2000 AR226-1030 XOK51B8oanYYRkKQBymonde9J 36
The document reports on a study conducted by Springborn Laboratories, Inc. on the aerobic soil biodegradation of perfluorooctane sulfonate (PFOS), completed on October 31, 2000, for 3M Environmental Laboratory. 2000 AR226-1030 RJrZ2XkDKYMB0QRyx0GJK1bg8 17
This document reports on a study conducted by Springborn Laboratories, Inc. on the anaerobic biodegradation of Perfluorooctane Sulfonate (PFOS), submitted to 3M Environmental Laboratory, with completion dated October 31, 2000. 2000 AR226-1030 8ObgRD3pyGL6jJ8JqR2D3Mbe 16
The document is a study report on the microbial metabolism (biodegradation) of Perfluorooctane Sulfonate (PFOS), completed by Springborn Laboratories for 3M Environmental Laboratory, detailing the methodology and findings related to PFOS degradation. 2000 AR226-1030 x1G0JjQJ8xNwE4qV6E0DJ8Y21 21